PURPOSE
The purpose of this study is to measure object recognition testing on sleep/wake rats that measures in a streptozotocin-induced rat model of Sporadic Alzheimer’s disease. I will be focusing on object recognition testing in mice where they have the ability to perceive certain objects by its physical features such as color, shape, size, texture to determine how your short-term memory works when one or two different objects are placed for a certain period of time. The term “object recognition” means exactly as it states, it is how the memory reacts to recognizing something they have seen before. For example, the study is conducted where the first session you are given two identical objects and then the second session you replaced one of …show more content…
Fortunately, the laboratory is mostly wet lab so I will be able to gain first hand experience such as weighing the rats, injections of streptozotocin (ICV-STZ), many experimental procedures and sacrificing the rats as well. I want to fully understand what object recognition test does to the rats when they test their behavioral patterns. I am hoping to collect as many data as I can to analysis which learning trials work better for the rats and how it tests their cognitive behaviors. I would like to know about other tests such as novel, unique and social discrimination tests to compare it to object recognition test because I want to know why this method is considered the best testing experiment for this research …show more content…
This research project focuses on Alzheimer’s disease and the study of rats for approximately 108 days to observed how these rats behave when they are injected with streptozotocin (ICV-STZ); it is a chemical that is particularly toxic to the insulin producing beta cells of the pancreas in rats in type 1 diabetes. Classes such as Bioinformatics I, II and Computational Genomics has help me to broaden my knowledge because it forms a connection of how diseases came about and possible cures we can find for any particular disease. For example, my final presentation was based on the Neanderthals and how we inherited genes from them and how we share similar physical
The purpose of this study is to measure object recognition testing on sleep/wake rats that measures in a streptozotocin-induced rat model of Sporadic Alzheimer’s disease. I will be focusing on object recognition testing in mice where they have the ability to perceive certain objects by its physical features such as color, shape, size, texture to determine how your short-term memory works when one or two different objects are placed for a certain period of time. The term “object recognition” means exactly as it states, it is how the memory reacts to recognizing something they have seen before. For example, the study is conducted where the first session you are given two identical objects and then the second session you replaced one of …show more content…
Fortunately, the laboratory is mostly wet lab so I will be able to gain first hand experience such as weighing the rats, injections of streptozotocin (ICV-STZ), many experimental procedures and sacrificing the rats as well. I want to fully understand what object recognition test does to the rats when they test their behavioral patterns. I am hoping to collect as many data as I can to analysis which learning trials work better for the rats and how it tests their cognitive behaviors. I would like to know about other tests such as novel, unique and social discrimination tests to compare it to object recognition test because I want to know why this method is considered the best testing experiment for this research …show more content…
This research project focuses on Alzheimer’s disease and the study of rats for approximately 108 days to observed how these rats behave when they are injected with streptozotocin (ICV-STZ); it is a chemical that is particularly toxic to the insulin producing beta cells of the pancreas in rats in type 1 diabetes. Classes such as Bioinformatics I, II and Computational Genomics has help me to broaden my knowledge because it forms a connection of how diseases came about and possible cures we can find for any particular disease. For example, my final presentation was based on the Neanderthals and how we inherited genes from them and how we share similar physical