Hyperthermia

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    Silent, but Deadly 2 Abstract Malignant hyperthermia is a very rapid onset crisis that happens during a surgical procedure. It is unnoticeable and is an adverse reaction to anesthesia that was given in either form of volatile agents or succinylcholine. It is undetected in most cases unless having been tested for this particular type of reaction either through muscle biopsy or genetic testing. The reason for the absence of detection in most cases, is that the only way to trigger malignant hyperthermia is inducing in the patient via the triggering anesthetics. Treatment for malignant…

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    However, many athletes practice in hot and humid weather conditions which intensify the test that physical exercise places on the thermoregulatory processes. The hot and humid setting weakens the heat exchanges between the body and the environment considerably. The struggle between the body and environment can lead to serious heat illnesses in athletes, such as, heat stroke, dehydration and heat exhaustion (Wendt, 2007). When an individual exercises, their core body temperature increases from…

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    The article that I choose was called “Targeted Temperature Management at 33°C versus 36°C after Cardiac Arrest”. The objective of the article was to find at which temperature was it better to induce hypothermia on a patient who had gone into cardiac arrest in an out-of-hospital scenario to prevent neurological damage and the. The researchers hoped that if by inducing hypothermia early on after the cardiac arrest and loss of consciousness there would be little to no brain damage. The researchers…

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    Thermal Comfort Essay

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    There are many definitions of thermal comfort, which depends on the aims and expectations of those who defined it (Chappells, and Shove, 2004). Jiao (2010) stated that, the rate at which human body gain and lose energy, and also the state of comfort is satisfactory once all heat flow in and out of the body are in equilibrium. Also, (ASHRAE 2004), described it as “the state of mind that expresses satisfaction with the surrounding environment.” This definition highlights subjective and…

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    At Home Care and Avoiding Heat Stroke Heatstroke is the most serious of the heat-related conditions typically known as heat cramps, heat exhaustion, and heat stroke. Heatstroke is a critical condition requiring immediate medical attention. According to WebMD, if it is not treated in time, it can damage the brain, heart, kidneys' and muscles. In a short time, heat stroke will lead to death. Heat stroke is contrasted from the serious but not usually fatal heat exhaustion in a couple of ways.…

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    This condition was in one of the clinical correlations which I thought was interesting how the body’s energy processes worked against themselves. Malignant hyperthermia (MH) is a rare, inherited life-threatening condition that is induced by general anesthetic drugs such as halothane. Generally, most cases show no signs or symptoms until individuals are exposed to anesthesia. However, there are cases where an individual with MH goes under anesthetics and will not react. The reaction includes a…

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    Decades ago 2,4-Dinitrophenol (DNP) was introduced as a weight loss drug acting as an agent that uncouples oxidative phosphorylation causing significant increase in basal metabolic rate. However, the consumption of the product has resulted in many deaths due to misuse causing adverse effects such as hyperthermia, tachycardia, diaphoresis and tachypnea. The rate of metabolism is closely linked to the rate of respiration; therefore, if metabolism is increasing there should also be an increase in…

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    In Luis Alberto Urrea’s novel, “The Devil’s highway,” he uses a passage that describes the migrants’ digression towards death as they travel across the Yuma desert to create an uncomfortable, and sympathetic feeling from the audience. Throughout the book, Urrea uses imagery to describe the harsh conditions of the desert, and the high risk that comes along with attempting to cross it. The passage goes into detail about the unavoidable stages of hyperthermia and how each of these effects the body.…

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    mitochondria (Grundlingh et al. 2011). DNP can alter the process of oxidative phosphorylation, and this can lead to weight loss. In order to produce ATP, the body uses carbohydrates and lipids. DNP can mess this up by interfering with ATP as it is being produced. Protons are transferred across the membrane, and this is what disturbs the process of ATP. Since the body needs fats and carbohydrates in order to make energy, and they do not have that in this situation, the metabolic rate of the body…

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    destruction (Dougherty, Gomer et al. 1998, Brown, Brown et al. 2004). Different from photodynamic therapy, PAT therapy is based on conversion of absorbed energy in thermal (hyperthermia) to damage the tumor tissue while leave the neighboring cells intact (Kelkar and Reineke 2011). To help overcoming the limitation of the conventional treatment, thermal ablation therapy, which can ablate cancer cells at high temperatures (>45°C), may be able to offer a simple and invasive alternative therapy…

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