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    Lou Gehrig's Disease

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    Amyotrophic Lateral Sclerosis, more formally known as ALS or Lou Gehrig’s disease, is a neurodegenerative disease, causing the selective degeneration of both upper and lower motor neurons, as well as those in the motor cortex portion of the brain, which ultimately leads to the limited to complete loss of all voluntary muscle function. Now while the main pathology of ALS is the selective death of the previously mentioned motor neurons, more recent studies have suggested that the homeostatic…

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    Central Pattern Generator

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    In the past, Walking or locomotion has been thought to be controlled by only the brain, and the spinal cord was merely a connector between the brain and the motor structure. The brain does control the voluntary muscle movement, but it works in conjunction with the spinal cord. It is now accepted that the motor patterns and rhythms governing locomotion in mammals are controlled by an area of the spinal cord known as the Central Pattern Generator (CPG) (Kiehn, 2006). The neural circuits in the CPG…

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    Many people have not heard of these diseases and maybe neither have you, but just imagine having to be a prisoner in your own body or losing your mind until you hurt yourself or someone else. When a disease like Amyotrophic Lateral Sclerosis (ALS) is diagnosed a person suffers from a progressive Neurodegenerative disease where their muscles slowly become weaker until they are bound to a wheelchair or a bed, but there is one thing that is unaffected and that is their brain. They stay conscious…

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    The nervous system is defined as the network of nerve cells and fibers that transmits nerve impulses between parts of the body. Amyotrophic lateral sclerosis (AKA ALS) is a progressive disease that attack the nerve cells found within the brain and spinal cord. On average 15 people a day are diagnosed with ALS, and on average patients die two to five years after diagnoses or early symptoms appear. The ALS Foundation’s goal is to find a cure for the fatal disease and provide relief to patients…

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    The Incident Amyotrophic Lateral Sclerosis (ALS), also known as Lou Gehrig’s disease is a progressive neurodegenerative disease that affects nerve cells in the brain and the spinal cord. This disease causes the brain to lose control of muscle movement and eventually leads to paralysis and death ("What Is ALS?," n.d.). College baseball player Pete Frates, who was diagnosed with ALS in March of 2012, came up with a way of spreading awareness of the disease (Gallo 2014). The challenge…

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    the reticulospinal tract causing rigidity of postural and girdle muscles. The last area of the motor circuit to be affected is the increase inhibition in the midbrain locomotor area causing decrease signals from the reticular formation to the spinal steeping pattern generators causing loss of automatic gait.…

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    fibrillary acidic protein (GFAP), cellular hypertrophy, and development of a pronounced stellate morphology (Lee et al., 2000; Liu et al., 2000; Messing and Brenner, 2003). Both beneficial and detrimental elements of astrogliosis have been described. In spinal cord injury (SCI), the stellate processes of astrocytes interdigitate to form a dense plexus that creates a physical and molecular barrier to nerve regeneration (Fitch and Silver, 2008; Ridet et al., 1997). Chronic demyelinated plaques in…

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    could better the scientific understanding of SMA that could lead to a breakthrough in treatment that will strengthen infant’s bodies, extend life, and lead to a cure for their illness. Topic: Today, I am going to discuss a horrible disease, called Spinal Muscular Atrophy that plagues our children in the world today. Importance: This disease is the number one genetic cause of death in infants in America today. Credibility: I have been actively involved in fundraising money for research after…

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    Sclerosis or “Lou Gehrig’s disease” is a neurodegenerative disease that affects nerve cells in the brain and spinal cord (What is ALS, Nov 30, 2014). Amyotrophic Lateral Sclerosis is a rapidly progressive disease that attacks neurons that are responsible for controlling voluntary muscle groups. Motor neurons are the neurons that are located in the brain (upper motor neurons), brain stem, and spinal cord (lower motor neurons). These different parts serve as communications links between the…

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    is more commonly referred to as Lou Gehrig’s disease after Lou Gehrig, a great American baseball player whose career unfortunately ended abruptly due to this incurable degenerative disease. ALS is the deterioration of motor neurons in the brain and spinal cord that leads to muscle weakness. This significant decrease in muscle strength eventually becomes paralysis, and the majority of those with this awful disease die from respiratory failure. This is the most common neuromuscular disease and…

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