Metabotropic glutamate receptor

Disorders of sexual development (DSD) have been a topic of great interest as of late. Intersex, at its most basic definition, is when one does not ‘fit’ into the binary gender structure most commonly subscribed to in Western civilization; or, rather, having a variation of sexual characteristics or a combination other than the more common female to XX and male to XY. Research shows that 1.7% of the population has a DSD, considering the current population of the U.S., that would be approximately…

or specialized proteins that protect the immune system, which were most likely produced as part of the body’s response to the patients’ teratomas (Dalmau 63). Basically, teratomas contain various cell types that, when they cross-react with NMDA receptors, which can affect memory and learning in the brain, basically make one’s system vulnerable to a breakdown of the immune system. This creates a confusion in the body that produces autoantibodies which…

moderate to severe pain usually associated with postoperative pain or neoplastic disease. (Tiziani, 2010) Morphine produces pharmacological actions such as pain relief, by acting on receptors located on neural cell membranes. (News Medical, 2015) Morphine simulates the actions of endorphins and enkephalins at opioid receptors, (Bryant & Knights, 2011) The capabilities of morphine span further than just the treatment of pain, it can be used to supress an unproductive…

Causes The causes of Parkinson’s Disease remain unknown, however there have been several theories as to what could cause the debilitating disease. Factors such as age, and genetic predisposition play a major role in the development of the disease. The disease is most common in those over sixty, however, it could take over twenty years for symptoms to develop. Age is the most common factor in the development of the disease, however if the disease is detected early, then it is most likely due to…

Classified as a complex brain disease, SUD is treatable, according to the USA National Institute of Drug Abuse (NIDA) principles of treatment [NIDA, 2008]. Given the aforementioned multiple factors, contributing to the development of SUD, its complex presentation, and associated disease burden; treatment of SUD is rated as significantly challenging. Delivering effective SUD treatment and care requires a comprehensive response, illustrated as core services and interventions delivered, within a…

increasing levels cannabis metabolites leads to paradoxical vomiting seen with long term use6 .Cannabidiol is one of the metabolite which is a partial agonist at CB receptors thus acting as an agonist in lower concentration and antagonist at higher levels 6.Cannabigerol is a metabolite of cannabis which is antagonist of cannabis at the receptors .These metabolites tend to accumulate in chronic users and hence there is latency period before onset of symptoms in THC users6. Studies have…

The first receptor I will be doing is the Somatostatin receptor there is so much behind this receptor. Somatostatin (SST), otherwise called somatotropin discharge restraining variable (SRIF), is a hypothalamic hormone, a pancreatic hormone, and a focal and fringe neurotransmitter. Somatostatin has a wide conveyance all through the focal sensory system (CNS) and also in fringe tissues, for instance in the pituitary, pancreas and stomach. The different activities of somatostatin are intervened by…

activity can further validate an altered state of perception in caffeine-exposed bees (Wright et al., 2013). Moreover, while caffeine’s effect on calcium-mediated ryanodine receptors has been elucidated, its interactions with adenosine receptors remain elusive (Mustard, 2014). Caffeine is thought to antagonize adenosine receptors and influence the firing rate of neurons (Mustard, 2014). This can have an impact on the summation of…

(Advokat, Comaty & Julien, 2014). Although the exact cause of Alzheimer’s is unknown, it is hypothesized that two systems crucial for the communication between brain cells fail due to the down regulation of acetylcholine and the over activation of glutamate, which result in the death of neurons (IOS Press, 2008). It is believed to involve the irreversible loss of cholinergic neurons, specifically in the cerebral cortex and hippocampus (Advokat et al., 2014). The onset of this disease usually…

These receptors are found in the cardiac muscle and their stimulation has a positive inotropic effect (increases the contractility of the heart). It does so without significantly increasing heart rate or affecting peripheral vascular resistance (as it does not activate alpha adrenergic receptors of blood vessels). The result is increased cardiac output via increased stroke volume (Tariq & Aronow, 2015)…