“The atypical antipsychotics with their proven efficacy against manic symptoms are emerging as candidates for use against the depressive phase of bipolar disorder” (Keck, 2005, p. 34). Antipsychotics are generally used for treatment of mania either alone or in a combination with mood stabilizers (Yatham, 2003). Risperidone, olanzapine and quetiapine have been examined in double blind, placebo-controlled trials for their efficacy in acute mania in monotherapy as well as in combination with mood stabilizers including that of lithium and valproate (Yatham, 2003). Similarly, quetiapine has been found useful in improving symptoms of anxiety, sleep quality and overall quality of life when compared to placebo for patients with bipolar depression (Keck,
…show more content…
The characteristic symptoms of schizophrenia involve a range of cognitive, behavioral, and emotional dysfunction where no single symptom is pathognomonic of the disorder (DSM-5, 2013). Delusions, hallucinations, disorganized speech, grossly disorganized or catatonic behavior and negative symptoms are usually present in two or more for a significant amount of time during a 1 month period. Schizophrenia has an onset usually around late adolescence or early adulthood with progressive academic, social and occupational functional challenges following the onset of …show more content…
Individuals with schizophrenia health related quality of life may be influenced by factors such as disease symptoms, medication, physical well-being and social interaction (Bebbington, Angermeyer, Azorin, Marwaha, Marteau & Toumi, 2009). Without being treated, symptoms may limit individuals’ normal daily functioning and make social interaction and vocational rehabilitation very challenging. Atypical antipsychotics have been proven to have lower risks of extrapyramidal symptoms, but higher risk of metabolic adverse events (Guo, Fang, Zhai, Wang, Wang, Hu, Sun, Lv et al., 2011). Research conducted through schizophrenia outpatient health outcomes study found that patients on clozapine and olanzapine have a lower risk of relapse while patients on olanzapine have a higher risk of remission than typical antipsychotics (Guo, Fang, Zhai, Wang, Wang, Hu, Sun, Lv et al.,
The characteristic symptoms of schizophrenia involve a range of cognitive, behavioral, and emotional dysfunction where no single symptom is pathognomonic of the disorder (DSM-5, 2013). Delusions, hallucinations, disorganized speech, grossly disorganized or catatonic behavior and negative symptoms are usually present in two or more for a significant amount of time during a 1 month period. Schizophrenia has an onset usually around late adolescence or early adulthood with progressive academic, social and occupational functional challenges following the onset of …show more content…
Individuals with schizophrenia health related quality of life may be influenced by factors such as disease symptoms, medication, physical well-being and social interaction (Bebbington, Angermeyer, Azorin, Marwaha, Marteau & Toumi, 2009). Without being treated, symptoms may limit individuals’ normal daily functioning and make social interaction and vocational rehabilitation very challenging. Atypical antipsychotics have been proven to have lower risks of extrapyramidal symptoms, but higher risk of metabolic adverse events (Guo, Fang, Zhai, Wang, Wang, Hu, Sun, Lv et al., 2011). Research conducted through schizophrenia outpatient health outcomes study found that patients on clozapine and olanzapine have a lower risk of relapse while patients on olanzapine have a higher risk of remission than typical antipsychotics (Guo, Fang, Zhai, Wang, Wang, Hu, Sun, Lv et al.,