Genomics

Prader-Willi syndrome is a genomic imprinting disorder caused by the failure to express SNRPN (small nuclear ribonucleoprotein-associated polypeptide N) gene product. SNRPN is expressed only on the paternal chromosome 15q11-q13, however, the exact genes responsible for Prader-Willi syndrome haven't been identified. People normally inherit one copy of chromosome 15 from each parent. Some genes are active only on the copy that is inherited from a person's father, the paternal copy. Genomic…

Cell Biology and Molecular Biology through in-depth Biomedical studies. However, it is during my current study on the genetic disorder Neurofibromatosis type 1 (NF1) when my passion for the Laboratory Genetics and Genomics was lighted. My passion for the Laboratory Genetics and Genomics was lighted while I am conducting current studies on the genetic disorder Neurofibromatosis type 1 (NF1). However, it has long been deeply rooted since I was keenly aware of the importance of Genetics in health…

eumusae. The initial DNA concentration used was 10,000 ρg/µl. The results showed that the LAMP method detected the genomic DNA of M. eumusae at a very low concentration of 1 ρg/µl of DNA (Fig. 4a). The conventional PCR performed using the outer primers F3 and B3 detected the genomic DNA of M. eumusae only up to 1000 ρg/µl concentration by producing an amplicon size of 200 bp in agarose gel electrophoresis (Fig.4b). Thus, it can be inferred that the…

component (Badzec, Turner, & Jenkins, 2008). As a nurse, I have the responsibility to participate in education for myself as well as educating the public on the management of disease risks based on genomic information. The Code of Ethics for nurses addresses ethical concepts that apply to genomics and by staying educated on these and following the duties and obligations I have to my patients, I will be providing quality patient care while acting as a nurse…

and biology, is the Bioinformatics. The way it is doing it is by improvement and be able to sequencing DNA (genome). Bioinformatics can be describes as a science tool in which use computer technology to analyze, collect, “storage, and retrieval of genomic data” (American Heritage Dictionary). There are different ways to sequence the genome or DNA, store and evaluate the information obtained. Some of the methods are Sanger and Next Generation Sequencing, also known as hierarchical and…

Perinatal counseling needs related to genetics are very important for patients and their families at risk of having a child with genetic disease of birth defect. Wherein, the need to describe the use of genomics to patients and families is paramount, they need to understand that genomics study genes, which is considered as the basic units of inheritance and because it influences all body part, an error one of the genes could lead to genetic disease (McCance & Huether, 2014). In the article “…

During its lifetime all living organisms are subjected to a number of factors threatening the integrity of their DNA. Organisms have evolved to efficiently respond to these DNA insults that result from either endogenous sources (cellular metabolic processes) or exogenous sources (environmental factors). Endogenous sources of DNA damage include hydrolysis, oxidation, alkylation, and mismatch of DNA bases; sources for exogenous DNA damage include ionizing radiation (IR), ultraviolet (UV) radiation…

In this study, we analyzed the bulk of genomic and transcribed CsRn1 sequences encompassing the putative frameshift region in C. sinensis and Opisthorchis viverrini, which is a nearest phylogenetic neighbor of the liver fluke, to address the issue regarding the expression strategy of CsRn1. Our results demonstrate that CsRn1 copies lacking frameshifting have arisen from the precedential counterparts with two overlapping ORFs by a single-nucleotide insertion at an upstream region of gag stop…

Chromatin Immunoprecipitation and Sequencing (ChIP-seq) of Heat Shock Factor (HSF) Temporal Binding Sites during the Critical Period of 8-12 Hr After Egg Lay (AEL) in Drosophila melanogaster Embryogenesis Background Heat Shock Response was discovered by the Italian scientist Ferrucio Ritossa, when he saw puffs in the Drosophila polytene chromosome on inducing them with heat. It was later discovered that this Heat Shock Response was regulated by a transcription factor called Heat Shock Factor…

1.Describe one of the cattle breeds that are found on the Dickenson farm. Why is Ohio a good place to raise the breeds shown in the video? Longhorns are a type of cattle that are grown in the United States. As their name suggests, they have long horns. Grass is an essential food to longhorns. Ohio has healthy grass that will be wonderful for the longhorns. 2.How did the J & N Ranch change their cows? Why did they do this? The J & N Ranch changed their cows color to black by breeding them…