Carbon monoxide poisoning is fatal. Carbon monoxide binds to haemoglobin at the same site as oxygen – the iron atom within the haem group – however carbon monoxide will bind with a strength 200 times that of oxygen. This means that if carbon monoxide is inhaled it was always displace oxygen within haemoglobin. If oxygen can no longer bind to haemoglobin then the respiring cells of the body can no longer receive oxygen and will eventually die. When carbon monoxide binds to haemoglobin it causes…
CHAPTER 1 TIN OXIDE 1.1 Introduction Tin dioxide, also known by the systematic name tin(IV) oxide and stannic oxide in the older notation, is the inorganic compound with the formula SnO2. The mineral form of SnO2 is called cassiterite, and this is the main ore of tin. With many other names, this oxide of tin is the most important raw material in tin chemistry. This colorless, diamagnetic solid is amphoteric. 1.2 Structure It crystallises with the rutile structure, wherein the tin atoms are six…
NANOCARRIERS AS PROMISING NOVEL SYSTEMS FOR CONTROLLED DELIVERY OF DICLOFENAC SODIUM [N.B: Authors' details blinded by Pro Journals for Review] ABSTRACT The formulation and evaluation of Diclofenac sodium from liposomes, niosomes and nanoemulsion are analyzed. The release profiles of Diclofenac sodium were almost similar in all the formulations. It is found that 85% of Diclofenac sodium diffused out from the colloidal systems within 8hrs and practically all the drug was released within…
0.05. Thus, 4 hours extraction can be used in further extraction using methanol as solvents instead of 5 hours. This condition yielded the oil extractability below 20% and the oil extractability was not very high. This might be due to the poor solubility of some portions of triglyserol in oil with an extensive disulfide bonding and aggregation (Hamada, 1997). Moreover, the triglyserols in rice bran oil are a complex mixture and could bind with other compounds in rice bran such as phytate,…
Most amino acids are encoded by more than one codon. There are 64 total codons, three of which are stop codons, with 61 of the codons coding for 20 different amino acids. These codons, however, are not used equally. Codon Bias is defined as the deviation from equal usage of synonymous codons. Studies by Jan C. Biro found that the number of synonymous codons shows a significant correlation with the frequency of their respective amino acids. Furthermore, the redundancy of these codons may be…
Blood counts can reveal and abnormal Hb level in the range of 6 to 8 g/dl. Blood films may show RBC’s that appear as irregularly contracted cells. Sickle solubility test looks for the presence of Hb 5. What is Sickle Cell Trait? Sickle cell trait is an condition in which both hemoglobin A and S are produced in the red blood cells. The types of hemoglobin a person makes in the red blood cell depend upon what…
Statins represent a class of cholesterol-lowering agents used for the treatment of dyslipidemia (abnormal amount of lipids) and the reduction of atherosclerotic cardiovascular disease risk. Their broad and potent effects on the lipid profile and cholesterol-independent pleiotropic cardioprotective effects positioned them among the most prescribed medications worldwide. Statins were introduced in the late 1980s and early 1990s as a novel group of cholesterol-lowering drugs in attempt to offer…
Addison Bollaert Professor Hunderman Comp 252 4/6/15 Fukushima The nuclear arms race of the 1940s gave birth to countless advancements in science and technology. A seemingly limitless source of relatively clean energy had been discovered. Nuclear power did not come without risks, as the smallest error could lead to a disaster of unimaginable proportions. The events at Fukushima served as a reminder that when . The Fukushima Daiichi disaster will have lasting effects on the environment, and the…
The objective of work was to optimize, formulate, evaluate and compare the transdermal gel containing vesicle based: Transfersomes and liposomes, containing Ketoconazole, an anti-fungal bioactive. Ketoconazole loaded Transfersomes were prepared using thin film hydration method with different concentration of surfactant (Span80, Tween80, and Sodium Deoxycholate) and soya lecithin and characterized for various parameters including Vesicles Size, Morphology, Entrapment Efficiency, Drug Loading…
rely solely on the lemon juice. Despite our best efforts, we could not find anything on the Internet that had data on the Ksp value of calcium phosphate in a lemon juice solution. To determine the solubility of the calcium phosphate, we used an ICE table and from there were able to calculate solubility for both NaPO4 and CA (NO3)…