Spleen

experiments I realize my unknown organism was Salmonella Typhimurium. Salmonella Typhimurium was originally isolated in 1880 by Karl J. Erberth. S. typhimurium is a multi-organ pathogen that inhabits the lymphatic tissues of the small intestine, liver, spleen, and bloodstream of infected humans. It is not known to infect animals and is most common in developing countries with poor sanitary systems and lack of antibiotics, putting travelers to Asia, Latin America, and Africa in a high-risk…

Symptoms from this deficiency include “enlarged liver and spleen (hepatosplenomegaly), poor weight gain, low muscle tone, a yellow tint to the skin and the whites of the eyes (jaundice), vomiting, diarrhea, developmental delay, low amounts of iron in the blood (anemia), and poor absorption of nutrients from food…

Typhoid Fever You have no doubt heard about the notorious case of Typhoid Mary. Mary Mallon, more commonly known by the title of Typhoid Mary, was a cook who resided in New York City who was responsible for unwittingly infecting nearly 53 people with typhoid and causing 3 deaths as a result. Despite being prohibited from continuing to work as a cook, she took up a new identity to continue working. This led to another typhoid outbreak that led to her being forced into quarantine for nearly 30…

The lymphatic system is a serious of ducts, nodes, nodules and lymph vessels among other structures and components that teams up to fight off bacteria and foreign substances that enter the body. The system is part of the immune system and it relies on various types white blood cells called lymphocytes that fight off bacteria, reduce inflammation, and respond to allergic reactions. The white blood cells are produced in the marrow of the bones beginning as stem cells. The stem cells…

sequestration is another common complication; rising when the sickle cells become clogged and are trapped in the spleen causing rapid splenomegaly and pain (National Heart, Lung and Blood Institute, 2015). For many patients with SCD the spleen ceases to function due to repeated episodes of sequestration. Since the spleen plays a vital role in filtering blood and preventing infection, spleen dysfunction further increases morbidity and mortality for patients with SCD (Johns Hopkins Medicine,…

changes in the way the bone marrow makes blood cells. This gene is called JAK2. The gene is not passed down through families. PV is a long-term disease that tends to get worse over time. You may have overproduction of blood cells in your liver and spleen. These organs may become…

a condition in which red blood cells are shaped like spheres instead of flat discs. Because of their unusual shape, the HS red blood cells have difficulty passing through the spleen, the organ that rids the blood of dead cells and bacteria. Those affected by this condition experience anemia, jaundice, and an enlarged spleen (NLM “Hereditary Spherocytosis”). In Cystic fibrosis, a defective gene causes a buildup of thick, sticky mucus that obstructs the passages of many of the body’s organs. The…

Haemophilus influenzae is a gram-negative, nonmotile, rod-shaped bacterium that is considered pleomorphic. There are six different identifiable strains of Haemophilus influenzae (type a-f). Haemophilus influenzae type b (Hib) is the most common strain and is responsible for the most cases of serious infection (Centers for Disease Control and Prevention, 2010). Haemophilus influenzae type b is transmitted from person-to-person through respiratory droplets and direct contact with respiratory…

Hemochromatosis What is Hemochromatosis? Hereditary Hemochromatosis is an iron disorder in which the body simply loads too much iron. Too much iron can lead to life threating conditions, such as liver diseases, heart problems and diabetes. Hemochromatosis is most often seen in people who have two copies of this C282Y mutation (one from the mother and one from the father). Hemochromatosis is not something that be cured, the patient will need to be monitored and treated for the rest of his life…

• Fatigue. • Swollen glands (lymph nodes). • Painful mouth ulcers. • Gum disease. DIAGNOSIS This condition may be diagnosed based on: • Your medical history. • A physical exam to check for swollen lymph nodes and an enlarged spleen. Your spleen is an organ on the left side of your body that stores white blood…