An atypical antipsychotic that is used for the treatment of schizophrenia, schizoaffective disorder, and bipolar disorder that will be discussed is quetiapine (trade name Seroquel). Clinical trials studying the mechanism which quetiapine acts on iontropic glutamate receptors in comparison to haloperidol a convention antipsychotic and clozapine which is also an atypical antipsychotic show significant differences in their effects on NMDA, glutamatergic, and AMPA receptors elucidating possible explanations for the absence of EPS in atypical antipsychotic symptoms. In an analysis observing the possible gene expression modulation in NMDA and AMPA receptors suggests that each antipsychotic has a different effect than typical/conventional antipsychotics…
Aripiprazole is an atypical antipsychotic, second generation, indicated for schizophrenia and other psychoses, is an atypical antipsychotic drug approved by the FDA. The aripiprazole is an antipsychotic drug that works by changing the actions of chemicals in the brain. It is used to treat the symptoms of psychotic conditions such as schizophrenia and bipolar disorder, or with other medicines to treat major depressive disorder in adults. “Aripiprazole is also used to treat symptoms of…
such as atypical Second Generation Antipsychotics (SGAs). As with most medications, there are often times adverse drug reactions (ADRs) may be present and these effects can be quite troublesome, diminish the quality of life, thus patient outcome. The decision to put patients on certain medications is often a risk versus benefit or based on harm reductions. Justification for this topic of interest is to improve staff knowledge regarding some of our most…
2006). The drugs most often used to treat schizophrenia are referred to as antipsychotics or sometimes called neuroleptics. These drugs are most effective in treating the positive symptoms of schizophrenia, such as the hallucinations, delusions, aggressive impulses, and bizarre behaviors. Antipsychotic medications can be divided into two classes: first-generation (typical or conventional) and second-generation (atypical). It is thought that the typical antipsychotics work by blocking certain…
involvement with his recovery process, for understanding his illness and find ways to cope with Hector. Time: Early diagnosis can reduce the chances for relapse and decrease disruption in a person’s life. Interventions: (WebMD Home, 2016) Medications: Hector will need to stay current with his antipsychotic medications. Antipsychotic medications can control psychotic episodes, and chemicals in the brain called dopamine. (WebMD, 2014). These drugs do not cure, but helps relieve any symptoms of…
PICOT: For psychiatric mental health staff nurses providing direct care to patients with mental health conditions and or dementia-related syndromes, would atypical second generation antipsychotics pharmacology program and screening tool for complications, during routine second generation antipsychotics medication management, increase nurse efficacy in SGA patient management? 1. Setting: The setting in which my project will take place is a Skilled Nursing Facility. SNFs are…
Abilify® (aripiprazole), a partial dopamine agonist, is an atypical antipsychotic drug, or second-generation antipsychotics (SGAs), with additional antidepressant qualities. It has been approved for the treatment of schizophrenia, bipolar disorder, and depression as an add-on treatment when the main antidepressant is not effective enough(1,3, 5). Aripiprazole is also used to treat symptoms of mood swings, aggression, irritability, and irritability associated with autistic disorder in pediatric…
Rationale for NDDS (1500): NDDSs are being developed to overcome several limitations of conventional drug delivery systems. Although oral risperidone has superior efficacy to older antipsychotics and has remarkably less side effects (5), the greatest limitation with the use of risperidone for schizophrenia and bipolar disorder is non-compliance such as partial dosing or infrequent dosing by patients (6) Three quarter of all patients with schizophrenia are not compliant to their oral…
controversy of using atypical and typical antipsychotic drugs on patients with chronic schizophrenia, this meta-analysis will focus on the debate over which type of drug helps reduce symptoms more effectively. Using the most common antipsychotics, haloperidol for typical antipsychotic and olanzapine for an atypical antipsychotic, results will be tabulated across a range of scientific studies to conclude which drug has a better outcome of effectiveness for schizophrenic patients. Using the…
Huntington disease is typically acquired as a genetic disorder. The characteristic genetic abnormality is trinucleotide repeat expansion of CAG in the HTT gene. In other words, genetically acquired DNA mutations result in abnormal function of the HTT gene, resulting in progressive neurodegeneration. Brain degeneration often affects a region called the caudate nucleus, which is part of the basal ganglia – this structure is critical for performing smooth motor movements. Injury to this region…