Laboratory rat

consuming a high salt diet and how it impacted the central nervous system — “HSD2 and NPFF Immuno reactive Expression in Response to Sodium Diet.” Sprague Dawley rats were used as the representative mammal model and were used to analyze the change in activation of two central nervous system neurons. During this program I learned to meticulously analyze neuronal expression through RTPCR testing from prepared isolated RNA samples, immunohistochemistry staining procedures and mounting medulla tissue. Furthermore, the NIH summer research program allowed me to clearly understand the basic mechanisms of the cardiovascular system in response to a poor diet and also how to productively conduct various molecular tests when analyzing genetic material. In addition, I recently completed a research training program (Leadership Alliance) hosted at Brown University. My research was conducted in Vascular Research lab located in the VA Medical Center. My project identified the health effects of cigarette smoke (CS) and acrolein (CS induced aldehyde) on lung permeability via protein modification. We hypothesized the CS and Acrolein exposure would increase protein carbonylation in proteins that are responsible for keeping an adherent endothelial monolayer.C57BL/6 mice model were used for general lung homogenate analysis and we used rat lung microvascular endothelial cell (RLMVEC) as the cell line. The research training that I received from both NIH funded programs further confirmed my…

alkyl, allyl, and benzyl halides on 17b-hydroxy-3-methoxy-11-oxo-estra-1,3,5(10),8(9)-tetraene (10). The novel compounds (10 and 12–17) were appraised for their preliminary post-coital contraceptive (anti-implantation) activity in Sprague–Dawley rats. The tested compounds were managed orally and exhibited noteworthy anti-implantation activity. Compound 13 is the furthermost strong compound in the sequence which exhibited 100% contraceptive efficacy at 1.25 mg/kg. 6. Emerson Luiz Botelho Lourenco…

testing on sleep/wake rats that measures in a streptozotocin-induced rat model of Sporadic Alzheimer’s disease. I will be focusing on object recognition testing in mice where they have the ability to perceive certain objects by its physical features such as color, shape, size, texture to determine how your short-term memory works when one or two different objects are placed for a certain period of time. The term “object recognition” means exactly as it states, it is how the memory reacts to…

IN, USA). The animal procedures are approved by the Animal Care and Use Committee of East Tennessee State University, as well as complied with the NIH Guide for the Care and Use of Laboratory Animals. These animals were housed on a 12:12 h light cycle (lights on at 07:00 a.m.). Water and food were provided ad libitum. Rats were randomly assigned to different experimental groups after living an acclimation period of 5 days. The CSD paradigm is the same as reported previously (Chen et al.…

However other scientists were skeptical towards to the experience, since in the past research such effect was not demonstrated. The author also mentions how some scientist criticized that perhaps it was not the enriched environment that produced that brain change, but rather the how the rate was handling or stress. In addition, argument was made that the impoverished rat was stressed, and that’s what made that change in the development of the brain. In the further addition, the authors mention…

Remy despite being a rat embodies superior qualities, he is clean, refuses to walk on all fours to avoid soiling food with dirty front paws. Remy’s rat colony comes across as a belonging to a working-class status. Rats live in close quarters near humans but in abject condition under roof and sewers. Rats are dirty and uncouth. They feed on garbage and leftovers and stolen food. They had to be steamed clean and purified before entering the restaurant to prepare food. The subtext embedded…

An example of a medication that did not succeed through testing would be penicillin. This medication was first tested on a lab rat and the scientist was very disappointed about how his discovery did not work. However, when he had a patient and no other medication to give them the scientist gave the patient penicillin. It was soon discovered that this was a life saver and although it did not work on a rat, it worked on a human. Not only that, but in a recent study it was discovered that using…

With lambs, not one mistake was made while they were on the visual cliff. The baby goat, it became frightened and froze showing that the goat was in complete control of his/her visual sense. Kittens too were found to have great sense of perception as soon as they were able to move on their own at about 4 weeks old. However, for the rats it was a different story. They did not appear to show any preference towards the shallow side of the table, but this may be because rats use the sense of smell…

used in medicine. In humans it is known to stimulate contractions in labor, increase milk ejection in lactation (4,5), and is found at increased levels during pleasurable activities such as a massage or sex (3). It is known by many names, the trust hormone, the love hormone, the cuddle hormone, because of the wide variety of behaviors it is known to affect. More recently, oxytocin is being researched for its role in social behaviors. It is believed that it may have a role in both romantic and…

Cows are one of the closest relative to humans. With a 99.3% DNA match, whatever that happened within a cow's system should also be happening within a human. The natural lifespan of a fully grown cow is 15 years. The energy production of a cow was just as efficient and strong as a humans. The rat is another close relative to humans. The cells within the rat also were decaying at normal rates. However, the numbers that were returned for the human cells did not add up. S**t. Sylas looked over…