BRCA2

The protein I have found from my DNA sequence is BRCA2. BRCA2’s official name is “breast cancer 2, early onset.” The gene mutation that can occur is breast cancer susceptibility. BRCA2 is a protein coding gene. The gene makes a protein that acts as a tumor suppressor. This helps to prevent rapid or uncontrollable growth of cells. BRCA2 also helps to repair damaged DNA. It helps to maintain stability of a cell’s genetic information. When this gene is mutated, it can cause an increased risk of breast cancer in either males or females. It is equally inherited from men or women and can be just as common in males as in females. The mutations can be passed on through the generations and are present in every cell in the body. Just because a person…

BRCA1 and BRCA2 genetic testing, should everyone do it? Introduction Cancer happens when the cells in the body grow out of control and make tumors. This procedure is organized by biochemical in different parts of the body. (7) Breast cancer is the most common cancer among all the woman and about 5-10 percent of breast cancers are heritable. (9) Mutation in BRCA genes is responsible for 25 percent Inherent Breast cancer. Breast cancer is affected by so many risk factors. Every year about 233,000…

BRCA2 is a gene that provides instructions for a protein that acts as a tumor suppressor. The tumor suppressor prevents cells from growing and dividing too quickly. If there is a problem or mutation with this gene it will not work as effectively and would allow cells to produce a tumor. The BRCA2 protein helps to repair damaged DNA. It works by combining with other proteins to fix breaks that may occur in other cells. The official name of BRCA2 is breast cancer 2 – early onset. This is due to…

BRCA1 and BRCA2 genetic testing, should everyone do it? Shahrzad Eslamian Purpose: For a person with a positive mutation in BRCA1 or BRCA2, the chance of getting breast cancer increases by 50-60 percent.1 This causes concern for some women and makes them take a BRCA1/2 mutation test to make sure they are not carrying this mutation. In September 2015, a research from UCLA was published that indicated some debate over whether or not testing BRCA genes is worth the cost.4 This paper will be…

The transformation of these proteins result in genetic malformation that can lead to cancer. It is recommended that anyone that have a family members with a mutation in BRCA1 or BRCA2 to be tested since it increases their risk of cancer (National Cancer Institute). In this case, Mrs. Allen has been tested positive for BRCA1 and she is also going into breast cancer treatment. In this situation testing Lindsay will be beneficial and necessary since she is at significant risk of developing breast…

The tests can be performed on a blood or saliva sample. BRCA testing is a genetic test that looks at the sequence of the BRCA1 and/or BRCA2 genes. This test examines the BRCA1 and BRCA2 genes and looks for key mutations. Changes in their genetic code indicate increased cancer risks. The BRCA1 and BRCA2 are genes that produce tumor suppressor proteins. These proteins aid in repairing damaged cells. When these genes are mutated, cell damage is not repaired properly. These mutated cells are…

A diagram of this process is shown on page 5. Symptoms usually do not appear until the cancer has spread to the pelvis and stomach. Sadly, many cases are detected when the cancer has already advanced in later stages. The most common symptoms are loss of appetite and unexplained weight loss. Other symptoms include bloating, changes in bowel movements, indigestion in the gastrointestinal region. Because of the spread of tumor cells, women may feel pain and have fluid and lumps on the stomach.…

In the afterword, Skloot discusses the commercialization of human tissue, the patents on various genes, and the fact that the companies who own the patents dictate what research is done on the genes. This is troubling for the reason that it limits the time in which scientists find a cure the genetic disease. One, in particular, is Myriad Genetics, the owner of the license for the BRCA and BRCA2, which is the main cause of breast and ovarian cancer. Skloot exposes her distaste for the unethical…

Ovarian Cancer is an adult onset genetic disease that is often fatal. This type of cancer occurs when cells in a female’s ovaries grow abnormally and too many cells are produced. The cancer cells can then spread to other parts of a woman’s body (Cancer.net, 2016). The ovaries, located on either side of the uterus, are two small almond shaped glands that produce the female hormones, estrogen and progesterone. The ovaries also release eggs during a woman’s years of reproduction, starting with her…

ever come back, which can be true in some cases. In some cases, other treatment options would work just as well as a mastectomy and they wouldn’t have to have the complex surgery. It all depends on the type of cancer and how aggressive it is. When women are diagnosed with breast cancer in one breast that is not very serious and not very aggressive, they shouldn’t have to worry about the other breast. However, many women think that the odds of developing a form of deadly cancer in their other…