Aspirin

around the wound, and this leads to pain and inflammation. During bacterial infections, however, they are produced by the hypothalamus, resulting in an increase in body temperature. The therapeutic effect of aspirin stems from suppressing the secretion of prostaglandins. As observed, aspirin inhibits the secretion of prostaglandins by inhibiting the enzyme that facilitates the biochemical reactions responsible for the production of prostaglandins. The reason the enzyme (which is a catalyst) is…

Still, Aspirin and its derivatives enjoyed widespread success until the advent of acetaminophen and Ibuprofen as cheaper Aspirin alternatives in the mid 20th century. Aspirin 's popularity was dealt another severe blow in the 1980’s, after a study was published which suggested a connection between aspirin consumption in children and the development of Reye syndrome, a disease which causes death in 20-40%…

experiment was to perform a synthesis of aspirin/ acetylsalicylic acid from salicylic acid, using a chemical synthesis procedure. The synthesis involved breaking the bond with acetic anhydride, also required heat and a catalyst, phosphoric acid, in order to beak and extract the bond. The solution used water in order to purify the solution in the way of recrystallization. The product was characterized using IR spectroscopy and melting point. The pure aspirin product that was formed in this…

The components of Alka Seltzer come together to form a pain reliever and antacid formulation. Aspirin is classified as a Nonsteroidal Anti-inflammatory Drug and has the function of a pain-killer, helping to reduce inflammation, fever and pain within the body by reducing the production of a substance called prostaglandins which are “hormone-like substances” (Drugs 2017) that regulate the inflammation and cause the bodies pains and headaches.(Merck Animal Health) The Sodium Hydrogen Carbonate…

Introduction: According to Drugs.com, “Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID). It works by reducing hormones that cause inflammation and pain in the body.” This includes conditions such as headaches, painful menstrual periods, toothaches, back pain, dental pain, migraines, arthritis and any minor injuries. Ibuprofen is also used to treat and reduce fever as well and is typically administered to individuals, both adults and children ages 6 months and older. Ibuprofen has been…

• Analgesics – i.e. Co-codamol, Codeine, or Paracetamol to treat and prevent pain. Codeine, used for pain relief, (i.e., head-aches) common side effects can be; light-headedness, dizziness, nausea, vomiting, shortness of breath, and sedation. Codeine can also cause allergic reactions, symptoms of which include constipation, abdominal pain, rash and itching. Addiction to these, Irritation of the stomach, liver damage and sleep disturbances as some analgesics contain caffeine, if taken over a…

There are a few different types of pain medication. Non-Narcotic Analgesics are commonly used to treat mild to moderate pain and reduce fever. Nonsteroidal anti–inflammatory drugs (NSAIDs) are used to reduce pain and inflammation. Narcotic pain medications are used to treat severe pain. COX-2 (Cyclo-oxygenase-2) inhibitors are a unique type of nonsteroidal anti-inflammatory drug designed to relieve pain without upsetting the stomach. I am going to address acetaminophen. It is a Non-Narcotic…

Chapter 1: Introduction 1.1 Nature of the Dissertation Identification, quantification and analysis Amoxicillin and Flucloxacillin Sugar free antibiotics which are manufactured at Athlone Laboratories by high liquid fluid chromatography (HPLC). The project also involves Method Transfer validation by analysis Amoxicillin Sugar Free for the new project of GSK Mayenne France, this involved Identification, quantification and analysis of carrying Amoxicillin Trihydrate API and Sodium Benzoate in…

Bayer is known for making a large amount of pharmaceutical drugs. They make OTC drugs, animal health care, plastics, and high-performance materials, crop protection, and home garden care (Bayer: Science For A Better Life, 2011). The corporation is known for making brands like Aleve, Alka-Seltzer, and One-A-Day vitamins and the company is a top seller in multiple sclerosis treatment Betaseron and birth control pill called Yasmin (Mackenzie, 2011). Aleve is a product that can aid in any medical…

The aim of the present investigation is to intend, develop and evaluate a pulsatile drug delivery containing a core-in-cup based system of dry coated tablet of ketoprofen based on chronomodulated approach for management of Rheumatoid Arthritis. This pulsatile system contained a core tablet surrounded by an impermeable outer shell and top cover layer. Core tablet contained the active ingredient acting as reservoir, ethylcellulose was used to form an impermeable outer shell, the top cover layer…