Difference Between Separation Of Aspirin And Naphthalene

Improved Essays
EXTRACTION OF A KNOWN MIXTURE
Separation of mixture of Acetyl salicylic acid (aspirin) and naphthalene
Experiment # 6
Introduction
A technique called extraction will be demonstrated in this experiment. Extraction relies on the solubility of substances into solvents and the insolubility of the solvents into each other.
In this experiment, three organic compounds (aspirin and naphthalene) will be separated from each other. The two compounds are all soluble in ethyl ether (an organic solvent). By selectively reacting each organic compound, we can make it soluble in water and insoluble in ethyl ether. Since ethyl ether and water are insoluble in each other, they will form two phases and can be separated from each other using a separatory funnel. The reacted organic compound
…show more content…
Close the stopcock and repeat the shaking - pressure release procedure until no further pressure build up is noticed. This will indicate the aspirin/NaHCO3 reaction is completed.
Extraction of Aspirin
1. Place the separatory funnel into the ring stand to hold the funnel upright.
2. Remove the stopper from the funnel.
3. Open the stopcock on the separatory funnel and draw off the lower aqueous portion of the liquid into a 125 ml Erlenmeyer flask.
4. Since some of the aqueous solution is still dissolved in the ethyl ether, add an additional 20 ml portion of 5% NaHCO3 and repeat the extraction procedure. Combine this second aqueous portion with the first 5. Place the 125 ml flask into a warm water bath (60 C) and gently heat. This will evaporate any ether still present in the aqueous portion. Do not overheat.
6. Cool the aqueous solution to room temperature.
7. Carefully and slowly, with constant stirring, add 6M HCl with stirring until a pH of 1-2 is indicated by pH paper. The HCl will convert the water soluble salt into the insoluble aspirin. The aspirin will start to precipitate out as the pH is reduced.
8. Vacuum filter the aspirin using a Hirsch funnel and use ice cold water to

Related Documents

  • Improved Essays

    Therefore –OH is ortho, para directing and -NH2 is meta deactivating. With all this in mind, positions 3 and 5 are more likely (on carbon 2 and 4 on the NMR). 5 is more likely and not 3 because of steric hindrance. Experimental In a 100ml round bottomed flask, salicylamide (2.0g, 14.6mmol, 1eqiuv) and sodium iodide (2.4g, 16mmol, 1.1equiv) were dissolved in absolute ethanol (40ml). The solution was stirred and cooled to 0°C using a water bath.…

    • 960 Words
    • 4 Pages
    Improved Essays
  • Decent Essays

    HCl slowly with stirring until the mixture is acidic to congo red paper. Collect the resulting crystalline precipitate of hippuric acid or benzoyl glycine , which contaminated with a little benzoic acid upon a Buchner funnel, wash with cold water and dry. Place the solid in the 100 ml beaker with 10 ml of CCl4 ,cover the beaker with the watch glass and boil the mixture gently for 5 minutes. Allow the mixture to cool slightly and filter by gentle suction and wash it 3-4 times with CCl4. Recrystallize it from the boiling water.…

    • 2234 Words
    • 9 Pages
    Decent Essays
  • Great Essays

    6. Restopper, rinse the top of the bottle to remove any acid and shake well until the precipitate has dissolved. 7. Titrate a volume of treated sample which corresponds to 200 mL of the original sample. This corrects for the loss of some sample during the addition of reagents.…

    • 4915 Words
    • 20 Pages
    Great Essays
  • Decent Essays

    Add 5 ml of hydrochloric acid along with 0.1 g of resorcinol. Shake the test tube well and place it in a boiling water bath for 5 min. Appearance of red color indicates the presence of added cane sugar in milk.  Dark brick red color indicated adulteration. (-ve) (+ve) Fig:- 2 B.…

    • 2449 Words
    • 10 Pages
    Decent Essays
  • Improved Essays

    The plate was placed into a mixture of dichloromethane and hexane and allowed to elute. Through capillary action, each solution and the solvent travelled up the TLC plate (Setzer, W., 2008). The solvent travels past each spot on the plate and while the polar silica gel tries to hold the spot in place, the solvent tries to move the spot with it as it travels up the plate. After removed from the solvent, the plate was placed into an iodine chamber in order to be able to visualize the distances the solutions travelled. The crude oil had two spots develop since it contained both Eugenol and eugenol acetate.…

    • 481 Words
    • 2 Pages
    Improved Essays
  • Improved Essays

    Bacillus Subtilis

    • 1799 Words
    • 8 Pages

    Using flamed forceps, dip a paper disc into the Dettol. Drain the excess liquid from it, then place it on the dish labelled A. Flame the forceps and repeat the steps for Ethanol, Salicylic acid and distilled water. Replace the lids as soon as possible. Tape and label the dishes with your names and the date. DO NOT INVERT THE PLATE.…

    • 1799 Words
    • 8 Pages
    Improved Essays
  • Great Essays

    Do not remove the thermometer and the stir wire. Transfer the solid from the weighing boat into the cyclohexane, stir well to obtain clear Solution 1. All solid must dissolve, including any on the walls of the large test tube. 13. Close the large test tube, and adjust the thermometer and the stir wire.…

    • 1578 Words
    • 7 Pages
    Great Essays
  • Improved Essays

    Spinach Lab Report

    • 733 Words
    • 3 Pages

    [1] Water will move toward the more hypertonic solution and separate from the DCM extract. After successful separation of the pigments from the spinach leaves, the pigments are put into silica gel and the solvent is allowed to evaporate off so that the pigments (now in powder form) can be put through column chromatography to separate the chlorophyll and β-carotene pigments. Column chromatography is a means to divide chemical compounds from a mixture. Separation is achieved by eluting solvents through the column which hold similar properties to one or the other pigment. Chlorophyll, being a polar molecule, moves through the stationary phase of the column only when a polar mobile phase is added.…

    • 733 Words
    • 3 Pages
    Improved Essays
  • Improved Essays

    Urea Synthesis Lab Report

    • 988 Words
    • 4 Pages

    This liquid effluent is let down to 27 atm and fed to a special flash-evaporator containing a gas-liquid separator and condenser. Unreacted NH3, CO2 and H2O are thus removed and recycled. An aqueous solution of carbamate-urea is passed to the atmospheric flash drum where further decomposition of carbamate takes place. NH2COONH4 2NH3 + CO2 The pressure is then reduced and a solution of urea dissolved in water and free of other impurities remains. At each stage the unconsumed reactants are absorbed into a water solution which is recycled to the secondary reactor.…

    • 988 Words
    • 4 Pages
    Improved Essays
  • Improved Essays

    Isobutylene Research Paper

    • 1817 Words
    • 8 Pages

    It is a dehydrogenation unit that used to convert isobutane produced from the Butamer to a new compound that is Isobutylene. One of the vital points that must be considered is the feed, which enters this unit. The feed gas must be free of impurities that damage the platinum catalyst. Producing Isobutylene is summarized in the following stages. At the beginning, the isobutane that fed to the Oleflex unit is stored in Isobutane Sphere (V3103).…

    • 1817 Words
    • 8 Pages
    Improved Essays