Solubility

developed including HPLC technique, using various mobile phases. In the development of analytical method it is extremely important to understand the solubility of an analyte. Tamoxifen citrate is very slightly soluble in water (0.3mg/mL at 20°C; pH 3.0-3.5) with high log P value (6) and is soluble in methanol (50 mg/ml). It also shows pH dependent solubility. (Vamsi,2013) The wavelength selected for analysis was 265nm to reduce baseline noise at absorption maximum (257nm) of Tamoxifen citrate.…

modified starches composed of glycopynanose units which form a ring of either six (α-cyclodextrin), seven (β-cyclodextrin) or eight (γ-cyclodextrins) units. Characteristics of β-cyclodextrins include: • Glucose unit: 07 • Molecular weight: 1135 • Solubility =1.85g/100ml • Cavity diameter = 6.4 Ǻ • Diameter of outer periphery = 15.4 Ǻ • Approx. volume of cavity = 262 (Ǻ)3 Cyclodextrins have a cylindrical shape with central axial cavity and resembles the shape of a truncated cone. The outer…

Abstract A Friedal-Craft reaction was performed to synthesize 1,4-di-t-butyl-2,5-dimethoxy-benzene from p-dimethoxybenzene and t-butyl alcohol. The product of the reaction was filtered using a Hirsch funnel, before recrystallizing and filtering a second time. The recorded mass of the product was .08g and the melting point was 47-52.7 °C. Introduction1 This experiment was designed to practice working with electrophilic aromatic substitution reactions. Specifically, a Friedel-Craft reaction was…

Water is the most important substance in a human’s life as it is the thing he needs to survive. It makes up around 73% of the human body and around 80% of the earth. Water has many characteristics that are linked to its uses and that make it useful and important to us. The structure of water is two hydrogen atoms covalently bonded to an oxygen atom . The oxygen atom has a valency of 6 which means that it has 6 electrons in its outer shell while each hydrogen atom has 1 electron in its outer. The…

Abstract: The melting point ranges for the substances Tartaric Acid, Acetaminophen, and Phenacetin, which are in powder form and white in color, was found and compared to their literature values to find their purity. The melting point range of a 9:1 mixture of Phenacetin and Tartaric acid was later found to show the effect an impure substance has on temperature. Melting point range for unknown three that was lastly tested was matched to Acetaminophen by comparing their melting points.…

body does not have the enzymes to digest fiber, a type of carbohydrate. It passes through the body without being broken down and helps to lower glucose and cholesterol levels and avoid constipation. Fiber divides in two categories depending the solubility in water; soluble and insoluble. The RDA for Fiber varies with age and…

3. Results and discussion 3.1. Microstructural and EDX analysis Fig. 1 and 2 show the surface morphology and EDX spectrum of FC and alum, respectively after coagulation/flocculation. The EDX analysis shows the adsorption of CB on FC and alum. As determined by EDX, detailed chemical composition of the dried flocs of FC and alum are presented in Table 1 and show that major elements of FC flocs are N, Fe, O, Cl, and of alum are N, Al, O, K, O, S. The weight % of element N defined the…

Color is usually gives the consumer the first impression about the quality of a given food product. It was reported that the lighter the color of mince fish product, the greater acceptability the product will receive (Lee, 2011). Color score values of common carp fish fingers during frozen storage are shown in (Table 8). The results indicated that color score values of the fresh control fingers sample and those prepared by incorporation of 10% (soybean flour (SF) (S) and 10% SF+1% pectin (M),…

The Carbon Cycle Addition of carbon to the atmosphere Respiration: Through respiration, carbon dioxide can be added to the atmosphere. Living organisms use respiration to turn food into usable energy. Aerobic respiration requires oxygen to take place, and produces carbon dioxide, releasing it into the air and atmosphere. The energy taken from the food molecules following digestion is used to fuel the organism, additionally when mixed with oxygen, releases carbon dioxide when exhaling.…

“Fluanxol”  Introduction : • History and background : - Fluanxol is a thioxanthene derivative which contains flupentixol as active substances. It belongs to group of medicines known as antidepressants drugs which act on nerve pathway in specific areas of the brain and help in correcting some chemical imbalances that cause the symptoms of this illness. - Its International Non-proprietary Name (INN) is flupentixol , but its British Approved Name (BAN) is flupenthixol and it is known in the market…