Hypertrophic cardiomyopathy (HCM) is the second most common form of heart muscle disease and is the number one cause of sudden cardiac death in young athletes. It affects approximately one in 500 adults in the United States. HCM is a genetically determined heart muscle disease caused by more than 1400 mutations in 11 or more genes encoding proteins of the cardiac sarcomere (Maron & Maron, 2013). HCM is characterized by left ventricular hypertrophy (LVH) of various morphologies with a wide array of clinical manifestations and hemodynamic abnormalities. The age when symptoms develop, the severity of symptoms, and the long-term prognosis of a person diagnosed with hypertrophic cardiomyopathy vary with each individual. Treatment of HCM focuses on relieving the symptoms and decreasing the risks associated with HCM. For many patients diagnosed with HCM,…
Introduction / 5p- 1200w The most frequent cause of sudden cardiac death is hypertrophic cardiomyopathy (HCM), mainly in young people. It is characterized by thickening in the left ventricle (LV) wall not related to load condition such as aortic stenosis or systemic hypertension (Bing, Knott et al. 2000). It is estimated that approximately one in 500-1000 population. HCM is a complex genetic inherited cardiovascular disease caused by dominate mutation in coding of cardiac sarcomere proteins gene…
I am often asked why I cannot have a cup of coffee following major heart surgery, which repaired a heart defect called Hypertrophic Obstructive Cardiomyopathy, or HOCM for short. I find that if I tell someone that I cannot have coffee, I am often met with disbelief, arguments on why I should have coffee, laughter, or even as far as waving a perfectly scented cup of lovely coffee under my nose. However, after everything I have been through concerning my heart, I will not succumb that easily to…
She was intubated and hooked up to a machine that breathed for her. After she was somewhat stabilized they ran an infinite amount of tests to try to figure out what was going on. The doctors finally reached a decision and diagnosed her with hypertrophic cardiomyopathy or HCM for short. HCM is a hereditary heart disease that causes a thickening of the heart. It slowly develops over time and makes it harder and harder for the heart to squeeze and release correctly. HCM is often found in athletes…
Hypertrophic cardiomyopathy (HCM) is the most common form of feline cardiomyopathies. This disease affects the cardiovascular system. The heart has many important anatomical features. One of these being the ventricle of the heart. The ventricle of the heart is the main heart muscle that pumps blood. When HCM occurs the left ventricle within the heart thickens. When the thickening of the ventricle occurs there will be a decreased ventricular chamber volume, and abnormal ventricular relaxation.…
What is it? Cardiomyopathy is a term to describe a disease that affects the muscles of the heart. Cardiomyopathy occurs when the muscles of the heart become stiff and enlarged and it makes it difficult for the heart to pump blood. In response, it may cause heart failure and the weakened heart will be able to pump blood causing blood to flow inadequately into the lungs and other areas of the body. There are three main type of cardiomyopathy, which are dilated cardiomyopathy, hypertrophic…
Dilated cardiomyopathy, is “a form of heart disease that weakens the cardiac muscle, preventing the heart from pumping blood efficiently” (“Duchenne and Becker Muscular Dystrophy”). Patients who have Duchenne disease will develop cardiomyopathy and have a lesser life expectancy due to heart failure. Also, with the vast amounts of blood loss and the weakened muscle tissue replaced by fat, it is also a main factor of death for young patients of DMD. According to Barp, “...had led to a greater…
flow by 11% and the GFR by 12% but the use of milrinone did not provide any benefit in diuresis of ADHF. (7) In this study, we collected the data of patient who heart failure and on inotropes and we compared the renal functions before and after the inotropes and the aim of the study was to answer the question: do inotropes improve renal function or not? Methods: Study design and patients: It is a retrospective study of 250 patients who were seen in our hospital center from 2011 through 2016.…
Cardiomyopathy is a type of cardiovascular disease that is usually asymptomatic. It is a general term used to describe a diverse group of diseases that affects the heart muscles. For most people with cardiomyopathy, their hearts don't function normally because their heart muscles have become either enlarged, abnormally thick, abnormally rigid, or unable to transmit electrical impulses in a normal fashion. Because cardiomyopathy is a general term, there are different types. Some of the major…
Cardiomyopathy is a disease of the heart muscle. In cardiomyopathy, the heart muscle becomes enlarged and rigid. As this disease worsens, the heart becomes weaker and is less able to pump enough of blood for the body. Cardiomyopathy can be inherited from your parents or close relatives, due to a change in some of the genes in heart muscle proteins. It can also be acquired over time as a result of smoking, diabetes, high blood pressure or some other disease or condition. Cardiomyopathy can lead…