Salicylic acid

Purpose The purpose of the experiment Thin Layer Chromatography was to analyze compounds, Aspirin, a mixture of Tylenol with ethanol, acetaminophen, a mixture of Excedrin with ethanol, Aspirin, and acetaminophen, Anthracene, Benzyl, and Triphenylmethanol by separating them with the help of silica plates. Procedure Three silica plates were taken and on the plastic side, they were all marked 1 cm above its end using a pencil. With the help of capillary tube, the first and the second plates were…

Introduction The ferric chloride test is used to determine the presence of phenols in a given sample or compound (for instance natural phenols in a plant extract). Enols, hydroxamic acids, oximes, and sulfinic acids give positive results as well. The ferric chloride test can be used to detect metabolites in urine in case of inborn error of metabolism such as phenylketonuria. In addition,the Ferric Chloride test can be used to detect salicylates in urine after an aspirin overdose.1 Background…

In order to extract aspirin, caffeine, and acetaminophen from a tablet of pain medication acid and base extraction techniques were used to exploit the differences in solubility between the components. This is achieved by using a separatory funnel and three different solvents, 4M HCl which separated the caffeine, deionized water which separated the acetaminophen, and 5% wt/vol NaHCO3 which separated the aspirin. Once the solution of the crushed tablet and ethyl acetate was mixed with a solvent in…

concentrated sulfuric acid in the first step? The purpose of using concentrated sulfuric acid is to activate the reaction of salicylic acid and acetic anhydride and produce the acetylsalicylic acid, which is aspirin. The sulfuric acid is used to protonate oxygen atom of a carbonyl group of salicylic acid. 2. What would happen if the sulfuric acid were left out? Removal of catalytic acid from the reaction would slow down or not proceed at all because the phenol group on salicylic acid is not…

system, and ionic character of solute. Ionic character and pH were manipulated to increase solubility favorability of the compound in extraction solvent. In essence, pH is the easiest factor to manipulate because it merely involves using an aqueous acid or base as an extraction solvent that simultaneously abides by the four solvent requirements of extraction. In regard to recrystallization, an impure compound is allowed to dissolved into a solvent and then allowed to reform as a pure solid…

Purpose: Determine the percentage of 2-ethanoylhydroxybenzoic acid in aspirin tablets. Introduction (including background information) : Before creating Aspirin, “sail alba” was used. In 1860’s, chemists discovered that Salicylic acid (2-hydroxybenzoic acid, C7H6O3 ) is the active acid in sail alba. Salicylic acid is relatively strong though. It can irritate and damage the stomach membranes and mouth. In 1889, ethanoate ester of salicylic acid was introduced by the Bayer Company. They named it…

aspirin Aspirin, also known as acetylsalicylic acid, is an aromatic compound containing both a carboxylic acid functional group and an ester functional group. Aspirin, being a monoprotic weak acid, is only slightly soluble in water and it can be prepared by reacting salicylic acid and acetic anhydride in the presence of an acid catalyst. 1.2: History of aspirin Aspirin was first produced about 110 years ago but the natural form, salicylic acid, found in plants (i.e. the willow and myrtle)…

aspirin from salicylic acid and acetic anhydride. The general theory behind this experiment was to study the synthesis of a drug from organic materials. During the experiment, esterification had occurred between reactants salicylic acid and acetic anhydride. Then, phosphoric acid would catalyze the reaction and water would be added to decompose the remaining acetic anhydride. Through the process of filtration, aspirin crystals were collected and separate from the liquid acetic acid-water…

the moles of reactants were calculated (Part A). Part B of the calculations illustrates the amount of aspirin produced by each reactant based on 1:1 mole ratio defined by the balanced equation of the reaction. According to these calculations, salicylic acid is the limiting reagent because it produces the least amount of aspirin. Thus, the limiting reagent, if fully consumed, dictates the theoretical…

Acetylsalicylic Acid from Salicylic Acid Shultz, Joshua T. Chemistry 2210L Data Figure 1. Esterification of Salicylic Acid to Yield Acetylsalicylic Acid Figure 2. Acetyl Group Table 1. Reference Data, Experimental Volumes, Yields, and Melting Points Melting Point of Salicylic Acid 158° C Melting Point of Acetylsalicylic Acid 138° C - 140° C Initial Mass of Salicylic Acid 0.510 g Theoretical Yield of Acetylsalicylic Acid 0.665 g Experimental Yield of Acetylsalicylic Acid 0.524 g…