A reaction mixture containing 0.5172g of boric oxide and 1.0167g of acetylacetone was prepared and mixed in a 10 mL beaker. The reaction mixture was heated with occasional stirring for 10 minutes. Next, another mixture containing 1.3321g tributyl borate, 3.0005g of vanillin and 15ml of ethyl acetate was prepared in a 50 mL conical flask. The mixture was mixed and a magnetic stirrer was added to the mixture. The mixture was then stirred on a hot plate for 5 minutes at room temperature. After…
Section Two - Oral Liquid Formulations
(1) Characteristics of Suspensions:
The oral liquid dosage form chosen to formulate was that of a suspension. Given the criteria of Drug Y it was thought best to formulate the drug as a suspension.
Suspensions can be defined as ''a class of materials in which one phase, a solid, is dispersed in a second phase, generally a liquid.'' (1)
There are many characteristics of suspensions that are relevant when formulating such a dosage form. They are as follows;…
All American EFX Kre-Alkalyn (pH-Correct Creatine) This is the brand that started is all on June 4th, 2002 when Kre-Alkalyn® was awarded United States manufacturing patent #6,399,661.
Kre-Alkalyn® EFX is "buffered" creatine that does not convert into creatinine prior to reaching skeletal muscle tissue. It is packaged in a purple capsule that can be administered orally. Kre-Alkalyn® EFX is manufactured exclusively by All American Pharmaceutical Corporation.
Why a critical adjustment to…
Synthesis of PEG-RAFT agent
The synthesis of the macro PEG -RAFT agent, Chain Transfer Agent (CTA), was performed by esterification method. Briefly, RAFT agent (0.4 g, 1.5 mmol) and dihydroxyl PEG (2g, 0.5 mmol) were dissolved in 35 mL of DCM in a 250 mL round bottom ﬂask equipped with a magnetic stirrer. Then, it was placed in an ice bath (0 ºC); Next, DCC (0.25 g, 1.2 mmol) and DMAP (0.015 g, 0.12 mmol) were added. After 30 min of stirring at 0 °C, the reaction temperature is elevated to room…
vinegar, bromothymol, sodium hydroxide and Lugol was shared throughout the
classroom by other classmates.
Before the labs began, we initiated by labeling the two trays. The four-well tray reagent
tray was labeled with tea, starch, MOM and 0.1 M Acetic Acid. The three-well reagent tray was
labeled in number from one to three. We then dedicated a pipet for each tray as well as
distributing other liquids to other trays. The first lab focused on changing the concentration of
The purpose of the experiment was to determine the density of powdered grape.
The company Gatorade has advertised that G2 powder replenishes fluids and electrolytes in the body’s blood stream during exercise. G2 has aided in staying hydrated, “maintain normal muscle performance, heart rate and brain activity” (1). In relation, there has been a rise in sports drink purchase to improve athletic performance. The experiment examined a basic level of G2 powders composition, the…
the Diels-Alder reaction will be performed by reacting (E,E)-2,4-hexadien-1-ol with maleic anhydride without the use of a solvent to make the reaction more greener. The reaction will be tested for the presence of a carboxylic acid in the product, to make sure the reaction proceeded as expected, with the use of sodium bicarbonate (NaHC"O" _"3" ).
Reaction 1: Diels-Alder reaction of maleic anhydride and (2E, 4E)-2,4-hexadien-1-ol…
How does red cabbage indicate the pH Level of different types of chemicals?
A solution is a mixture of a soluble chemical dissolved in water. Think about the difference between salt water and tap water. The salt in the salt water has dissolved and the solution looks clear, but the salt is still there and will taste salty if you taste it. Because solutions are made with water, which is made of hydrogen and oxygen, the hydrogen in the water can make a solution…
Four different were gathered from the IR spectroscopy to identify the nitrophenol. The first peak observed was a weak and broad at 3314.75 cm-1, which was corresponded to an alcohol group; therefore this peak must be corresponded to the O-H stretch of the phenol with a literature value that ranges from 3550-3500 cm-1 (Figure 5). The variance between the observed value, and the expected value can be due to the MHz of the IR spectrometer used. The second peak observed was a weak-medium, sharp and…
The steps of synthesis process can be explained in Fig. 1.
The Zn (NO3)2.4H2O (zinc nitrate tetrahydrate) and
Al (NO3)2.9H2O (aluminum nitrate nonahydrate) (Merck)
are used as a precursor. ZnO precursor solution with the
concentration of 0.15 M was made by dissolving 0.89 grams of
powder precursor Zn(NO3)3.4H2O in 40 ml of solvent. Solvent
comprises a mixture of 30 ml deionized water and 10 ml of
ethanol. To speed up the process of dissolution, the mixture
was stirred using a magnetic stirrer…