Salicylic acid

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  • Willows Research Paper

    the results of his study to the Royal Society, who then published it. The medicinal characteristics of willow bark are a result of salicylic acid, or salicin, a compound which is contained in the tree’s sap and can also be found in plants such as myrtle. The first rigorous clinical trial regarding salicin was conducted in 1874 by the Scottish physician Thomas MacLagan, whose results confirmed those of Stone’s study. Salicin was first isolated from willows years prior to McLagan 's study in 1829, by Henri Leroux, a French scientist. Once an inexpensive method for synthetically producing the compound was perfected in 1857 by the German chemists, Kolbe and Lautemann, salicin enjoyed a degree of success as a anti-inflammatory medicine. It’s comparative cheapness also contributed to its popularity, as its primary rival, quinine, had to be obtained from cinchona tree bark which was in far less readily available than willow bark and far more expensive than the synthetically derived salicin. A 19th century edition of the British Medical Journal notes that: The value of quinine has probably been enhanced by the prospect of an outbreak of war in the east of Europe. Salicine has suddenly sprung into favour as a drug, and is made only from the willow bark, and that only at stated times of year. Salicylic acid and its compounds, being made from carbolic acid, have not increased in price by the late augmented demand for their use in medicine which has occurred. Unfortunately, its…

    Words: 1586 - Pages: 7
  • Research Paper On Aspirin

    disease that can develop after strep throat (Marks, 2015). Nordqvist’s article stated, “Taking aspirin in your 40s could cut the risk of cancer developing later in life.” In addition, another source stated that people would have to take the drug for at least five years for there to be any results (Boseley, 2014). Aspirin has also been known to be used to treat Kawasaki disease. This is a disease that can cause heart problems in children (Marks, 2015). Many people may already be aware of these…

    Words: 1842 - Pages: 8
  • Why Avoid Warts

    easily right at home. Read on to find out more about the home treatment methods for removing warts. Some easily available wart removing medicines: Since these are a common problem in children, they need quick and careful treatment. Thus there are quite a few products for easy wart removal, on hand. However, the effects of these products are very unpredictable. Some products can work very efficiently to remove this disease in children, whereas some other products have no effect on the condition.…

    Words: 1564 - Pages: 7
  • Aspirin Essay

    A high salicylate concentration indicates that more acetylsalicylic acid, aspirin, is absorbed. This is because the metabolism of acetylsalicylic acid leads to the production of salicylic acid and salicyluric acid by hydrolysis and conjugation of glycine respectively. Hence, in a urine sample the detected concentration of salicylate reflects the amount of salicylic acid and salicyluric acid excreted, which provides a method for measuring the amount of acetylsalicylic acid…

    Words: 963 - Pages: 4
  • The Synthesis Of Aspirin

    Medicine has evolved greatly, especially in terms of drugs, but one of the basics is aspirin, also referred to as acetylsalicylic acid. There are many different reactions that can be conducted in order to synthesize aspirin. One way being the Fischer esterification, which is a reaction between an alcohol and a carboxylic acid within the presence of a catalyst, synthesizing an ester (Weldegirma, 2014). The catalyst has to be something that will provide the addition of a proton, such as a Lewis…

    Words: 746 - Pages: 3
  • Willow Tree Lab Report

    attempted to covert salicylic acid into a form that would provide the same medical benefits without the side effects. In 1852, Charles Gerhart was the first to attempt to acetylate the hydroxyl group thus creating acetylsalicylic acid. However the acetylsalicylic acid product…

    Words: 1309 - Pages: 5
  • Ferric Chloride Test Lab Report

    Introduction The ferric chloride test is used to determine the presence of phenols in a given sample or compound (for instance natural phenols in a plant extract). Enols, hydroxamic acids, oximes, and sulfinic acids give positive results as well. The ferric chloride test can be used to detect metabolites in urine in case of inborn error of metabolism such as phenylketonuria. In addition,the Ferric Chloride test can be used to detect salicylates in urine after an aspirin overdose.1 Background…

    Words: 1105 - Pages: 5
  • Difference Between Solubility Dependent Extraction And Recrystallization

    The process of extraction also heavily weighs on the fact that compounds are more favorably soluble in a certain solvent based on solubility characteristics of the desired compound. There are four factors that determine the solubility characteristic of a compound: pH, temperature of the solvent, pressure of the system, and ionic character of solute. Ionic character and pH were manipulated to increase solubility favorability of the compound in extraction solvent. In essence, pH is the easiest…

    Words: 1249 - Pages: 5
  • Synthesis Of Aspirin Essay

    Aims: The objectives of this experiment are to carry out the process of synthesising aspirin and reinforce both the skills of recrystallisation and melting point determination. In this experiment, we are supposed to measure the amount of aspirin collected to calculate the percentage yield of aspirin. Apart from that, we are also required to find the melting point of aspirin. Introduction: 1.1: aspirin Aspirin, also known as acetylsalicylic acid, is an aromatic compound containing both a…

    Words: 1003 - Pages: 5
  • Aspirin Lab Report

    Analysis of aspirin tablets Purpose: Determine the percentage of 2-ethanoylhydroxybenzoic acid in aspirin tablets. Introduction (including background information) : Before creating Aspirin, “sail alba” was used. In 1860’s, chemists discovered that Salicylic acid (2-hydroxybenzoic acid, C7H6O3 ) is the active acid in sail alba. Salicylic acid is relatively strong though. It can irritate and damage the stomach membranes and mouth. In 1889, ethanoate ester of salicylic acid was introduced by the…

    Words: 1110 - Pages: 5
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