Metabotropic glutamate receptor

Additionally GLPP-1 receptor agonist treatment has shown reduction in the occurrences of hypoglycemia when chosen as a mode of treatment. Clinical trials were extensively conducted for about 84 weeks. In Comparison with Insulin Glargine, Exenatide QW lowered A1C level significantly…

unfortunately, two thirds of this population are between 12 and 17 years old (Sofuoglu, Sugarman & Carroll, 2010). Marijuana contains an active ingredient, tetrahydrocannabinol (THC) which alters the human central reward pathway by stimulating cannaboid receptors in the place of anandamide, a hormone of the endocannabinoid system, ultimately causing a sense of euphoria, a common attribute of other abused…

This essay illustrates the classification of antagonists according to their characteristics. The classification of antagonists is divided into two main categories, receptor antagonists and non-receptor antagonists. In receptor antagonists, it would be divided into competitive antagonists and non-competitive antagonists. In non-receptor antagonists, divided into chemical antagonists and physiological antagonists. In different categories, there are different examples to support the feature of the…

coming off. Ibogaine acts on almost all receptors in the brain, but primarily the…

Legendary musician Bob Marley once said, “Herb is the healing of a nation, alcohol is the destruction.” Bob Marley believed that smoking marijuana opened up a spiritual gateway leading him to become one of the greatest musicians and poets to live. A lot of people other than Bob believe that marijuana can be the answer to a lot of the world's problems. Many cannabis users today argue for the legalization of medicinal and recreational use of marijuana. Marijuana is shown to help with many…

anti-bacterial. Terpinolene has sedative effects. Outside the body it has shown to be a repellant of mosquitoes and weevils. Linaool Also found in lavender. Relieves anxiety and stress. Is a strong anticonvulsant and is said to amplify serotonin receptor transmission. Linaool has antidepressant effects and is effective topically to heal tissue and reduce scarring. Phytol Phytol is unique from other terpenes, offering other medical options. Phytol is the byproduct of decomposed chlorophyll.…

Albuterol is an adrenergic receptor agonist with pharmacological properties and therapeutic indications similar to terbutaline. The mechanism of the anti-asthmatic action of adrenergic receptor agonists is without a doubt linked to the direct relaxation of airway smooth muscle and the bronchodilator. Although human bronchial smooth muscle receives little or no sympathetic stoppage, it contains large numbers of adrenergic receptors. When the adrenergic receptors activate the adenylyl cyclase…

researchers were interested in determining whether sex differences exist for the cannabinoid modulation of appetite, body temperature, and neurotransmission at POMC synapses. The drugs that were used in this experiment were a 1 mg/kg s.c. agonist CB1 receptor WIN 55,212-2, a 3 mg/kg s.c. antagonist AM251, and a 1 ml/kg s.c. vehicle. This study had two parts to it with one focusing on the behavioral aspects of the animals and the other on the biological aspects. Behavioral…

1ml per sample. The samples were incubated at 4⁰C overnight. The following day, the samples were washed with DPBS at 4⁰C and then washed with 2ml 1 perm buffer twice. Anti-mouse Foxp3- PE Ab was added in a 1:100 dilution for 30 mins at 4⁰C. The samples were washed with perm buffer and resuspend in DPBS for flow cytometry analysis. Table 2.4 Antibody panel for SHPS-1 Phenotyping Panel PerCP FITC APC PE PB DC 1 CD45 CD11b CD11c CD103 B220 DC 2 CD4 CD11b CD11c CD8 B220 Treg CD3 CD25 FoxP3 CD4…

Did you know that whenever you smell something, it triggers your senses, and the brain? There are five senses, and one is smell. The brain is a important organ in our body, it tells our body what to do, and what to not do. The person who studied the senses was Linda B. Buck, and the people who studied the brain was the Egyptians. Your senses let you know what is going on around you. The brain is the control center of the body. All information we have about prehistoric cultures comes from…