Phagocytosis

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    Endochondral Ossification All osteogenic tissue from the neck down is made by endochondral ossification, with the exception of the clavicles. The model that bone will eventually replace is composed of hyaline cartilage, the most common cartilage, this process tends to be more difficult than intramembranous ossification since all hyaline cartilage most be decomposed as bone tissue is created. Everything begins at the primary ossification center, which is located in the center of diaphysis of the…

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    Pathogenesis Essay

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    enable the bacterium to attack have cells can be encoded on plasmids, however more frequently are on the chromosome (Peterson, 1996). Capsules: Numerous microscopic organisms are encompassed by containers that shield them from opsonization and phagocytosis (Peterson, 1996). Endotoxins: The lipopolysaccharide endotoxins on Gram-negative microbes cause fever, changes in circulatory strain, irritation, deadly stun, and numerous other harmful occasions (Peterson, 1996). Exotoxins: Exotoxins…

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    pneumococci that makes the lungs tissue the red appearance. Then from red it precedes to gray hepatizaion which makes the affected tissue becomes gray due to decrease blood flow, deposition of fibrins over the pleural surfaces, the presence of phagocytosis takes place so fast in the alveoli (Lewis et al., 2014 p. 663). Then resolution phase takes place where in the alveolar space there are increased number of macrophages that could be seen then it removes degenerative neutrophils ( immature…

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    Francisella Tularensis

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    Francisella tularensis is an important microbial agent which causes the severe infection of tularemia. The intracellular life cycle of this bacterium is supported by a vast range of protective guards such as enzymes. Although several enzymes are recognized in different subspecies of the bacterium, acid phosphatase and superoxide dismutase are seen in all bacterial subspecies. On the other hand, the most important enzymatic system relating to host cells is NADPH oxidase. For this reason, the…

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    type III secretion system (T3SS) comprised of a needle-like apparatus used to inject exoenzymes into neighboring cells (1, 3). These toxic effector proteins enable P. aeruginosa to spread throughout the host while evading immune responses such as phagocytosis (REF). The T3SS is regulated through several pathways, one of which is the RsmAYZ system (3). This pathway is composed of…

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    pathogen and binding to the antigen epitopes so the pathogen is essentially useless. Agglutination typically will occur, especially with bacteria, creating a clump of antibodies and pathogens. This makes it much easier for macrophages to find for phagocytosis. Then using compliment proteins, the antibodies…

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    Rituximab Case Study

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    B-cells from usual to unusual levels. There are three chief mechanisms through rituximab acts in the body. One process by which the B-cell is demolished by direct ingestion of the B-cell by the effector cell in a development called antibody-dependent phagocytosis but this play very little part in B-cell demolition. A second and very significant process studied that antibody-dependent cellular cytotoxicity (ADCC) where undamaged B-cell is not swallowed or phagocytized but definite effector…

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    The Human Immune System

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    Links between the human immune system, pathogens, antibiotic resistance and mutations are discussed in this report. It is stated that the antibiotic resistance and overuse of vaccine has contributed to the increased incidence of emerging diseases and resistance to their controls and treatments. The human immune system is the protection of the body against potentially damaging foreign bodies and other disease. Pathogens are organisms, including a bacterium, a virus or a fungus and these causes…

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    proteins. Large molecules like polysaccharides and proteins, cross the membrane with the help of vesicles. Endocytosis is when the cell takes in macromolecules by forming vesicles from the plasma membrane. There are three types of endocytosis: phagocytosis (cellular eating), pinocytosis (cellular drinking), and receptor-mediated. Endocytosis has to do with large substances coming into the cell. Exocytosis is when transport vesicles migrate to the membrane and then fuse with it and release their…

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    Systemic Immune System

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    The interaction between the CNS and the systemic immune system is delicate, being limited by the presence of the blood brain barrier (BBB), which renders the CNS immune homeostasis in a dormant self-tolerant state (1). Selective permeability of the BBB plays a crucial role in regulating the entry of specific molecules into the CNS and excluding most macromolecules from passing into the brain (2, 3). This unique feature of the BBB also prevents leakage of neurotransmitters into the circulation.…

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