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    BRCA1 and BRCA2 genetic testing, should everyone do it? Shahrzad Eslamian Purpose: For a person with a positive mutation in BRCA1 or BRCA2, the chance of getting breast cancer increases by 50-60 percent.1 This causes concern for some women and makes them take a BRCA1/2 mutation test to make sure they are not carrying this mutation. In September 2015, a research from UCLA was published that indicated some debate over whether or not testing BRCA genes is worth the cost.4 This paper will be reviewing the evidence from Dr. Ganz et al. about the breast cancer testing. In addition, this paper contains some other research related to the topic, including my own research and perception. Introduction Cancer happens when the cells in the body grow…

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    Ovarian Cancer

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    The tests can be performed on a blood or saliva sample. BRCA testing is a genetic test that looks at the sequence of the BRCA1 and/or BRCA2 genes. This test examines the BRCA1 and BRCA2 genes and looks for key mutations. Changes in their genetic code indicate increased cancer risks. The BRCA1 and BRCA2 are genes that produce tumor suppressor proteins. These proteins aid in repairing damaged cells. When these genes are mutated, cell damage is not repaired properly. These mutated cells are…

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    BRCA2 Genetic Testing

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    BRCA1 and BRCA2 genetic testing, should everyone do it? Introduction Cancer happens when the cells in the body grow out of control and make tumors. This procedure is organized by biochemical in different parts of the body. (7) Breast cancer is the most common cancer among all the woman and about 5-10 percent of breast cancers are heritable. (9) Mutation in BRCA genes is responsible for 25 percent Inherent Breast cancer. Breast cancer is affected by so many risk factors. Every year about 233,000…

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    Myriad Genetics

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    include “American Civil Liberties Union” it becomes a fact and therefore justifies bringing it to court and her writing. She also incorporates “breast cancer survivors” to add emotional appeal to the passage as it indicates that the multiple survivors who agree they were overcharged for their medical expenses. Skloot’s inclusion of this depicts Myriad as a company who takes advantage of people with cancer this is to provoke the audience. Without the patent researchers might have been able to…

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    Ethical Issues in Genetic Screening for Breast Cancer: Patenting of BRCA 1 and BRCA 2 genes Breast cancer affects over 508,000 women worldwide and almost 50-58% of cases result in death. It is the top cancer in women (WHO, 2017, p.2). Scientist Mary-Claire King discovered BRCA1, the gene mutation for causing breast cancer, in 1994. BRCA2 was discovered in 1995 (Park, 2014). Testing options have previously been limited due to gene patenting. A patient carrying BRCA 1 or BRCA 2 can reduce the…

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    I feel qualified to hold this position because of how influential the big/little aspect of Zeta has been on my life. My family within Zeta is so close from my great grand big down to my little, and each of them have given me a feeling of having a home away from home. I’ve experienced how important getting a big sister can be when you are a freshman trying to find your way and find where you belong at Auburn. I’ve also experienced how important it is to turn around and be that same guiding light…

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    0703 Instituto Mário Penna: Don`t count on luck Mario Penna Insitute is a humanitarian institution founded in 1971 at Brazil. It is constructed by two hospitals offering about 400 hospital beds. One of hospital is named Minas Gerais CACONs, which is the largest provider of cancer care in the state, serving abundant complex cancer cases. “Don’t Count on Luck” is the campaign that Instituto Mário Penna holds for increase awareness of breast cancer. The campaign is using series of poster to…

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    Ovarian Cancer Case Study

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    Technology is very important in human society and become inseparable with people’s life. There are still a huge number of people who begin to use technology every day and quickly increasing. Majority of people no matter in school or at work are using cellphone and laptop for wither class or work. The vitality of technology would give people different method of use and one of the most important function is communication. One of the most useful technology product “internet” is use to spread out…

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    ancestry. Ashkenazi Jews have a higher risk of BRCA1/2 gene mutation at 1 in every 40 women, compared to the general population excluding Ashkenazi Jews at 1 in every 400 women (Petrucelli et al, 2013). Most breast and ovarian cancers have no known cause, and very few are a result of HBOC. Less than 1% of the population has mutations that lead to HBOC, and only 5-10% of women with breast cancer and/or ovarian cancer have a mutation in their genes. There is also a greater risk of developing…

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    Lynch Syndrome Essay

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    syndrome the pathologist should first apply IHC for MLH1, MSH2, MSH6 and PMS2 (Figure 3), that is extremely reliable, then request microsatellite instability analysis by PCR. Hereditary Breast and Ovary Cancer Syndrome is due to germline mutations in breast cancer 1 (BRCA1) and BRCA2 genes. These germline mutations cause about 5-10% of all ovarian carcinomas and a small minority of endometrial carcinomas. Specifically, women with mutated BRCA1 and BRCA2 have a 40% and a 20% lifetime risk to…

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