Salicylic acid

skeleton. Thus, students hydrolyzed methyl salicylate (C8H8O3) to create salicylic acid (C7H6O3). For the second part of the lab (lab 7), students acetylated the phenolic hydroxyl group of salicylic acid in order to again demonstrate the same concept as lab 6. For both labs, students worked in groups of four and tasks were divided among group members. For the first lab, students converted methyl salicylate to salicylic acid through hydroxylation. In other words, methyl salicylate was boiled…

The goal of this experiment was to use the technique of thin layer chromatography (TLC) to identify the active analgesic ingredient of Advil and monitor the transesterification of methyl salicylate from acetylsalicylic acid. The synthesized methyl salicylate was then purified using acid-base chemistry and analyzed using H NMR spectroscopy. Identification of a proper mobile phase to separate common analgesics used in over-the-counter pain relievers was essential in being able to determine the…

Safety One of the main safety issues with the experiment involves the chemicals used in the reaction. The salicylic acid can cause irritation to the skin and eyes, cause cough or sore throat if inhaled, and cause nausea, vomiting, or ear ringing if ingested. Salicylic acid is also combustible and finely dispersed particles in air can be explosive (CDC Salicylic Acid, 2014). Acetic anhydride is corrosive and can cause severe irritation and burns to the eyes and skin, which can even lead to a…

oxygen3. Serratia Marcescens is a gram negative bacterium. Gram negative bacteria have a thin cell of a single layer of peptidoglycan that is enclosed by an outer membrane. The outer membrane is surrounded by special phospholipids composed of fatty acids called lipopolysaccharides that are attached to a glucosamine…

is a neutralization reaction. A neutralization reaction is a chemical reaction in which an acid and a base react to form an ionic compound (a salt) and water; the resulting pH is closer to 7. The general chemical equation for a neutralization reaction is: Acid + Base Water + Ionic Compound This can also be considered as a double displacement reaction. However, since the reacts are an acid (carbonic acid) and a base (sodium hydroxide) and the products are a salt (sodium carbonate) and water…

go to 7 or 7.8, it can be deadly. The blood buffer contains carbonic acid which dissociates into bicarbonate acid and hydrogen ions. This equation can also be reversed; it is a chemical equilibrium. If the hydrogen ions rise, bicarbonate accepts the hydrogen ions and the equilibrium shifts left thus making the blood acidic. When the blood becomes acidic, acidosis…

Introduction: Many chemical compounds are broken down into two very distinct categories: acidic or basic. Acidic, based on the Bronsted-Lowry Theory, is defined as a proton (H+) donor. An equation exemplifying an acid dissolving in water is: HCl (g) H2O H+ (aq) + Cl- (aq) A base, based on the Bronsted-Lowry Theory, is defined as a proton (H+) acceptor. An equation exemplifying a base dissolving in water: NaOH (s) H2O Na+ (aq) + OH- (aq) Molarity, also known as the concentration…

nanomechanical retention which is due to polymerisation of hydrophilic monomers around acid exposed collagen fibres.1 The entanglement of these monomers within the exposed collagen fibres gives rise to the so called Hybrid layer , which is also referred as Resin infiltrated Dentin layer.2 The presence of hybrid layer is important for attainment of a leakage free interface between the cavity walls and resin composite.2 After acid etching, the demineralized collagen matrix is present in a…

life. Pollution is creating a positive feedback loop in our freshwater aquatic life, including the killings of many of freshwater wildlife. Through the analysis of several different articles and books, this review will look over how eutrophication, acid rain, and heavy metal pollution effects freshwater aquatic life. Eutrophication is a process in which there are extra fertilizers, and other types of materials which runs off into…

on it which would have been removed with the stick. It is less clear why the benzoic acid was overproduced. Some of the organic layer may have been drawn off with it, but the vacuum filtration should have left only the benzoic acid. There could have been an error in weighing the filter paper before the procedure. There also could have been contaminants in the basic extract, causing more than just the benzoic acid to be filtrated. There is also the chance that too much starting material was…