Tumor necrosis factor-alpha

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  • Rheumatoid Arthritis: The Cause Of Autoimmune Disease

    A deficiency in the female hormone, estrogen, will decrease bone restoration which could eventually lead to greater possibility of osteoporosis. This female hormone has an effect on bone cells and can impact the body through the endocrine system. It has been known that in order to develop rheumatoid arthritis it was most likely obtained through genetic factors rather than the environment or lifestyle. Each individual gene can contribute to the overall development of this disease. One gene that is a factor for rheumatoid arthritis development is the HLA-DRB1 gene. When this gene is paired with other variations of the gene then the likelihood of developing RA are…

    Words: 1155 - Pages: 5
  • Nephrotoxicity And Chloroplatin

    Nephrotoxicity is associate adverse effect of the anticancer drugs for solid and hematologic malignancies (Kintzel, 2001). Cisplatin, cisplatinum or cis-diamminedichloroplatinum (II) , a platinum-based drug, is one of the most frequently used anti-neoplastic agents. It has a potent anti-tumor action against wide range of malignancies, including testicular, ovarian, cervical, bladder and lung cancers as well as solid tumors resistant to other treatment regimens (Hanigan and Devarajan, 2003).…

    Words: 1345 - Pages: 6
  • Leaky Gut Essay

    of mice (Wang et al., 2013; Jarvelainen et al., 2000). The alcohol opens a pathway for the bacteria to travel into the portal vein where they are detected by the host’s immune system due to the bacteria’s identifying proteins. The binding of bacterial proteins and TRLs begins a cascade inducing pro-inflammatory tumor necrosis factor alpha (TNFα) to release into the blood plasma (Jarvelainen et al., 2000). The TNFα induces inflammation in the mice liver and intestinal cells, causing the…

    Words: 715 - Pages: 3
  • 2.2 Effect Of Pranayama Case Study

    significant decrease in the metabolic factors like fasting blood sugar, post-prandial blood sugar, HbA1c, triglycerides and LDL cholesterol levels in both groups T1 and T2. There was also a decrease in weight, BMI and waist to hip ratio in the test group. In addition group T2 showed a significant decrease in amount of insulin required per day. All these findings show us that there is a significant benefit of performing pranayama as a supplementary modality of treatment in patients suffering from…

    Words: 1106 - Pages: 5
  • Assignment On Clinical Pathology

    alleviate the symptoms of pain, swelling, and stiffness. The side effects are mild and include stomach problems and gastrointestinal bleeding. As the disease progresses, disease-modifying antirheumatic drugs can be prescribed to help slow the progression of the joint damage. These medications have more side effects, especially with long-term use. Short-term side effects include upset stomach, nausea, and diarrhea. Some long-term side effects of these drugs include increase risk of infection,…

    Words: 1900 - Pages: 8
  • Protein Intervention Methods

    demonstrate exercises which include light weight training to all study participants. This task will occur between August 1 and August 21, 2017. Measurement of knee strength will be accomplished through the use of a dynamometer which has been established as a reliable tool to measure strength in older persons.1 Study participants will be instructed on posturing throughout the measuring for knee strength and the assessment will be replicated three times using the mean was used for study…

    Words: 1521 - Pages: 7
  • Nfkb Essay

    and immune response to pathogens and tumor cells with age, ultimately affecting the external and internal milieu of the cell. With the decline in the immune surveillance activity of aging cells, the removal of pathogens and toxins decreases, the mutated senescent cells which are damaged and were earlier sensed and removed (through phagocytosis, autopahgy) tend to be accumulate, eventually resulting in build up of fertile ground for an active inflammatory response or a smoldering inflammatory…

    Words: 1437 - Pages: 6
  • Vete Case Study Essay

    Question 1 What are her risk factors for developing a VTE? (Identify all factors) Answer to Question 1 The risk factors that predisposes Mrs. X to develop a venous thromboembolism (VTE) are: advanced age, malignancy (cholangiocarcinoma), trauma (multiple falls), and recent major livery surgery (Schwartz & Rote, 2014, p. 1048-1050). Patients who are in their advanced ages are at risk in developing a VTE due to slower blood flow in their veins (Schwartz & Rote, 2014, p. 1048). Additionally,…

    Words: 1092 - Pages: 5
  • Monoclonal Antibodies Research Paper

    monoclonal antibodies allow them to bind only to the ill cells and destroy them without harming the healthy ones. Mammalian cells which produce a specific antibody are fused with tumor cells that can replicate endlessly. This fusion results in a “hybridoma”, a cell that can produce antibodies continuously. The antibodies produces by these hybridomas are called “monoclonal” because they derive from one single type of cell. [22] 2.2. Production of Monoclonal Antibodies: 2.2.1. Cellular Fusion:…

    Words: 2176 - Pages: 9
  • Ulcerative Colitis Case Study

    conventionally with 5-aminosalicylic acid (ASA), corticosteroids and oral immunosuppressant (e.g. azathioprine (AZA), 6-mercaptopurine (6MP)) with the goals of achieving clinical or mucosal remission, and/or eliminating long-term corticosteroid use [3]. Although, the conventional therapies are in many cases cannot be tolerated by the patients or ineffective. This failure of conventional therapy of UC patients is due to frequent of colectomies was performed; the percentage of colectomy cumulative…

    Words: 973 - Pages: 4
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