Genomics

Chromatin Immunoprecipitation and Sequencing (ChIP-seq) of Heat Shock Factor (HSF) Temporal Binding Sites during the Critical Period of 8-12 Hr After Egg Lay (AEL) in Drosophila melanogaster Embryogenesis Background Heat Shock Response was discovered by the Italian scientist Ferrucio Ritossa, when he saw puffs in the Drosophila polytene chromosome on inducing them with heat. It was later discovered that this Heat Shock Response was regulated by a transcription factor called Heat Shock Factor…

scientific discovery. Genetics is a huge interest of mine so I completed an online course-The Genomics Era by St George's Hospital. I took a lot from the experience, I enjoyed interacting with other like-minded individuals through discussions and discovered a passion for genetic testing, consequences of genetic mutations and cancer genomics. The course forced me to also consider the ethics of various genomic collection methods which I'd previously overlooked and I saw the difference I could make…

using SDS-PAGE and found it has a size of about 53-kilodalton (kDa). The location of the TP53 gene is at chromosome 17, at position 13.1. [11]. TP53 has 393 amino acids. TP53 has many important functions in the body. These functions play a role in genomic stability, apoptosis, and inhibition of angiogenesis. TP53 can be active and will respond to the exposure of toxic metals,…

gene function analysis. These questions pose to look at what the genetic basis of dissociation between mosses and their microbes is. His lab is currently focused on two projects: the evolutionary causes and consequences of dioecy and the community genomics of moss-associated nitrogen fixation in a changing Arctic. These questions are important because the maintenance of separate sexes (dioecy) is, as said by Dr. McDaniel, “an enduring evolutionary puzzle.” These questions and research projects…

Norwegian, Dutch and Icelandic peoples, in other races have more common. (1) Considering the harmful BRCA1 and BRCA2 are rare in most of racial/ ethnicities populations who Expert think should undergo genetic testing. Most scientists believe that genomic testing should not implement on everybody and it is better to carry out only to those people who have a family history of breast or ovarian cancer. (1) The possibility that someone with background of having a family member inherited the…

hope people with positive mutation never have breast cancer and importantly they showed breast cancer at the old age. Moreover, considering that harmful BRCA1 and BRCA2 mutations are rare in most racial/ ethnic populations. Most experts believe that genomic testing should not be implemented on everybody and it is better to carry out only on those people who have a family history of breast or ovarian…

Diagnosis of Neurofibromatosis type 1 is based mainly on clinical findings which meet the diagnostic criteria for Neurofibromatosis 1 which was developed by the National Institutes of Health. Since Neurofibromatosis 1 is caused by heterozygous pathogenic modifications in NF1, molecular testing is rarely needed for diagnosis, and is only useful for certain individuals. The diagnostic criteria for Neurofibromatosis 1 is: 1 they must have six or more café-au-lait macules which are, for prepubescent…

for crime scene investigations. People can now trace their family tree beyond the family bible or old courthouse documents. This also tells ones genetic makeup, which helps to determine risk and predisposition to certain diseases. Stem cell and genomics are steadily progressing from that strange double helix thing students had to put together in Science…

cure, genomic studies into understanding cancer have become a central focus of cancer research. The complexity and variability in mutational drivers of cancer have made it hard for researchers to derive a ‘cure-all’ solution for a single type of…

A body is made up of cells, and in each cell, genes are found. Genes are passed down to children from parents, and over time genes can mutate. Mutations, or changes, in genes acquired from a mother or father, or genes damaged throughout a person’s life, is what contributes to the growth and development of cancer. Normally, one mutation will not cause cancer because the human body can correct that change, but with a multitude of mutations over time cancer becomes more probable. There have also…