Hemoglobin

microparticles derived from sickle cells deliver heme to the vascular endothelial cells causing oxidative damage. Sickle Cell Disease (SCD) is an inherited blood disorder caused by a single base mutation in the DNA of affected patients, producing abnormal hemoglobin molecules. In SCD, red blood cells (RBCs) that carry oxygen lose their flexibility and typical round shape, and become rigid with a distinctive “sickle” shape that make their passage through blood vessels more difficult. Millions…

level of hemoglobin (Porth, 2011). Hemoglobin, or HGB, is a protein in red blood cells that carries oxygen to organs and tissues throughout the body. Hematocrit, or HCT, is the volume of cells in 100 mL of blood (Porth, 2011). HGB and HCT levels can indicate the severity of the anemia. Mean corpuscular volume, or MCV, tells us the average size of the red blood cells. In this patient’s case, her MCV value indicates microcytic anemia as the level is lower than normal. Mean corpuscular hemoglobin…

history of chronic blood loss such as menorrhagia can develop iron deficiency anemia because so much iron is loss every month through heavy bleeding. Iron deficiency anemia can be corrected by taking iron supplement which can be started now. If the hemoglobin continues to drop, blood transfusion may be recommended for those who would accept it. Ms. A. has been dealing with menorrhagia for the past 10-12 years, which makes it a chronic…

More than 70,000 people in the United States have been affected with Sickle Cell Anemia. Sickle Cell disease is a genetic disorder that affects the red blood cells. The symtopms of the disease was first seen in 1904. The normal doughnut shape of the red blood cells become sickled making it difficult for these cells to transport oxygen throughout the body causing blockages resulting in extreme pain during a crisis. This diseases tends to affect african americans more than any other race, but…

Sickle Cell Anemia Dakoda Howard Indiana State University Pathophysiology 11/10/2016 Abstract The aim of this paper is to help individuals who do not understand or want to better their knowledge in Sickle Cell Anemia (SCA). SCA is commonly referred to as Sickle Cell Disease or SDA. The area of target is a general overview of that SCA, along with the various amounts of complications that can arise when someone has the disease. The paper will go over some of the more life threatening…

Sickle cell disease is a form of hemolytic anemia that is inherited; being caused by an abnormal hemoglobin molecule. There are several forms of SCD but the most severe is simply called sickle cell anemia; the dysfunctional hemoglobin molecule, called hemoglobin S (Hb S), assumes an unusual shape when it is subject to deoxygenation or dehydration (McCance & Huether, 2014). In a normal person, all hemoglobin molecules are shaped like…

Physiological Effects of Decreased Atmospheric Pressure At lower altitudes such as sea level, the main stimulation for ventilation is carbon dioxide. (7) At high altitudes, hypoxia stimulates ventilation. (7) However, hypoxia only stimulates ventilation when the partial pressure of inspired oxygen is reduced to roughly 13.3kPa, and is at an altitude of 3000m or more. (7) When the inspired partial pressure of oxygen is 13.3kPa, alveolar oxygen pressure is 8kPa. (7) As hypoxia continues to…

blood cells (RBCs) are lower than the normal in the blood. The function of red blood cells is to carry oxygen and eliminate carbon dioxide from the body. Another reason when an individual have anemia, if RBCs does not have sufficient amount of hemoglobin. Hemoglobin is an iron-rich protein that binds with oxygen and supply oxygen from the lungs to the whole body (National Heart, Lungs, and Blood Institute, 2014). Due to insufficient amount of iron, the blood…

inherited disease that is passed from the parents to the child. Both parents that carry the sickle trait or gene will pass the hemoglobin S gene to the child. There are six different forms of sickle cell disease type SS, SC, SB, SD, and SE. The more common form is Hemoglobin SS, which is the more severe form of sickle cell. In most cases children are born with Hemoglobin SS Sickle Cell Disease, meaning the child red blood cells will be sickle shaped and carry less oxygen to the organs. Normal…

Understanding oxygen supply and demand while working in the health care field is essential. The tissue cell mitochondria need to have adequate oxygen for metabolic consumption and ATP production. There are limited means of oxygen storage in the tissues; as such a continuous supply of oxygen is required. The respiratory and cardiovascular systems work together to make sure oxygen is delivered throughout the body, and that these continuous requirements are met. Exploring the main role of the…