strong acid. Then, react one of the unknown solution with all of the others and note any visible reaction (change in color or formation of precipitate) that occurs. After that, some the solutions might be identified throughout the…
Nimodipine 0.02% solution contains the following excipients:
Ethanol 96%, Macrogol 400, sodium citrate, citric acid, Water for Injections Ph. Eur.
These excipients consist of properties that aim towards the proper functionality of Nimotop. They consist of inherent stabilities that cause little or no effect in the stability of the drug and they do not have any acute or chronic toxicity. The excipients are also added into the Nimodipine 0.02% solution to enhance the biological…
CHEM 1252 L
Exp 12: Thermodynamic Analysis of Chemical Equilibria
The reaction being done with borax and HCl is an acid base reaction. The K constant expression of the reaction is Kc = [Na^+][B4O7^-2]. A titration is needed for this experiment because when a strong acid with a known concentration is added to a weak base, the unknown concentration of the weak base can be found, which can then find the moles of the weak base, which can then find the Kc. The first law of…
Caprolactam (CPL) is an organic compound with the formula (CH2)5C(O)NH. This colourless solid is a lactam or a cyclic amide of caproic acid. Caprolactam was first described in the late 1800s by Gabriel and Mass, when it was prepared by the cyclization of ε-aminocaproic acid, the product of the hydrolysis of caprolactam.
In the months after Schlack’s discovery the first stocking were produced from Perlon. All the Perlon produced went to the war effort.…
Determination of λ max
Gemifloxacin mesylate λ max is determined by preparing one standard concentration of 10μg/ml and scanning should be done.
Preparation of 0.1N HCL
8 ml of hydrochloric acid is taken in 1000ml volumetric flask and dissolved with distilled water and then make up to 1000ml with distilled water.
Standard graph of Gemifloxacin mesylate:
The λmax of Gemifloxacin mesylate in 0.1N HCL was scanned in UV-Visible Spectrophotometer and found to have maximum…
Preparation of polyallyl polyether of allyl sucrose
Allyl sucrose is prepared by using sucrose, allyl chloride, NaOH and DMSO. This novel method is less time consuming and required less solvent than other methods. The product is characterized by Fourier Transform Infrared (FT – IR), 1H-NMR and MASS Spectrometer. Key words: allyl sucrose, allyl chloride, sucrose
Allyl sucrose is used for…
solution, because it is the source of the Grignard reagent. Because the halide cannot be eliminated, the next best option is to minimize the amount of halide in the reaction. In this experiment, a small concentration of the halide is reacted with a high concentration of magnesium to ensure maximum contact between halides and magnesium. To do this, magnesium will be placed in the round bottom flask and then halides are slowly added. Another potential source of error is that Grignard reagents must…
A important tests were performed on the product to pressure the results: melting point value, percent yield, IR, and TLC. The experimental melting point value was found to be a range of 165-167 ºC being a little lower than the literature value for camphor, the intended product, was 175 ºC. The sharp range was resulted in a slightly pure product. The percent yield was lower than expected which can be the reason most of the product was lost during the extraction and almost completely sublimated…
Ethyl vinyl ether was used to protect –OH on glycidol based on a literature reported protocal.59 In a typical procedure, 0.675 mol glycidol and 200 mL ethyl vinyl ether were loaded in a round-bottom flask, to which 1.25 g TsOH was then added. The reaction was allowed to proceed at room temperature (RT) for 3h. The resulting mixture was then purified by washing with 100 ml saturated aqueous solution of NaHCO3 for 3 times. The organic layer obtained was dried by MgSO4. After filtration of MgSO4,…