Amino acid

An insight in the biophysical properties of bio macromolecules Natural biopolymers such as nucleic acids, proteins and carbohydrates are essential for life as we see it today. It is incredible to think how this vast set of molecules that are in every living thing, from bacteria to human beings, are mostly made up by six elements (carbon, hydrogen, oxygen, nitrogen, sulfur and phosphorus). These biopolymers have the properties to, from small monomers, build giant tridimensional structures with a…

Introduction Osteogenesis imperfecta describes a group of genetic disorders that are colloquially known as “brittle bone disease” and is estimated to affect around 7 out 100,000 people around the world. As the name suggests osteogenesis imperfecta is characterized by imperfect formation of the bones that leads to frequent fractures or breaks from minor trauma (Rauch et al., 2004). Depending on the severity of symptoms the impact to an affected individual 's life can differ. This paper will…

The assigned sequence was most closely matched via the BLAST algorithm with the retrieved sequence of Trypsin-1, accession no P07477.7 [1] (Appendix 1). Trypsin-1 is a 247 amino acid long protein [2] (Appendix 3) of the serine protease family, with a molecular mass of 26,558 Daltons [3] (Appendix 2). It is globular in shape and contains two regions of α-helices and multiple regions of β-sheets, as seen in Figure 1[4]. It contains disulphide bonds at residue positions 30/160, 48/64, 139/206,…

To be specific, it helps control the “regulation of vascular tone, homeostasis of blood pressure and proliferation of vascular smooth muscle cells” (CITE). The hempseed has a rich content of linoleic acid, which reduces the cholesterol level of the body, and low cholesterol helps decrease the risk of heart attack. It also contributes in regulation and avoidance of blood pressure. (Rodriguez-Leyva and Pierce). Their arguments mainly focus on the contribution…

Alongside CRISPR-Cas9 in site specific genome editing are ZFNs and TALENs. ZFNs are a DNA-binding motif assembled as ββα that utilizes a roughly thirty amino acid protein with DNA recognizing amino acids at the alpha helix (Gaj, Gersbach, & Barbas, 2013). These groups of amino acids usually recognize DNA in segments of three. This does not present much specificity in a genome. Therefore multiple DNA-binding motifs need to be combined to create specificity and result in highly specific…

the body’s main source of energy for healing and for cell repair and for proper brain function. Some fat is also essential in every diet. Typically, the recommend amount of total fat is 30%. Unsaturated fat such as omega -3 fatty or omega – 6 fatty acids is encouraged instead of saturated fat. We do, however, need to monitor blood glucose levels since elevated blood glucose make wound healing more difficult. When glucose levels remain high over time, wounds may…

Discussion: The specific purpose for this study was to see how enzyme activity would change as there was a change in temperature and pH. Both temperature and pH were hypothesized to have an affect on enzyme activity. Each had an optimal temperature. At this point, the rate of enzyme activity would stop increasing and begin to decrease. For temperature, it was hypothesized that the optimal temperature would be 48°C. For pH, it was hypothesized that the optimal pH would be 7. As temperature was…

My journey starts in Rwanda, a small country in East Africa. It started after I excelled in the national examination, an exam for high school students pursuing college admission, and got rewarded a scholarship to study college in the US. The experience I gained throughout my scholarship period, research, and background inspired me to pursue graduate studies. This goal has been an important reason for both my education and life pathways. In Rwanda, my country of birth, there is a presidential…

nutritional supplement commonly used with athletes. This supplement is found almost entirely in skeletal muscle. Here, energy is fueled and bursts needed for the explosive contractions (such as weight training) are met. This supplement is formed from amino acids and plays a role in converting food into energy. Creatine is becoming more popular amongst the use of younger (under the age of 18) athletes. However, is it safe? Is there enough information about it? There is little research about the…

In this study, we analyzed the bulk of genomic and transcribed CsRn1 sequences encompassing the putative frameshift region in C. sinensis and Opisthorchis viverrini, which is a nearest phylogenetic neighbor of the liver fluke, to address the issue regarding the expression strategy of CsRn1. Our results demonstrate that CsRn1 copies lacking frameshifting have arisen from the precedential counterparts with two overlapping ORFs by a single-nucleotide insertion at an upstream region of gag stop…