160116 Duchenne Muscular Dystrophy “Muscular dystrophy (MD) is a genetic disease characterized by progressive weakness and degeneration of the skeletal or voluntary muscles which control movement” (Muscular dystrophy, 2013). Muscular dystrophy is classified into nine major types that each affect specific muscle groups, certain age groups and are identified by different signals. Duchenne muscular dystrophy most commonly affects males and is targeted at younger children (Facts about Muscular Dystrophy, 2015). “The Centers for Disease Control and Prevention estimated that 1 out every 5,600 to 7,700 males between the age of 5-24 has DMD” (Seiner, Duchenne Muscular Dystrophy). Description: A French neurologist Guillaume Benjamin Amand Duchenne…
Duchenne Muscular Dystrophy Duchenne Muscular Dystrophy is a disorder in which a person experiences progressive muscle degeneration and weakness. This genetic disorder is an X-linked recessive chromosome disorder or can be caused by mutations when the parents genes are copied into the child's cells. It is one of nine types of muscular dystrophy (Duchenne Muscular Dystrophy, 2016) and is the result of the absence of dystrophin, a protein needed for muscles to function properly. Duchenne Muscular…
Duchenne Muscular Dystrophy In this world, there are many diseases that are being caused by the X chromosomes or the Y chromosomes. Some of the diseases could be passed down from generation onto the next because it is gene and some of the diseases can be treated and which later on causes for it to make it worse. The diseases that would always be there would be Down Syndrome, Huntington’s Disease, Hemophobia, and many more. As you can see, this paper is going to be able a genetic disease that is…
Duchenne Muscular Dystrophy is a genetic disorder that is characterized by progressive muscle degeneration and weakness (DMD). A French neurologist, Guillaume-Benjamin-Amand Duchene was the first to describe Duchenne Muscular Dystrophy in the 1860s and this is one of the known nine types of muscular dystrophy. The milder version of Duchenne Muscular Dystrophy is the Becker Muscular Dystrophy (BMD). Becker Muscular Dystrophy is less predictable than the DMD and it is a lot slower. While Duchenne…
Introduction Duchenne muscular dystrophy, or DMD, is the most common and severe type of muscular dystrophy, caused by a genetic disorder that leads to progressive muscle weakness and degradation (Marieb & Hoehn, 2015). DMD is a recessive sex-linked disease and is often inherited through the mother. Because this condition is enacted by a mutation of the X chromosome, it is expressed almost exclusively in males, with one in every 3,600 males affected worldwide (Marieb & Hoehn, 2015). The DNA…
The protein that was concluded was dystrophin. The disease that is associated with this protein is Duchenne. Duchenne is referred to as DMD and is associated with muscular dystrophy. DMD is one of the most common gene malfunctions and is causes by having a problem with a gene which makes up the dystrophin protein. Gupta (2014) explained that when the protein is functioning properly, muscle cells are able to keep their shape and strength, but without it they can begin to break down and become…
Duchenne muscular dystrophy is progressive disease of the muscle, caused by defective or absent glycoprotein, dystrophin, in the membrane of the muscle wall. Dystrophin reinforces the myotube membrane skeleton by increasing its stiffness, thus a lack of dystrophin causes substantial reduction in muscle stiffness. Symptoms include ambulation difficulties, hyperopia and gross motor milestone delays in infants and children, calf hypertrophy, an imbalance in lower limb strength, and diminished…
Duchenne muscular dystrophy (DMD), the most common form of all muscular dystrophies, is an X-linked disorder affecting approximately one in 5000 newborn boys. "(page1; paragraph 1; lines 1-4)" Patients are usually restricted to a wheelchair around the age of twelve and facing death somewhere between the ages twenty-five to thirty. DMD is caused when the dystrophin gene is mutated. That mutation stops the communication for a functional protein. The inadequacy of dystrophin causes muscle fiber…
1. Description of the chosen disability. Duchenne muscular dystrophy (DMD) is a progressive genetic condition that causes skeletal and heart muscles to breakdown leading to difficulties in mobility and walking (Muscular Dystrophy Australia [MDA], 2015, para. 1). DMD predominantly affects males with approximately “…one in 3500 live male births throughout the world” (MDA, 2015, para. 1). According to Emery, Muntoni, and Quinlivan (2015, p. 31) the most common concerns from parents with children…
Abstract: Duchenne Muscular Dystrophy (DMD) is a X-linked recessive condition in which a defective gene called dystrophin is inherited. Dystrophin is an essential protein for muscular strength and stability. DMD affects 1 out of 3600 males and the symptoms are more severe in males than in females. Symptoms of DMD include skeletal deformities, fatigue, learning and intellectual developmental delay, difficulty breathing, and heart disease. Diagnosing DMD is done through serum CPK, muscle biopsy,…