Psych Drugs

Front 1

Least anticholinergic TCA's

Back 1

Desipramine
Nortriptyline

Front 2

TCA with least orthostatic hypotension

Back 2

Nortriptyline

Front 3

Tertiary amine preferentially work on which amine

Back 3

Serotonin (esp clomipramine)

Front 4

Secondary amine act more on?

Back 4

NE (es desipramine)

Front 5

Mechanism of Action for Venlafaxine

Back 5

SSNRI

Front 6

Advantage of Venlafaxine

Back 6

10% greater rate of full reminission

Front 7

Duloxetine

Back 7

Like venalafaxine but more balanced effect on seritonin and norepi

Can be given at full dose initially

Front 8

Uses for Buproprion

Back 8

Bipolar Depression
ADHD
Smoking Cessation

Slightly higher seizure risk than TCA's

Front 9

Use for Buspirone

Back 9

Generalized anxiety disorder

Front 10

DOC for generalized anxiety disorder

Back 10

Buspirone

Front 11

Trazadone

Back 11

Sedative
Useful in agitated dementia

No real side effect issues

Front 12

Nefazodone

Back 12

Like traz but with less sedation and REM sleep supression

May cause liver failure so being removed from the market

Front 13

Anti-Depressant with less sedative effects than other.

May have serious side effect

Back 13

Nefazodone

Liver failure

Front 14

Carbamazepine

Back 14

Mood stabilizer and broad spectrum anti-convulsant. Also works for neuralgia.

Better than Li for mixed states

Front 15

Better than Li for Bipolar with mixed episodes or rapid cycling

Back 15

Carbamazepine

Front 16

Note as good of a anti-depressant as Li but as good for manic states

Back 16

Valproate

Rare side effect of fatal hepatotoxicity, hemorrhagic pancreatitis and agranulocytosis in those under two years of age with other anticonvulsants

Front 17

Don't give this drug to kids under 2 years old, especially if they are on other anticonvulsants

Back 17

Valproate

Front 18

First approved mantenance tx for bipolar disorder since lithium

Back 18

Lamotrigine

may cause rash, Steve-Johnson syndrome

Go low and slow

Front 19

Indication for ECT

Back 19

Refractory to TX
Need for rapid correction
Catatonia
Refractory Schizophrenia
Pregnant

Front 20

Benzodiazapine antagonist

Back 20

Flumazenil

Front 21

Flumazenil

Back 21

Benzo anatagonist

Front 22

Zolpidem

Back 22

BZ1 selective

Sedation with little disruption of REM sleep

Good for initial insomnia

Front 23

Good for initial insomnia

Back 23

Triazolam
Zolpidem

Front 24

Benzo's given IV

Back 24

Lorazepam and Midazolam

Lorazepam more reliable for acute anxiety, aggitation

Midazolam has shorter half-life, better for anesthesia

Front 25

For actuately agitated patients

Back 25

Lorazepam IV

can be given with haldol

Front 26

Rapid Onset Benzo's

Back 26

Flurazepam, Tempazepam, Quazepam and Triazolam

Front 27

Good for middle insomnia

Back 27

Flurazepam

Long half life, some residual sedation

Front 28

Best for inital insomnia

Back 28

Triazolam

not associated with amnesia dn behavioral changes

Front 29

Bezo'w without active metabolites (for elderly or liver compromised)

Back 29

Lorazepam
Oxazepam
Tempazepam

Front 30

Best benzo's for routine use

Back 30

Lorazepam
Chlordiazepoxide
Clonazepam

Front 31

TX for generalized anxiety disorder

Back 31

Buspirone (low and slow)

Benzo's TCA's and venalafaxine esp. if previously treated with benzo's

Front 32

Tx for Panic Disorder

Back 32

Bezon's acutely, but not monotherapy

Use SSRI or TCA for prophylaxis

Front 33

Tx for Phobic Disorder

Back 33

Behavioral Therapy

Benzo for acute
Benzo for public speaking
SSRI's and MAOI's for Generalized Social Phobia

Front 34

Tx for PTSD

Back 34

TCA's and MAOI's 1st Line
Clondine, Naltrxone or Propranolol
Lithium and Carbamazepine

No Benzo's
SSRI's are good, but may induce arousal and anxiety

Front 35

Tx for OCD

Back 35

SSRI's

Front 36

Best Benzo for Detox

Back 36

Clonazepam

Front 37

Greatest risk for addiction

Back 37

Alprazolam (Xanax)

Short half-life, rapid onset

Front 38

Risk for amnesia

Back 38

Triazolam

Front 39

Secondary Amines preferentially act on what receptors

Back 39

NE more than 5_HT

Desipramine, Nortriptyline

Front 40

Clomipramine preferentially acts on which receptor

Back 40

Serotonin

Front 41

Venlafaxine preferential action

Back 41

SSRI at low dose
More NE action at high dose

Front 42

Duloxetine preferntial action

Back 42

5HT, NE equally

Front 43

Buspirone MOA

Back 43

Pre and Post synaptic Serotonin partial agonist/antagonist

For GAD

Front 44

Trazodone Preference

Back 44

Serotonin anatgonist only