Carboxylic acid

The goal of this experiment was to perform a synthesis of aspirin/ acetylsalicylic acid from salicylic acid, using a chemical synthesis procedure. The synthesis involved breaking the bond with acetic anhydride, also required heat and a catalyst, phosphoric acid, in order to beak and extract the bond. The solution used water in order to purify the solution in the way of recrystallization. The product was characterized using IR spectroscopy and melting point. The pure aspirin product that was…

3-(benzylideneamino)-2-phenylquinazolin-4-(3H)-one 5 (a-j) A mixture of 3-amino-2-phenyl-3H-quinazoline-4-one as well as its substituted analogs (3-4) and the appropriate aromatic aldehydes dissolved in ethanol (50 mL) containing few drops of glacial acetic acid were heated under reflux for 7-8 hr. The solution was cooled and the precipitated solid was obtain, filtered, and washed with water, dried in vacuum and recrystallized from ethanol 2, 3.…

It is obvious that the change in the buffer pH changed the retention times of the drugs slightly (Fig. 2e), Furthermore, the pKa values for VAL are 3.9 for the carboxylic group, and 4.7 for the tetrazole-NH group while for SAC, 4.6 is its pKa [17], so the chosen pH should be away from the pKa values of the compounds of concern. At higher pH than 7, broad peak of VAL was obtained. So pH 3 is the optimum pH to be used…

2.1. C. tomentosum extract characterization C. tomentosum extract proximal composition is shown in Table 1. The relatively higher ash proportion in seaweed extract (SE) (aprox. 74%) could largely be accounted for by the lower moisture content, and probably due to a hygroscopic nature of the SE (Blanco-Pascual, Montero, & Gómez-Guillén, 2014). The values of TPC and DPPH radical-scavenging activity are consistent with literature (Andrade et al., 2013; Valentão et al., 2010) (Table 1). POD and PPO…

would be moderately superior. Sodium bicarbonate will remain in an alkaline state which means the acidic properties will be also be removed and therefore the extraction of sodium bicarbonate will be fairly weak during the extraction phase. Carboxylic acid has a –COOH functional group whereas Paracetamol has a –OH functional which makes both of the functioning groups to react with Na only when NaCHO^3 is added to paracetamol and Aspirin. After this reaction, there will appear the production of…

Carbonate (NaHCO3) and Citric acid on the other hand react together in the aqueous solution to form sodium citrate. The sodium citrate produced is able to neutralise the HCl produced in the stomach by exchanging the H+ in the solution with the Na+ forming citric acid, which is a weaker acid than hydrochloric acid. There is also an excess amount of Sodium Bicarbonate present with solution and the bicarbonate ions act as the main buffering agents neutralising any acid or alkali added producing…

it is considered to be activating is because of the electron pairs on the ether molecule. Furthermore, the electrons activate the benzene ring which makes it more reactive. On the other hand, if benzoic acid replaced anisole in the experiment, it would act as a deactivating group. Carboxylic acid pulls electrons from the benzene ring acting as a withdrawing group which causes a slower reaction with the increase of stability and decrease in reactivity due to resonance. The electrophile is…

This objective was accomplished when the researchers synthesized esters of raspberry, banana and peach through reacting indicated alcohols and carboxylic acids in the presence of an acid catalyst in a round bottom flask and reflux condenser. This enabled the researchers to synthesize the following esters: pentan-2-yl acetate, benzyl acetate, butan-2-yl methanoate. The researchers, however, were unable to purify…

in the formulation of soap and also to produce the average quality of soap bar using basic formulations from palm oil. Generally, soap is a salt of a compound and it is known as a fatty acid. Most soap is produced either by using sodium or potassium. Its molecule has a long hydrocarbon chain with a carboxylic acid group…

Identifying Unknown Esters Produced by Fischer Esterification Introduction This procedure was performed in order to prepare an ester using an unknown alcohol and unknown acid via Fischer Esterification. Then to identify this unknown ester using gas chromatography. Esters are a derivative of carboxylic acids. In the Fischer approach, an acid is used in order to allow the esterification to occur. Gas chromatography separates compounds by their elution time. Data and Results The compound in the…