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  • Conditioning Processing And Reflection Of Fear Memory

    C2A. Preliminary Results: C2A1. Establishment of fear conditioning protocols to study consolidation and extinction of fear memories: Presented below is published and preliminary data to establish feasibility for the proposed studies; the conditioning and extinction protocols are sensitive to manipulations that enhance or impair fear memory storage and the acquisition and consolidation of extinction. We reported (Zhang et al. 2013) that mice given post-training serotonin 2A receptor agonist TCB-2 (1mg/kg, open bar) exhibited significantly greater freezing than vehicle-treated mice (black bar) during a context test 24h after fear conditioning (A). These data indicate that activation of 5HT2A receptors enhances storage of fear memory. In a second…

    Words: 844 - Pages: 4
  • What Is Meant By Agonist In Muscle Pairs

    What is meant by “agonist and antagonist muscle pairs”? Give an example What is meant by agonist in muscle pairs is that it does the majority of the workload in an exercise and is considered the prime mover (primarily responsible for movement). The antagonist in respect to the agonist counteracts. The antagonist helps allow the agonist to perform a task. An example could be the biceps brachii contracts when doing elbow flexion. While the antagonist would be the triceps brachii relaxing during…

    Words: 1024 - Pages: 5
  • Triptorelin Research Paper

    Triptorelin: Product Description Triptorelin is a synthetic decapeptide hormone which falls under the gonadotropin-releasing hormone agonist (GnRH agonist) utilized as the pamoates or acetate salts. GnRH is Triptorelin (GnRH) initiates persistent stimulation of the pituitary glands and therefore leads to a decline in the levels of follicle stimulating hormone (FSH) and gonatropins luteinizing hormone (LH) secreted by the pituitary gland. It achieves this function by over stimulating the body’s…

    Words: 1034 - Pages: 5
  • Antagonists: The Classification Of Antagonists

    convenient to be applied in clinical practice. There are two main categories for antagonists based on whether they combine with receptors. The first type is receptor antagonists that are capable of binding to receptors to inhibit the possession of agonists but do not have intrinsic activity. Receptor antagonists are divided into competitive antagonists and non-competitive antagonists (Rang et al., 2007). The second type is non-receptor antagonists that have two main approaches to prevent…

    Words: 1361 - Pages: 6
  • Chronic Bronchitis Case Study Essay

    4. What is the rationale for treating R.S. with Theophylline and a B2 agonist? Typical treatments for individuals who suffer from COPD are to “block the progression of the disease, return the patient to optimal respiratory function and return the patient to their usual activities of daily living” (Copstead & Banasik, 2013). R.S. is currently being treated with an inhaled B2-agonist and Theophylline as bronchodilators. Theophylline excites the central nervous system (CNS) causing…

    Words: 1462 - Pages: 6
  • Salbutamol: Chiral Chemistry By Louis Pasteur

    Pharmacological activity of enantiomers of Salbutamol: Salbutamol, the most generally utilized short-acting β2-agonist, comprises of a racemic mixture of equivalent measures of two enantiomers, (R)-salbutamol and (S)-salbutamol. The bronchodilator impacts of salbutamol are credited altogether to (R)-salbutamol (levosalbutamol), while (S)-salbutamol has been demonstrated to have bronchospastic and expert provocative impacts both in vitro and in vivo studies. Levosalbutamol, the (R)-enantiomer of…

    Words: 2112 - Pages: 9
  • The Heterotrimeric G-Proteins

    have many nearby inactive G-Proteins. These G-Proteins are bound to GDP. The receptor is activated by an agonist,a hormone or chemical mediator. When the agonist binds to the receptor it causes a conformational change in the receptor. This allows the receptor to bind to a nearby G-Protein. This binding then causes the G-Protein to undergo a conformational change. Due to the conformational change the receptor bound G-Protein will release its bound GDP and replace it with GTP. The Gα and Gβγ…

    Words: 813 - Pages: 4
  • Case Study: COPD

    They are also used for short and long term relief of certain symptoms that come with COPD. ” Studies show that inhaled beta2-agonists are effective in treating symptoms of COPD and improving lung function as measured by tests (spirometry). They also reduce the number of COPD exacerbations (Celli, 2008). The preferred use of β2 agonists are through inhalation because they cause the smooth muscle relaxation. “Long-acting bronchodilators are preferred over short-acting ones because of fewer doses…

    Words: 1617 - Pages: 7
  • Bronchitis Case Study

    Theophylline has a longer acting and has anti-inflammatory effect, also appears to produce relatively constant levels of effect on airway responsiveness and clinical efficacy around the clock. Theophylline is use to prevent and treat wheezing, SOB, chronic bronchitis, emphysema and other lung diseases. In R.S.’s case it should be efficient because it helps open and relax air passages and makes it easier to breath. And B2 agonist is a shorter acting bronchodilator used for first defensive…

    Words: 808 - Pages: 4
  • Dexmedetomidine And Hypertension Case Studies

    words : Dexmedetomidine, Hypertension, Sedation. Introduction Dexmedetomidine, a highly selective centrally acting α2 adrenoceptor agonist…

    Words: 980 - Pages: 4
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