Hemoglobin

Abstract: Hemoglobin is an iron-containing protein in red blood cells that enable the red blood cell to bind oxygen in the lung and transport the oxygen to tissues and organs throughout the body. Oxygen binds reversibly to these iron atoms and is carried throughout the blood. As part of the experiment, we computed the concentration of hemoglobin and iron in a crystalline blood sample by measuring the absorbance of the sample as methemoglobin and cynamethemoglobin at 450-650nm. Furthermore, the hemoglobin and iron concentration were also measured by means of volumetric analysis and the Wong method. The concentration of Hemoglobin and iron obtained in the experiment was in good agreement with their corresponding literature value. The computation for the error analysis suggests that the error in the concentration with respect to the absorbance contributed highly to the result, because without it, the concentration of hemoglobin and iron in the blood sample will…

transported by blood through the circulatory system. It is the hemoglobin inside the red blood cells that is responsible of binding the oxygen. A hemoglobin consists of four sub units and therefore it can be termed as a tetramer. This tetramer is made of two dimers known as alpha-beta dimers. Therefore, in total hemoglobin is made up of two alpha monomers and two beta monomer. Each of these monomers makes a subunit of a hemoglobin. Each of these subunits is responsible of binding and…

(SCD) is an inherited red blood cell disorder that is present at birth and is often more prevalent amongst African Americans.1 In order to inherit SCD, a person must inherit two abnormal hemoglobin genes, one from each parent. Hemoglobin is a protein found in red blood cells that is responsible for absorbing oxygen in the lungs and transporting it throughout the body.13 Proteins typically have four levels of structure: primary, secondary, tertiary, and quaternary. The primary structure of a…

Such as for the infections, doctors prescribe antibiotics to prevent or cure them. There are also some treatments to prevent the cells from becoming their sickle shape. One popular drug is Hydroxyurea, which will activate the genes that make fetal hemoglobin (Hoehn).Which is hemoglobin that will not form into a sickle shape. Another way to try to prevent the sickling of blood cells is to drink water and avoid dehydration, and avoid situations or conditions that will cause their oxygen levels to…

Red Blood Cells The red blood cells, scientifically known as Erythrocytes, are stored and developed in the bone marrow. The Erythrocytes make up around around 40 percent of the blood’s volume. In our body we have approximately 20-30 trillion Erythrocytes and every single one contain about 270 million hemoglobin. Hemoglobin is a protein filled with iron, which gives the blood its red color. Hemoglobin allows the Erythrocytes to carry oxygen through blood vessels from the lungs and bring it to…

having increased shortness of breath and decreased energy as well as low enthusiasm. Ms. A. reports a history of menorrhagia and dysmenorrheal for the last 10-12 years and for 6 days during her menstrual cycle she takes 1gm of aspirin every 3 to 4 hours. She also reports taking aspirin for stiff joints in the summer while playing golf. Lab results show a low hemoglobin of 8g/dl, hematocrit of 32%, and a erythrocyte count of 3.1 x 10/mm. The reticulocyte count of 1.5% is at the high end of…

of the beta-hemoglobin gene (beta S allele) in red blood cells [2]. Individuals who are diagnosed with sickle cell anemia have deformed (sickle shaped) red blood cells that have a lower lifespan [3]. This causes irreversible tissue damage and causes a vaso-occlusive crisis, which is pain in the abdomen, bones and chest and lungs. According to the Sickle cell Disease Association of Canada, there are currently an estimated 5000 individuals who are living with sickle cell disease and 1 in every…

(SCD) describes a group of inherited red blood cell disorders. Individuals with SCD have irregular hemoglobin, called hemoglobin S or sickle hemoglobin, in their red blood cells (RBC). Sickle cell anemia is a hereditary disease of the RBCs. Typically red blood cells are formed like a circular shape. This gives them the adaptability to go through even the tiniest veins. Be that as it may, in individuals with sickle cell, the red blood cells have a strange curve shape. When shaped like this it…

"Anemia is a reduction in the total number of erythrocytes in the circulating blood or a decrease in the quality or quantity of hemoglobin" (McCance & Huether, 2014, p.982). There are many causes of anemia and are classified in this manner. There are three classifications: macrocytic-normochromic anemia, microcytic-hypochromic anemia, and normocytic-normochromic anemia (McCance & Huether, 2014). Macrocytic-normochromic anemias encompass pernicious anemia and folate deficiency anemia (McCance &…

Sickle cell dieasese causes the body to create abnormal red blood cells. Normal red blood cells are typically shaped like a doughnut, as for sickle cells the abnormal cell has a C-shaped. In Sickle cell anemia, the hemoglobin in red blood cells clumps and stick together causing red blood cells to become stiff and form the C-shaped. When this occur the sickle cell blocks blood and oxygen flow. Anemia take place because the sickle cell breaks down more rapidly than normal red blood cell. Red…