Legionella

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  • Innate Immune System

    Innate immunity constitutes the first line of defense and is fundamental for the recognition and the initiation of an inflammatory response against microorganism. Maintenance of homeostasis is a primary function of the innate immune system and it is achieved through immune surveillance by pattern recognition receptors (PRRs), such as Toll-like receptors (TLRs) and nucleotide-binding domain leucine-rich repeat containing receptors (NLRs). The PRR’s are predominantly expressed by cells of the…

    Words: 1627 - Pages: 7
  • Francisella Tularensis

    Francisella tularensis is an important microbial agent which causes the severe infection of tularemia. The intracellular life cycle of this bacterium is supported by a vast range of protective guards such as enzymes. Although several enzymes are recognized in different subspecies of the bacterium, acid phosphatase and superoxide dismutase are seen in all bacterial subspecies. On the other hand, the most important enzymatic system relating to host cells is NADPH oxidase. For this reason, the…

    Words: 1621 - Pages: 7
  • Francisella Tularensis Essay

    Background: Francisella tularensis (F.tularensis) is the etiological microorganism for tularemia. There are different forms of tularemia such as respiratory tularemia. Respiratory tularemia is the most severe form of tularemia with a high rate of mortality; if not treated. Therefore, traditional microbiological tools and Polymerase Chain Reaction (PCR) are not useful for a rapid, reliable, accurate, sensitive and specific diagnosis. But, DNA microarray technology does. DNA microarray technology…

    Words: 1778 - Pages: 8
  • Sick Building Syndrome Case Study

    CHAPTER ONE INTRODUCTION 1.1 RESEARCH BACKGROUND The US Environmental Protection Agency (EPA) and the US Consumer Product (1995) (as cited in Preethi, 2005) sated that people spend approximately 90 percents of their time being indoors. Therefore, for many, due to more exposure of indoor air pollution than outdoor air pollution the risk to health may be greater. The building occupants may be exposed to the variety of contaminants whether in the form of gases and particles derived from office…

    Words: 3302 - Pages: 14
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