Genomics

To do this, the samples will need to be grinded down, which allows for the cells to break apart and release the cell’s contents. In doing this, the cell’s genomic DNA is now released from the cell. The genomic DNA is the complete set of genetic information for that organism. This is used for the reaction with the PCR to create the copies needed. While grinding the sample, DNAase-free water will be used to aid with the break down…

they are broadly grouped under the category of carcinoma, sarcoma, lymphoma or leukemia based on the type of tissue origin. common striking features of all types of cancer is uncontrolled cell proliferation, antiapoptosis, enhanced angiogenesis, genomic instability and metastasis. 4 The broad range of devastating characteristics of the cancer makes it a very good therapeutic target for designing the small molecules. In cancer drug discovery programme, researchers have contributed many novel…

1) Alcaligenes faecalis is a Gram-negative coccobacilli that is motile, oxidase positive, catalase positive, non-spore-forming, non-fermenting, slow growing, and citrate positive obligate aerobe (Mahon et al., 2014) (Sachdeva et al., 1963). Its colony morphology is flat, thin, and rough with irregular edging (Mahon et al., 2014) and the flagella varies between the usual shape versus the curly structure, however, both shapes do not exist on the same individual bacteria (Leifson, 1960). The…

I would like to present the book chapter (leading and corresponding author) and one of my research articles (co-first author) and the as academic writing samples here. The book chapter entitled “Genomics and Proteomics in Brain Complexity in Relation to Chemically Induced PTSD” was published in Handbook of Toxicology of Chemical Warfare Agents, Second Edition edited by Dr. Ramesh C. Gupta and the research article “Regulation of the Apolipoprotein…

In the article “ A study of lived experiences of registered nurses who have provided end-of-life care within an intensive care unit”, by Holms in 2014, the author discussed the qualitative research that was done to determine what registered nurse’s knew about life of end care and and how they felt about end of life care in the intensive care unit. In this study the phenomenological qualitative research design was used and took place in an ICU in Scotland. “Phenomenological studies describe the…

It’s important to realize that each scientific break through is made possible by the work that came before it. It’s a lot like putting puzzle pieces together, collecting different important evidence until enough puzzle pieces result in another break through. Fifty years ago two scientists announced to a lunch time crowd that they had discovered the secret to life. How DNA changed the world To begin with scientists used to have no understanding of what caused distinct patterns of inheritance.…

Ever since scientists uncovered more information about genes, DNA, etc., a lot of scientific advancements linking to the topic have risen like, DNA fingerprinting, gene therapy, and manipulating genes. Lily E. Kay’s Who Wrote the Book of Life: A History of the Genetic Code published in the year 2000, talked about the detailed history of one of the most important events in modern science, the genetic code. Genetic code is the sequence of organic bases on the double strands of DNA. The bases are…

We are now beginning to understand the negative effects of chronic sleep deprivation, and how it impacts our ability to function as well as our physical and mental health. However, we still need to better understand the functions of sleep to develop new treatments for the countless disorders that affect one’s ability to maintain sleep homeostasis. The answer to this is to conduct further scientific research. Millions of people go through life with undiagnosed chronic sleep disorders. The word…

decided to explore the consequences of genomic research through its Ethical, Legal, and Social Implications (ELSI) program. The HGP began in 1987 with the motive of needing to know what drives all basic science. There was much competition between the private sector and the public sector, with J. Craig Venter leading the private sector effort. By 1998 Venter had established Celera Genomics, with sequencing capacity fifty times greater than The Institute for Genomic Research. By June 17, 2000, he…

have an influence on chromatin features. These features include things such as nucleosome position, binding factors, and histone modifications. Active chromatin are more accessible compared to other chromatin and show more decay as a function of genomic distance. They are also organized into linear domains and are shorter than other chromatin types. They can be organized into TADs which suggests that they are spatially independent. Internal interaction is different between cells of a different…