The cyano-ethoxy carbonyl protection Manoharan et al. (1999) developed 2(cyanoethoxycarbonyloxy)succinimide S.27a a stable, crystalline, and convenient reagent for the protection of pendant akylamines in oligonucleotides (Figure X.X.X). The 2-cyanoethyl (ce) group is the most common phosphate protecting group in oligonucleotides; however, ce and corresponding 2-(cyanoethoxycarbonyl) group were not utilized for the nucleobase protection until 2000. Merk et al. (2000) developed 2-(cyanoethoxy)carbonyl (ceoc) protection for the protection of the excocylic amino group of adenine, guaninine, and cytosine. The (2-cyanoethoxy)carbonylation reactions were carried out with either 2-cyanoethyl carbonochloridate (S.27b ) or 1-((2-cyanoethoxy)carbonyl)-3-methyl-1H -imidazolium chloride (S.27c) (Figure X.X.X), which were synthesized by the…
Flow batteries have been around since the 1970’s this technological advance in the field of energy storage and acts as a fuel cell which can provide a new and efficient energy supply. One of the biggest advantages of flow batteries is that they can practically in an instance recharge just by replacing the electrolyte liquid,while this happens it is recovering the spent materials for recharge. Several different flow batteries have been developed, including Redox, Hybrid and, Membraneless. The…
Demonstration of Cellular Respiration Inside Lima Beans Cells in Vitro Purpose: Cellular respiration is a series of metabolic reactions that take place in the mitochondria and produce chemical energy in the form of ATP by the breakdown of food molecules.There are three processes involved in cellular respiration; glycolysis, the Krebs cycle and the electron transport chain. During this processes, glucose is oxidized by a series of redox reactions and its electrons and hydrogen ions are donated…
phosphate and deoxyribose backbone, and four different nitrogenous bases. These bases are adenine, guanine, cytosine, and thymine. Ribonucleic acid, the molecule formed in the transcription of DNA, is made up of phosphate, ribose, and adenine, guanine, cytosine, and uracil. The backbone of DNA consists of a phosphate bonded to a deoxyribose molecule. Deoxyribose is a sugar containing five carbons, and it is called deoxyribose as it is missing an oxygen atom on C2. The sugar found in RNA is…
The structure of DNA is a double helix, like a twisted ladder. The rungs each consist of two bases, either a pair of adenine and thymine, or a pair of cytosine and guanine, and the bases are shuffled, on different sides of the rings in a sequence. The sides of the of the 'ladder' are alternating sugars and phosphate groups. (Sugar-phosphate backbone) On one side of the ladder, the sugars are facing upwards, and on the other they are facing down. Each nucleotide has one deoxyribose sugar(without…
tRNA models: cytosine, uracil, and adenine (CUA); cytosine, guanine, and guanine (CGG); adenine, uracil, and guanine (AUG). Anticodons were attached to their complementary codons using hydrogen bond connectors and each amino acid was bonded to its respective tRNA. The amino acid models were bonded together using the white bonding tubes. The amino acid sequence was detached and compared. All parts were detached and returned to bag. Results In this lab, a DNA model was constructed and then the…
1. a) The three parts of a nucleotide are phosphate, nitrogen-containing base, and the deoxyribose sugar. b) Deoxyribose sugar is the sugar that is found in a nucleotide. c) The nitrogen-containing base is the nucleotide component that contains nitrogen. d) The four nitrogen bases shown in Model 1 are Adenine, Thymine, Guanine, and Cytosine. 2. a) I pointed at a single nucleotide on the ladder model of DNA, on the worksheet. The nucleotide included phosphate, nitrogen-containing base, and…
This paper is going to describe the replication of DNA and RNA and the processes of transcription and translation of protein synthesis. What is DNA? DNA is a nucleic acid that carries the genetic information in cells and some viruses, consisting of two long chains of nucleotides twisted into a double helix and joined by hydrogen bonds between the complementary bases adenine and thymine or cytosine and guanine. DNA sequences are replicated by the cell prior to cell division and may include genes,…
DNA is an important molecule for life. It is much like a manual telling the instructions of how bodies develop and function. DNA is the acronym for deoxyribonucleic acid. What is DNA made of? DNA is a molecule of nucleotides, such as adenine, thymine, cytosine, and guanine. They are shown by their first letter: A- Adenine T- Thymine C- Cytosine G- Guanine The backbone that holds the nucleotides are called phosphate and deoxyribose. The nucleotides are known as bases. Human body has about 210…
Adenine and Guanine are Purines as they have a double ring structure whereas Cytosine and Thymine are Pyrimidines as they have a single ring structure. These bases, attached to the sugar-phosphate back bone of both strands, join adjacently in a complimentary fashion. This means that a purine will bind to a pyrimidine therefore Adenine always binds with Thymine, which forms two hydrogen bonds, and Guanine always binds with Cytosine, which forms three hydrogen bonds. This is known as complimentary…