Aspirin

1950 Hoffman- La Roche Swiss healthcare and pharmaceutical company in Europe was the first developed Benzodiazepines founded by scientist Leo Sternbach. Between 1960 and 1970 Sternbach and a group of researchers under his direction helped him altered the primary benzodiazepine complex and introduced many different benzodiazepine which include flunitrazepam. With the development of flunitrazepam Leo made Roche pharmaceutical industry a very big hit. By 1975 Roche released many of Sterbach’s…

The anti-benzoylecgonine (cocaine) monoclonal antibody [IP3G2] (mouse IgG1, catalog no. GTX44358, lot 821400072, 3.75 mg/ml) was purchased from Gene Tex (Irvine, CA, USA). The second anti-benzoylecgonine monoclonal antibody [IP3G2] (mouse IgG1,catalog no. MAB4029, lot 8H23323, 3.75 mg/ml) was purchased from Acris Antibodies (Herford, Germany). The secondary antibody, a polyclonal anti-mouse IgG from sheep (catalog no. R1256P, lot 21481, 2.2 mg/ml), was obtained from Acris Antibodies (Herford,…

EXPERIMENTAL RESULTS The present study was undertaken to formulate Solifenacin succinate immediate release tablets. The study involves preformulation studies of drug excipients, formulation and processing development along with evaluation of tablets made with the optimized formulation. Finally tablets were evaluated by in-vitro methods. 6.1. Drug excipient compatibility study Table 1. Results of compatibility study S.No. Name of Excipient Ratio of API/ Excipient Initial…

Hydrocodone is a popular drug used to relieve pain or to suppress coughing. This drug is a close relative to Codeine, which is also a painkiller. Hydrocodone has been around for about 95 yeas and it has made its way to the second most abused drug in the United States. So how did this drug make its way from a medical breakthrough to a highly abused substance? Hydrocodone was first created by a German pharmaceutical company known as Knoll. It was created in the 1920’s by simply attaching a…

Pharmacodynamics: Ibuprofen is a NSAID with anti-inflammatory; analgesic and antipyretics effects are the results of the ability to block the cyclooxygenase (COX) enzyme system, leading to the inhibition of the synthesis of prostaglandins [6]. COX is the enzyme used for prostaglandin biosynthesis [3]. Both COX-1 and COX-2 enzymes are involved with prostaglandin production. The inhibition of these enzymes results in decreased synthesis of prostaglandin thus decreasing pain, fever, and swelling…

As we get older people become responsible, as adults we are responsible for several things. Through time we probably have many responsibilities that we stress over and we might develop major health issues. Two of the most common chronic headaches in the world are tension and migraine headaches. These headaches are mostly common in adults could start at any age but it 's mostly common in the ages of 20’s-40’s. In the US 12% percent of Americans suffer from headaches like tension and migraine…

Analysis of aspirin tablets Purpose: Determine the percentage of 2-ethanoylhydroxybenzoic acid in aspirin tablets. Introduction (including background information) : Before creating Aspirin, “sail alba” was used. In 1860’s, chemists discovered that Salicylic acid (2-hydroxybenzoic acid, C7H6O3 ) is the active acid in sail alba. Salicylic acid is relatively strong though. It can irritate and damage the stomach membranes and mouth. In 1889, ethanoate ester of salicylic acid was introduced by the…

synthesising aspirin and reinforce both the skills of recrystallisation and melting point determination. In this experiment, we are supposed to measure the amount of aspirin collected to calculate the percentage yield of aspirin. Apart from that, we are also required to find the melting point of aspirin. Introduction: 1.1: aspirin Aspirin, also known as acetylsalicylic acid, is an aromatic compound containing both a carboxylic acid functional group and an ester functional group. Aspirin,…

and chemical properties. Materials & Apparatus: -eye protection -well plate -pipette -small toothpick/ paper clip for stirring -6 white powders: icing sugar, cornstarch, Aspirin powder, baking powder, mystery powder -test solutions in dropper bottles: water, universal indicator, vinegar, iodine solution Safety notes: Aspirin Powder- in case of contact with skin, wash with soap and water. Universal indicator- toxic, in case of contact with skin or eyes, rinse for 15 minutes. Iodine- rinse for…

In Dr. Perz’s lecture she gave us an example of how taking aspirin for a headache does not mean that a headache is caused by an aspirin deficiency. I believe this to be an excellent example of what Dr. Szasz and Dr. Frances are trying to communicate. Both Dr.’s Szasz and Frances voice concerns about our society blaming our biology for what could simply be a result of free will. A person choosing not to utilize self-control doesn’t mean that person is mentally unstable. Children who are out of…