Aspirin

investigate whether different formulations of aspirin would affect its bioavailability. This required the use of normal aspirin tablets, aspirin tablets with sodium bicarbonate, soluble aspirin, and enteric coated aspirin. Depending on which group the students were allocated they administered different formulations of aspirin. The pH and the concentration of salicylate in each urine sample, collected at different time points, was determined after administering the drug. A standard curve for salicylate was generated to calculate its concentration in each urine sample by comparing the optical density using the following equation: change in optical density (from control)×1/(gradient of graph)=concentration…

Here is an interesting fact about aspirin: one hundred billion aspirin tablets are consumed yearly on Earth. That is four hundred thousand tons of aspirin (Dodziuk, 2013). Aspirin is a very common household drug and it is very widely used in the medical industry today. Most people know this drug as a pain reliever. However, it can do many other things than just that. Aspirin is not a drug that produces anesthesia or causes someone to lose consciousness. Aspirin is also used to reduce fevers,…

Medicine has evolved greatly, especially in terms of drugs, but one of the basics is aspirin, also referred to as acetylsalicylic acid. There are many different reactions that can be conducted in order to synthesize aspirin. One way being the Fischer esterification, which is a reaction between an alcohol and a carboxylic acid within the presence of a catalyst, synthesizing an ester (Weldegirma, 2014). The catalyst has to be something that will provide the addition of a proton, such as a Lewis…

Aspirin Effects on Sunflower Germination TESTABLE QUESTION: What are the effects of different amounts of aspirin on sunflower germination? BACKGROUND: Aspirin is probably the most well-known pain killer. Aspirin is a salicylate, a bitter compound present in certain plants, and a nonsteroidal anti-inflammatory drug. Aspirin can treat headaches, pain, fever, and inflammation. It can also decrease the risk of a heart attack, strokes, and chest pain. It works by blocking a certain natural…

Abstract: The objective of this experiment was to synthesize aspirin from salicylic acid and acetic anhydride. The general theory behind this experiment was to study the synthesis of a drug from organic materials. During the experiment, esterification had occurred between reactants salicylic acid and acetic anhydride. Then, phosphoric acid would catalyze the reaction and water would be added to decompose the remaining acetic anhydride. Through the process of filtration, aspirin crystals were…

Research Article Pharmacy Practice GELLIFIED EMULSION FOR SUSTAIN DELIVERY OF ASPIRIN AS ANTI-INFLAMMATORY INTRODUCTION Aspirin is a non-steroidal anti-inflammation drug (NSAID). It widely use as analgesic in treating mild to moderate pain such as injury, headache, arthritis, menstrual cramp and other musculoskeletal condition. Aspirin is an ester of salicylic acid, while after ingestion it will undergoes hydrolysis which produce salicylic acid and acetic acid. Salicylic acid…

In this lab we used one of the most common synthetic medicine, Aspirin. Aspirin is the common name but it can also be known as Acetyl Salicylic Acid. Aspirin came to be because the hard work of scientist who were trying to relieve pain and fight fever without the patient suffering deadly side effects. A breakthrough occurred when a chemist named Felix Hoffman knew that phenolic compounds are corrosive because of the free hydroxyl group located on the benzene ring of salicylic acid. He then…

Task 3 P1 When using thin layer chromatography (TLC) to test for purity of aspirin it is a quick and simple method. Firstly when using the TLC method you need to have a TLC sheet and mark on the sheet 0.5cm up on the sheet and draw a line, make sure you don’t press too hard on the paper as this will disrupt the absorbent on the paper. You need to make sure the samples have been marked on the paper so you don’t get mixed up and leave a gap between the aspirin samples so they don’t run together…

Aspirin is produced from the reaction of Salicylic Acid and Acetic Anhydride. Aspririn is a analgesic and antipyretic. The purpose of this experiment is to produce aspirin and analyzing it for yield. Twenty grams of salicylic acid, molecular weight 138.1g/mol, 5.0 mL of acetic anhydride, molecular weight 102.1g/mol and density 1.08g/mL, and 5 drops of concentrated sulfuric acid were mixed in a 125mL flask. The mixture was heated in a 70°C hot water bath then taken out to cool to room…

General Facts: • Aspirin is an acetyl derivative of salicylic acid. It works by reducing substances in the body that cause pain. • Its scientific name for Aspirin is Acetylsalicylic Acid. • Another common name for Aspirin is ASA. • Its chemical formula is C9H8O4 . • It has a melting point of 136 degrees Celsius and a boiling point of 140 degrees Celsius. • It's odorless, colorless and can be white powder. Historic background: • The origin of aspirin has evolved for the past centuries going…