Solubility equilibrium

chemical compound forming. This experiment was done to determine the identity of the nine unknown solutions like color (physical trait), and chemical characteristics. Of course to determine the identity of this nine unknown solutions a sequence of solubility tests…

1) Important solubility characteristics for a solvent to be used in the crystallization of an organic solid that’s contaminated with impurities is that the organic solid should have low solubility at low temperatures in the solvent, but highly soluble at high temperatures. Also, the solvent should allow the impurities to be either completely soluble or completely insoluble at all temperatures. 2) One way to improve our percent recovery is by making a second crop of crystals by removing the…

Results and discussion: 1. Screening of ME components: 1.1. Solubility of sulpiride in ME components: In order to achieve maximum drug loading into ME formulation, the oil, which showed higher solubilization capacity for sulpiride is selected for ME preparation. The choice of oil for ME is often a compromise between its solubilization potential for the drug and its ability to microemulsify. Results in table 1 represent the solubility of sulpiride into different oils, surfactants and…

2.1 Polydimethylsiloxane (PDMS) Polydimethylsiloxane (PDMS) own to a group of polymeric organosilicon compounds that are commonly stated as silicones. PDMS is optically clear, and, in general, non-flammable, non-toxic, and inert. PDMS is viscoelastic, meaning that at long flow times (or high temperatures), it acts like a viscous liquid such as honey. However, at short flow times (or low temperatures), it acts like an elastic solid such as rubber. In other words, PDMS will flow to cover the…

Section Two - Oral Liquid Formulations (1) Characteristics of Suspensions: The oral liquid dosage form chosen to formulate was that of a suspension. Given the criteria of Drug Y it was thought best to formulate the drug as a suspension. Suspensions can be defined as ''a class of materials in which one phase, a solid, is dispersed in a second phase, generally a liquid.'' (1) There are many characteristics of suspensions that are relevant when formulating such a dosage form. They are as follows;…

EXTRACTION OF A KNOWN MIXTURE Separation of mixture of Acetyl salicylic acid (aspirin) and naphthalene Experiment # 6 Introduction A technique called extraction will be demonstrated in this experiment. Extraction relies on the solubility of substances into solvents and the insolubility of the solvents into each other. In this experiment, three organic compounds (aspirin and naphthalene) will be separated from each other. The two compounds are all soluble in ethyl ether (an organic solvent). By…

Case study one 1. Principle of APTT: Platelet poor plasma (PPP) is incubated at 37 degrees Celsius then phospholipid (cephalin) and a contact activator (e.g.: Kaolin, ellagic acid) are added followed by calcium (all pre-warmed to 37 degrees Celsius). Addition of calcium initiates clotting and timing begins. The APTT measures the time required to regenerate thrombin and fibrin polymers via the intrinsic and common pathways. Reagents:  Platelet poor plasma (PPP)  Surface activator: example;…

1. Materials and suppliers • Caffeine (anhydrous), BASF, Germany, was generously donated by Dar Al Dawa Development and Investment Company. Caffeine is 1,3,7-trimethyl-3,7-dihydro-1H-purine-2,6-dione. It is white or almost white, crystalline powder or silky crystals. It is sparingly soluble in water, freely soluble in boiling water and slightly soluble in ethanol. It is used as central nervous system stimulant (British Pharmacopoeia 2009). • Methyl paraben was generously donated by Arab…

3. SAFETY AND ENVIRONMENTAL ASPECTS OF SULPHURIC ACID PRODUCTION 1. Safety Aspects 1. Basic Safety Aspects due to Physical properties and behaviour of Sulfuric acid. Basically, we know attention is paramount when adding water to a highly concentrated acid and this is the case with sulphuric acid which is highly risky. Sulfuric acid can have serious adverse effects like burns if it contacts the skin. This is due to the dehydrating properties of the acid on organic materials. Also, when the…

FT-IR analysis. Figure 1 shows infrared spectra of CNC, CNC treated with HCl and CNC treated with NaOH. This Data suggests that there are no significant changes in the structure of CNC due to extreme acid and basic media exposition. All the major vibration modes remained unchanged, this included 3330 cm-1 broad band corresponding to OH stretching, 2890 cm-1 due to CH2 and CH asymmetric and symmetric stretching, 1638 cm-1 related to the bending mode of absorbed water, 1430 to 1330 regions…