Genomics

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    we will retrospectively test the application of selected biomarkers in PDAC diagnosis, treatment evaluation and disease prognosis. As biomarkers could be in the form of genomic abnormalities or transcriptional aberrations, corresponding methods will be used for validation, which we have previously reported (118-120). The ultimate objective is to develop biomarker detection protocols for cost-effective and non-invasive detection of clinical PDAC in a highly sensitive and specific fashion. Genomic PCR will be tested extensively as a convenient and preferred tool for detecting biomarkers of genomic abnormalities. After confirmation on ex vivo expanded CTCs, optimal PCR settings will be established and tested for detection of CTCs directly from blood samples, first from the blood of mice…

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    testing, risk factors, and aiding in prevention. All of these factors influence healthcare and patients. Each person can find out if they are at risk for diseases, which can lead to preventative measures. For example, “tests have been developed to detect mutations for a handful of more complex conditions such as breast, ovarian, and colon cancers” (Human Genome Project and Beyond). This can influence a person’s life if they have family members with these genes by knowing what and how they can…

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    accordingly to target that specific mutation. The proliferation of bioinformatics and computational genomics plays a pivotal role in making this incentive effective. From extracting the raw data of DNA to understanding the genetic variations and clinical indication of these information, bioinformatics is leveraging these implications towards creating the personalized…

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    “Through my research I am trying to better understand differences between genetic predisposition and lifestyle factors for type 2 diabetes,” Flowers said. “I also look at how to optimize risk prediction and prevent type 2 diabetes for high risk racial groups.” Flowers lab is a mixture of a dry lab and a wet lab and she collaborates with other faculty members. One faculty member she collaborates with often is Kord Kober, PhD, who is another UCSF genomic laboratory lead. They both manage and…

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    Myosin: Genomic Analysis

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    Myosin are a large superfamily of motor molecule which is move along cytoskeletal filaments and interact with actin filaments. That movement requires huge amount of hydrolysis ATP molecules to change the conformation. The genomic analysis thirteen different members of the myosin gene. In addition, the most present myosin type in all eukaryotic cells are: myosin I and myosin II. On the other hand, the less present type of myosin is myosin V. Also, myosin can be divided to two class; conventional…

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    The fields of genetics and genomics have made significant strides in the past ten years, and researches are applying the results of research to many areas of health care. Because disease risk and health conditions are influenced by elements of environment, lifestyle, and genetics, the nurse needs to consider these factors when assessing families for genetic risks (Williams, Cashion, Shekar, & Ginsburg, 2016). The nurse uses the information gathered from a family health history to identify…

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    Genomics in Patient Assessment Subtopic and a Summary of the Journal Subtopic: How genomics affects nurse’s physical assessments Summary This journal article delves on genetic testing and the appliance of genomics in health care. Further, the article expounds on the various appliances of genetic testing and why it may result in better health outcomes (Badzek, Turner, Jenkins, 2008). For instance, through genetic testing, families can successfully evaluate the predisposing ailments in their…

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    The study of inheritance at the at one of the smallest levels is referred to as molecular genetics and is utilized for many purposes, which include genes, genotyping, sequencing, cloning, etc. (Kelly, 2016). This allows for the ability to conduct DNA analysis revealing varying compositions and properties. For the following experiment the genomic DNA from Drosophila melanogaster, was utilized to be cloned and sequenced for either actin or 18s rRNA. In order to clone and sequence the specific…

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    Learning information in class engaged and interested me throughout my academic career; however, the opportunity to discover new information through research is one of my most intellectually stimulating experiences. With my goal to learn as much as possible under Dr. Nolan Kane, the Professional Investigator of the Cannabis Genomic Research Initiative (CGRI), I have expanded my traditional bench lab experience to bioinformatics, hemp breeding, and leading designing and performing my own project…

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    This week’s readings have to do with race and genetics in correlation with biomedicine. In Troy Duster’s Race and Reification in Science, he talked about the ability to use genomic knowledge and apply it to the pharmaceutical field. Anne Fausto-Sterling’s The Bare Bones of Race talked about, the racial difference in bone density and uses and definitions of race in medicine. Joan H. Fujimura, Troy Duster, and Ramya Rajagopalan’s collective piece, Special Issue on race, Genomics, and Biomedicine,…

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