further from each other because they have higher kinetic energy. Therefore, the further the phopholipid between each other, the fluidity the membrane is. Besides that, fatty acids of the lipid that composed of saturated hydrocarbon tend to have straight shape so it will pack more tightly. The double bonds in unsaturated fatty acids will make the lipid molecules are less straight and more loosely packed so that it will become more fluid while in saturated tend to have straight shape because each…
actually use it to maintain the structure of our bodies? Our bodies break down the nutrient into amino acids, which are just smaller molecules. While I recommend complete protein supplements, there are also amino acid supplements that focus on a few of the more used amino acids. Many top athletes use whey powder supplements…
Particularly, several studies were initiated to unravel the structural basis for the observed allosteric, substrate-dependent stimulation of SIRT1 activity by the stilbenoid RES. In this regard, a crystal structure of SIRT1 in complex with RES and a 7-amino-4-methylcoumarin (AMC)-containing peptide provided valuable structural insights into the regulation of SIRT1 activity by RES (34). In the proposed model, each SIRT1 can bind to three RES molecules (Figure 5A). Two of these RES molecules make…
Monocistronic mRNA Coupled transcription-translation possible Not possible Linearly polyribosome Circular polyribosome No cap on mRNa 5’end of mRNa recognized by the cap Start codon is next AUG after ribosome biding site No ribosome binding site First amino acid is formyl-Met First Met is unmodified 70S ribosomes (30S and 50S subunit) 80S (40S and 60S) Small 30S : 16S rRNA and 21 proteins Small 40S : 18S rRNA and 33 proteins Large 50S: 23S and 5S rRNA plus 31 protein Large 60S : 28S, 5.8S and…
Introduction Nucleotide is a building block for deoxyribose nucleic acids which is called DNA that has four base units,adenin(A) ,thymine(T) ,guanine(G), cytosine(C). The nucleotides can bond with their base pairs(A=T,G=C) to form a linear strand that is supported by sugar-phosphate backbone. In the linear strand, some of three base sequence is a codon and each codon is related to an amino acid. These codons come together in a linear sequence and create a gene. Gene can be called as cipher that…
Result and Discussions 3.1. Changes in catalytic pocket Instead of having the conventional catalytic triad residues (His665, His667 and Asp767) in it’s protease domain, Lon protease employs the Ser679 – Lys722 catalytic dyad to form a catalytic pocket for promoting proteolysis. But the mutations in catalytic dyad residues make some changes in the catalytic pocket of these three mutant types. A comparison of SASA values and RSA values [Supplementary file 1] were done among the catalytic…
4.3. The third dsRBD of Xlrbpa (xl3) is a protein/protein dimerization domain The strongest interacting partner from a two-hybrid screen with Xlrbpa turned out to be Xlrbpa itself. Two-hybrid assays with deletion constructs together with coimmunoprecipitation experiments identified xl3 but neither xl1 nor xl2 as a dimerization domain (Fig. 18, 19 and 20). Xl3 enhances the PKR antagonistic ability of Xlrbpa as previously indicated and discussed. The third domains of PACT and RAX, the human and…
Introduction Osteogenesis imperfecta describes a group of genetic disorders that are colloquially known as “brittle bone disease” and is estimated to affect around 7 out 100,000 people around the world. As the name suggests osteogenesis imperfecta is characterized by imperfect formation of the bones that leads to frequent fractures or breaks from minor trauma (Rauch et al., 2004). Depending on the severity of symptoms the impact to an affected individual 's life can differ. This paper will…
gov). Amino Acids are the building block of protein. Amino acids bond together to make long chains, which is protein (nlm.nih.gov). Human body uses amino acids to make proteins to help the body break down food, repair body tissue, grow, and perform many other body functions (nlm.nih.gov). Amino acids can also used as a source of energy by the body (nlm.nih.gov). According to what I learned in Bioorganic lecture, the amino acid structure contains a carboxylic acid group (-COOH) and an amino group…
shape? This experiment is going to test which additives make gelatin stronger. In learning about this project, there were many new terms in the sources used. Some of them will be discussed in this paper (gelatin, collagen, protein, tensile force, amino acid, triple helix, collagen fiber, and tensile strength). Gelatin is a protein food gotten by adding water to collagen, the most common animal protein. (Jiggle it:…