An atypical antipsychotic that is used for the treatment of schizophrenia, schizoaffective disorder, and bipolar disorder that will be discussed is quetiapine (trade name Seroquel). Clinical trials studying the mechanism which quetiapine acts on iontropic glutamate receptors in comparison to haloperidol a convention antipsychotic and clozapine which is also an atypical antipsychotic show significant differences in their effects on NMDA, glutamatergic, and AMPA receptors elucidating possible explanations for the absence of EPS in atypical antipsychotic symptoms. In an analysis observing the possible gene expression modulation in NMDA and AMPA receptors suggests that each antipsychotic has a different effect than typical/conventional antipsychotics…
“The atypical antipsychotics with their proven efficacy against manic symptoms are emerging as candidates for use against the depressive phase of bipolar disorder” (Keck, 2005, p. 34). Antipsychotics are generally used for treatment of mania either alone or in a combination with mood stabilizers (Yatham, 2003). Risperidone, olanzapine and quetiapine have been examined in double blind, placebo-controlled trials for their efficacy in acute mania in monotherapy as well as in combination with mood…
I. Over view of anti-psychotics Antipsychotics are used primarily to help treat people who suffer from hallucinations or dilations. This includes individuals who suffer from Schizophrenia, Bi polar disorder, Dementia or unipolar depression. Antipsychotics can be broken down in to two different categories, Atypical and Typical however they tend to work similarly over all. The main standing difference between the two categories is that atypical antipsychotics block dopamine and have an effect on…
Medications Because some individuals exhibit more severe symptoms that others, there is not a standardized treatment for schizophrenia. None of the methods available today can cure this disorder and only help to ease the symptoms associated with it. Both antipsychotic and nonantipsychotic drugs and nonpharmacological interventions have all been used in the treatment of schizophrenic symptoms with antipsychotic being the most common method. Antipsychotic medications are a class of drugs used to…
Antipsychotic Medications and Treatment Antipsychotic medications have been developed over a period of years to helped clients suffering with psychosis such as schizophrenia (Perry, Alexander, Liskow & DeVane, 2007). There are two classes of medication which is described as first and second generation treatment (Perry et al,.2013). Psychosis is view as a disorder in which a client’s loses interaction with the reality of life and will need antipsychotics to treat those severe mental illnesses…
Antipsychotics are a rather complex method of treatment in treating schizophrenia. They come with many pros but also many cons You have to consider the emotional and physical effect the antipsychotics may have on an individual’s life. You also have to consider the drug and what it is supposed to treat. In this case it ultimately aids in the treatment of schizophrenia, but not everyone sees it as so. Some drugs can render more of the cons than the pros. Ultimately, with schizophrenia and…
Schizophrenia is a chronic disabling condition afflicting 1 percent of the population (1) and characterized by symptoms that can be broadly divided into three categories: positive, negative and cognitive. Positive symptoms of schizophrenia include perceptual disturbances in the form of auditory and visual hallucinations, delusions, disorganized speech and disorganized behavior. Negative symptoms may include lack of motivation, social withdrawal, poverty of speech and lack of pleasure. Seven…
Both first generation antipsychotics (FGA’s) and second generation antipsychotics (SGA’s) are associated with a wide range of side effects that can lead to patient distress and noncompliance with treatment. First generation antipsychotics are strong D2 antagonists resulting in pronounced extra-pyramidal side effects and increased rates of hyperprolactinemia making them second-line treatments for schizophrenia (Werner). The SGA’s (risperidone, olanzapine, clozapine, quetiapine, paliperidone,…
Children and Antipsychotics An Antipsychotic is a medication that tranquilizes individuals who have aggressive outbursts. This medication blocks neurotransmitters, causing the brain to not receive chemical messages. Antipsychotics being prescribed to children is a controversial issue because the drug(s) can affect the growth of the child physically and mentally but also has the ability to recline aggressive behavior. Children should not take antipsychotic drugs because the effects can cause…
Biomedical treatment refers to the branch of treatment that assists individuals diagnosed with psychological disorders with the help of prescription medication. According to Lisa Hartling (2012) in her article titled Antipsychotics in Adults with Schizophrenia: Comparative Effectiveness of First-Generation Versus Second-Generation Medications, there are 20 commercial first generation antipsychotics (FGA) and second generation antipsychotics (SGA) that have been approved by the Food and Drug…