psychotropic medications such as atypical Second Generation Antipsychotics (SGAs). As with most medications, there are often times adverse drug reactions (ADRs) may be present and these effects can be quite troublesome, diminish the quality of life, thus patient outcome. The decision to put patients on certain medications is often a risk versus benefit or based on harm reductions. Justification for this topic of interest is to improve staff knowledge regarding some of our most…
Abilify® (aripiprazole), a partial dopamine agonist, is an atypical antipsychotic drug, or second-generation antipsychotics (SGAs), with additional antidepressant qualities. It has been approved for the treatment of schizophrenia, bipolar disorder, and depression as an add-on treatment when the main antidepressant is not effective enough(1,3, 5). Aripiprazole is also used to treat symptoms of mood swings, aggression, irritability, and irritability associated with autistic disorder in pediatric…
are better tolerated than the older antipsychotic medications as they have different side effects (Preston et al, 2013). How Neurotransmitters Affected by Medications The Neurotransmitters move between different regions of the brain through nerve cells called receptors, which produces effects that can impact the memory, and voluntary movements of the muscles (Preston, O’Neal & Talaga, 2013). Antipsychotic medications work by blocking the dopamine receptor which helps to alleviate the symptoms…
PICOT: For psychiatric mental health staff nurses providing direct care to patients with mental health conditions and or dementia-related syndromes, would atypical second generation antipsychotics pharmacology program and screening tool for complications, during routine second generation antipsychotics medication management, increase nurse efficacy in SGA patient management? 1. Setting: The setting in which my project will take place is a Skilled Nursing Facility. SNFs are…
These drugs are most effective in treating the positive symptoms of schizophrenia, such as the hallucinations, delusions, aggressive impulses, and bizarre behaviors. Antipsychotic medications can be divided into two classes: first-generation (typical or conventional) and second-generation (atypical). It is thought that the typical antipsychotics work by blocking certain dopamine receptors (D2), while the atypical drugs are thought to block other dopamine receptors, such as D3 and D4, in…
Huntington disease is typically acquired as a genetic disorder. The characteristic genetic abnormality is trinucleotide repeat expansion of CAG in the HTT gene. In other words, genetically acquired DNA mutations result in abnormal function of the HTT gene, resulting in progressive neurodegeneration. Brain degeneration often affects a region called the caudate nucleus, which is part of the basal ganglia – this structure is critical for performing smooth motor movements. Injury to this region…
controversy of using atypical and typical antipsychotic drugs on patients with chronic schizophrenia, this meta-analysis will focus on the debate over which type of drug helps reduce symptoms more effectively. Using the most common antipsychotics, haloperidol for typical antipsychotic and olanzapine for an atypical antipsychotic, results will be tabulated across a range of scientific studies to conclude which drug has a better outcome of effectiveness for schizophrenic patients. Using the…
Both first generation antipsychotics (FGA’s) and second generation antipsychotics (SGA’s) are associated with a wide range of side effects that can lead to patient distress and noncompliance with treatment. First generation antipsychotics are strong D2 antagonists resulting in pronounced extra-pyramidal side effects and increased rates of hyperprolactinemia making them second-line treatments for schizophrenia (Werner). The SGA’s (risperidone, olanzapine, clozapine, quetiapine, paliperidone,…
entity to advise the patient on the best way of utilizing the prescribed medication (Branscum et al., 2012). There is also the need to assess the route of administering the medication (Broyles et al., 2013). This makes it possible to decide on the right and primary mode of giving the drugs (Branscum et al., 2012). Timing is of the essence in the administration of medication at all times (Branscum et al., 2012). Furthermore, the frequency of administration is an excellent pointer to the expected…
Aripiprazole is an atypical antipsychotic, second generation, indicated for schizophrenia and other psychoses, is an atypical antipsychotic drug approved by the FDA. The aripiprazole is an antipsychotic drug that works by changing the actions of chemicals in the brain. It is used to treat the symptoms of psychotic conditions such as schizophrenia and bipolar disorder, or with other medicines to treat major depressive disorder in adults. “Aripiprazole is also used to treat symptoms of…