Nasopharyngeal Carcinoma Essay

Decent Essays
Nasopharyngeal carcinoma (NPC) is a high incident in select geographic and ethnic population of south china, and the migrant Chinese in South East Asia and worldwide1-3. It is 6.4 in male and 2.4 in female per 100,000 in SEA region as the first rankof the world in a 2012 especially highest incident in Malaysia, Indonesia and Singapore4, however in Thailand, it is the high incidence rate same as south-eastern China provincial region, Hong Kong, Philippines and India. The treatment outcome of the NPC patients has significantly improved due to the advances in radiotherapy and comprehensive chemotherapy strategies with the 5-year survival is currently increased to 80%5. Therefore, the clinical situation of recurrent nasopharyngeal carcinoma (rNPC) patients is complicated. These patients always have local or regional failure with or without distant metastasis. Recurrent tumors usually extensively damage surrounding tissue. In rNPC patients, physical status and immune system are generally poor because of prior treatment. A study of Lee from Hong Kong reported that 52% of patients developed rNPC within 2 years, and 39%, within 2–5 years6.
Precision imaging was role to support the diagnosis of
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The CTP could differentiate benign and malignant tumors in the head and neck region12 and there was the correlation of the microvascular density of head and neck squamous cell carcinoma and locally controlled of non-NPC (head and neck carcinoma) with the perfusion CT parameters13. Recently, the accuracy of CTP in detecting rNPC was presented and suspected the CTP will pay major role in follow-up NPC15 but there was still no precision in practice to early detection of

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