Carcinoma

Basal Cell Carcinoma is a type of skin cancer. The main cause of the illness is ultraviolet light, which is found in sunlight, tanning beds, and tanning lamps. A spot infected with Basal Cell Carcinoma could have several different appearances. One example is a flat, pale yellow area that is very similar to scar. Another appearance is a reddish, itchy patch, that may appear to just look like a rash. Others might look like pink or red bumps with darker areas in them, or open sores that won’t heal…

Head and neck squamous cell carcinoma (HNCCC) is the sixth most common cancer known worldwide with an incidence of 0.5 million new cases diagnosed annually, around half of these cases are oral squamous cell carcinoma (OSCC) (Jithesh et al., 2013). Though numerous risk factors have been implicated in the development of OSCC , the most important are tobacco smoking, alcohol consumption and betel-quid chewing (Petti et al., 2013). Evidences suggested that viruses are involved in oral…

Nasopharyngeal carcinoma (NPC) is a high incident in select geographic and ethnic population of south china, and the migrant Chinese in South East Asia and worldwide1-3. It is 6.4 in male and 2.4 in female per 100,000 in SEA region as the first rankof the world in a 2012 especially highest incident in Malaysia, Indonesia and Singapore4, however in Thailand, it is the high incidence rate same as south-eastern China provincial region, Hong Kong, Philippines and India. The treatment outcome of…

Small cell carcinoma of the breast resembles small cell carcinoma of the lung morphologically and immunohistochemically. Many hypotheses have tried to explain the histogenesis of neuroendocrine cells in mammary tissues; the most recent explanation is that NEBC are derived from divergent differentiation of a neoplastic stem cell into both epithelial and neuroendocrine cells (7). Two other old hypotheses suggested that it is either derived from neural crest cells that migrate to mammary glands,…

Abstract Hepatocellular carcinoma (HCC), the most common primary liver cancer, is one of the dreaded complications of chronic liver disease. Recent experimental and clinical studies have revealed the pivotal role played by the alteration of gut-liver axis in the onset of chronic liver diseases, including HCC. Altered gut microbiota and endotoxemia are increasingly recognized as critical components in promoting the procession of chronic liver diseases and the development of HCC. Probiotics have…

Background: Oral squamous cell carcinoma is a challenging oncology problem. A reliable biomarker for invasion and metastasis in oral cancer patients remains to be more clarified. β-catenin acts as a structural protein at cell-cell adherence junctions and as a transcription activator mediating Wnt signal transduction. Altered β-catenin expression has been associated with loss of cell differentiation and acquisition of an invasive phenotype. Ubiquitin carboxyl-terminal hydrolase L1 (UCHL1) is an…

In the journal article, there is an evaluation in the study of CD45RO+ memory Tumor Infiltrating Lymphocytes (TILs) in non-small cell lung cancer (NSCLC). This study can have a great impact on today 's problem because lung cancer is considered to be one of the most lethal malignancy around the world. To find the most reliable guidelines for treatments, the TNM classification is the best determinant because it uses a combined data on tumor burden, cancer cells in regional lymph nodes and…

ATYPICAL PRESENTATION OF GASTRIC CANCER APPROACHED VIA RETROGRADE SINGLE BALLOON ENTEROSCOPY RUNNING TITLE Atypical presentation of Gastric Carcinoma AUTHORS Dr. N***** ********* M.D. Dr. H**** Y***** MBBS ABSTRACT Globally Gastric cancer is the fifth most common cancer. Regular screening and early detection has decreased incidence of stomach cancer has decreased in Western world in the last 10 years. The American Cancer Society’s estimates for stomach cancer in the United States for…

The etiology of hepatocellular carcinoma are still unknown but some risk factors have been recognized which are cirrhosis, hepatitis B or C, heavy alcohol use, obesity, diabetes, hereditary conditions such as hemochromatosis and intake of aflatoxin-contaminated food (arun j). Cirrhosis is the primary factor risk for developing HCC. Based on (), 90-95% of people who develop HCC have underlying cirrhosis. The cirrhosis is a condition where the normal liver tissue are replaced by scar tissue after…

cell carcinomas of the lungs, head and neck, esophagus, and cervix account for over 400,000 deaths per year. Finding a way to effectively treat this type of cancer is very important for the well being of people. In this primary research article, the authors attempt to find a mechanism by which squamous cell carcinoma proliferation and invasion are inhibited. They use the cell adhesion molecule 1 (CADM1), which is a tumor suppressor, to show that it is possible to prevent squamous cell carcinoma…