Doxorubicin

Diet tips on improving stomach cancer life expectancy Description: When one is diagnosed with cancer, he/she worries about stomach cancer life expectancy. Exercising control over the diet and following the diet prescribed by your physician can in some way improve life. Among all the diseases, gastric cancer is the 4th most common ailment. People over 55 years of age are more susceptible to getting stomach cancer. Poor dietary habits can increase the risk of stomach cancer but then following certain diet tips can improve the stomach cancer life expectancy to some extent. Once anybody is diagnosed with stomach cancer, there is lot of things to do. The doctor will prescribe a treatment plan and in fact the patient can try to improve his life with the proper diet. Consuming Quercetin rich diet It is important to include food rich in Quercetin since it is the bioflavonoid that has anti-bacterial, anti-fungal and anti-cancer properties. Red and yellow onions have high content of bioflavonoid which is very healthy for the patient. Avoid protein intake Pancreatin is the leading weapon fighting against cancer. Being the mixture of protein-digesting enzymes, they can fight cancer. But if one consumes a protein rich diet, the Pancreatin enzyme will keep digesting the protein. Hence, it will not have any time to combat cancer. A protein free food is highly recommended. Include Curcumin in the diet Curcumin is the photochemical that imparts yellow color to turmeric. It has great…

Cancer is one of the most important human health problems in the world. There is a global effort to make progress in new technologies that could overcome the inherent disadvantage of chemotherapy and efficiently destroy tumors without damaging the healthy body. The two most important goals of antitumor therapy are to detect cancer at primary steps, deliver medicinal active ingredients to the special sites with reducing of adverse effects and increase of the efficacy of an anticancer drug. One of…

Introduction Doxorubicin, an anthracycline antibiotic, is commonly used as an effective antineoplastic agent, in the treatment of various of malignancies, including leukemia, lymphoma, and solid tumors. Unfortunately, the clinical use of this drug is limited by cumulative dose-dependent cardiotoxicity, which may cause irreversible and severe effect of cardiomyopathy [1] The specific mechanisms of doxorubicin (DOX) induced cardiotoxicity are complex and although decades of research on this drug,…

penetration of the BBB by transcytosis. The Tet-1 peptide (amino acid sequence H-L-N-I-L-S-T-L-W-K-Y-R), was discovered by phage display and has affinity and cellular processing similar to the heavy chain of the Tetanus Toxin (TTC). Tet-1 peptide binds to trisialoganglioside clostridial toxin (GT1b) receptors, has affinity to neurons and retrograde transportation (from distal axonal projections of neurons to the cell body) properties so as order to facilitate targeting of the therapeutic agent…

plants has been proposed as the major factor for the low breast cancer incidence in populations. Chemotherapeutic drugs for breast cancer are given alone or in combination based on type, age and stage of cancer. Some of the drugs for early and metastatic breast cancer are doxorubicin, rapamycin, tamoxifen, cyclophosphamide, docetaxel, transtuzumab (herceptin), pacillitaxel, carboplatin, gemcitabine, vinorelbine, methotrexate etc. 1.2 RESVERATROL: Resveratrol (trans-3, 4’,…

assay. Moreover, compounds were tested for their possible effect on the reduction of the proliferation of leukemia cells. Compound 3, 5, 8 and Doxorubicin showed a positive effect. In this experiment, a serial dilution of compounds that was compounds diluted in the ratio of 1:10 to get various concentrations of 0.002µM, 0.02µM, 0.2µM, 2µM, 20µM, and 200µM was tested with the optimal number of cells. This was used to determine at which concentration of the compounds would reduce 50% of the…

mL of 0.4 M HCl. The Fe salts solution was added dropwise into 200 mL of alkaline solution with pH>12 under stirring vigorously in an inert atmosphere. The obtained colloid solution was centrifuged at 10000 rpm, washed with deionized water and dried under vacuum for 6 h at 60 °C. A black fine powder (Fe3O4) was achieved. Preparation of doxorubicin hydrochloride loaded nanocomposites Doxorubicin was used as a model drug in drug loading and release tests. The DOX-loaded Poly…

agent of concern. Trastuzumab is found to inhibit the Her2 expression ultimately inhibiting the malignant transformation of the cancer cells working at the DNA level preventing cancer cell growth and proliferation. At the same time, this is detrimental to the myocardium as ErbB2 signaling has a vital role of maintaining left ventricular function. This chemotherapy agent is believed to inhibit the ErbB2 for Her2-positive breast cancer tumors while also inhibiting the cardiac signaling…

Sometimes gives this treatment as a single dose in the operating room, right after surgery to remove the cancer. This approach is called chemotherapy hot spot. Most often used to treat cancers peritoneum, in this case it may be called chemotherapy in warm water or HIPC. Chemotherapy drugs used for mesothelioma You can use many chemo drugs for treatment of mesothelioma, including: Bimitriksid (Alimta ®) Sisblatine Karboblatin Gimsitabini (Gemzar ®) Methotrexate Vinorilbini Mitomisin Doxorubicin…

There is a strict monitoring that takes place during this time. Liver function, blood cell counts, heart function, serum electrolytes and creatinine, and fluid retention are needed so that the oncologist can track the progression of tumor cells and their response to the drug. Once this is done, the oncologist can then decide if the treatment needs to continue in the same way, be modified, or be terminated all together. It is recommended by doctors to premedicate with corticosteroids before…