Freedom of expression

The Basics of Gene Expression and Control Genetics is a very diverse field of science, because it encompasses so many aspects of not only what happens inside organisms, but also how offspring relate to parents and ancestors and many other processes. Although every bit of genetics is important, many things in an organism would not be possible without the expression of genes. Through expressions of genes, organisms provide for themselves and "fulfill" what is the basis of their genetic…

Hypothesis: 1.) Animals with nocturnal sleep cycles will have greater similarity in the PER gene than the PER gene of diurnal animals. 2.) Differences in the sequences of PER genes can account for variance in the free running period (FRP) between varying organisms. 3.) Human PER gene homologs arose from prior duplication events throughout evolution. Motivation and Background: The biological clock is an endogenous mechanism that regulates the physiological activities of an organism. It was…

Mutations in genes can have complicated relationships and interactions that affect the phenotype of an organism. Possible genetic variations include nonsynonymous mutations, deletion of coding sequences, translocations, transposable element insertions, alterations within introns and disruption of regulatory elements, as examples. These alterations can cause a range of phenotypic effects from no effect to cell death for essential genes. Disruptions that result in an essential phenotype are…

Downstream Targets Due to the lack of developing an effective Ras treatment, some have turned to targeting downstream effectors of Ras. Downstream effectors have a critical role in Ras carcinogenesis and are commonly found in KRAS mutated cancers. The most intensely targeted pathways are the Raf-MEK-ERK (MAPK) and PI3K-AKT-mTOR signaling pathways. Raf-MEK-ERK MAPK signaling is initiated through receptor tyrosine kinases after their activation by growth factors (Mccubrey 2006). Once Ras is in its…

Research into the genetics of deafness has shown that mutations in the CX26 gene, located on human chromosome 13q11, cause non-syndromic recessive deafness (9, 10). Expression of GJB2 has been documented in a variety of cells and tissues. In the cochlea, CX26-containing gap junctions are proposed to maintain K homeostasis by ferrying K away from the hair cells during auditory transduction(11). Recently, it has been shown…

scientifically prove if a suspect of committing a crime is truly the person who committed the crime. The four main components of a PCR are: DNA from a sample, nucleotides A, T, G, C, DNA polymerase, and primers. B. What is gene expression? List the two steps of gene expression and where they occur in the cell. (2 points) Genes are genetic codes or also known as sections of DNA. In order for this genes to be useful to a living organism, they need to be turned into useful products. The process…

Question 1: a) A: Promoter B: Splice site C: 5’ UTR D: Start codon E: Stop codon F: 3’ UTR b) The sum of the exons and introns (all in kilobases) (1.2+8+0.7+27+0.4+11+3.1) = 51.4 kb. c) The sum of the exons (all in kilobases) (1.2+0.7+0.4+3.1) = 5.4 kb. d) RNA Protein Truncation mutation in exon 2 Same length, same amount of RNA produced. Shorter in length (due to earlier stop codon), same amount of protein produced, usually changes the protein to non-functional, though not always. 3bp in…

DNA makes proteins. DNA is stored in the nucleus and contains phosphates (a phosphate includes nitrogen bases). DNA is made up of these phosphates, but, in making polypeptides, or a protein, the nitrogen bases are the most important in his process. To make a polypeptide, the helicase unzips the double helix figure, making two rows, or strands, which are one side of all of the nitrogen bases. Floating nitrogen bases string the opposite of these sides, to make an original copy, but leave, ending…

transcribed. The deletion of the paternal allele, which occurs in 70% of cases (this occurs when a segment of the paternal chromosome 15 is deleted in each cell), or maternal uniparental disomy (UPD), which occurs in 25% of cases, leads to loss of expression of SNRPN gene, and thus, to Prader-Willi syndrome. UPD causes the affected individual to have two copies of chromosome 15 inherited from their mother instead of one copy from each parent. Prader-Willi syndrome can also be caused by a…

individuals or groups and makes the building blocks of society. In human interaction, there is a constant exchange of nonverbal and verbal communication. Nonverbal communication involves communication without a spoken language and includes facial expressions, eye contact, gestures, spatial differences,body position and posture known as body language. Nonverbal communication is informative when observing and analyzing interactions and how individuals react to each other. Additionally, the…