Hemochromatosis Research Paper

Improved Essays
What is Hemochromatosis? Hereditary Hemochromatosis is an iron disorder in which the body simply loads too much iron. Too much iron can lead to life threating conditions, such as liver diseases, heart problems and diabetes. Hemochromatosis is most often seen in people who have two copies of this C282Y mutation (one from the mother and one from the father). Hemochromatosis is not something that be cured, the patient will need to be monitored and treated for the rest of his life. However, iron overload is curable. Iron is an essential nutrient found in many foods. Iron carries oxygen to all parts of the body. Normally, humans take in 8-10% of the iron in foods that they eat. People with Hemochromatosis can take in four
…show more content…
A person with severe iron overload may need to give blood as much as 8 times in a single month! The goal is to bring blood ferritin levels to an ideal range of 50-150ng/mL. Depending on the amount of iron overload at the time of diagnosis, reaching normal levels can require several phlebotomies. Serum ferritin drops about 30ng/mL with each full unit (500cc) of blood removed. When ferritin falls more rapidly following a phlebotomy, there is likely some other reason for the fast rate other than the blood donation. These reasons are specific to the individual but can include the presence of inflammation, changes in alcohol consumption, or changes to medication. Once iron levels reach normal, a person can begin maintenance therapy, which involves making a blood donation every 2 to 4 months for life. Some people may need to give blood depending on what they eat and how quickly their body absorbs iron. The TS% and serum ferritin tests can be done periodically to help determine how often blood should be removed. When hemochromatosis is diagnosed early and treated before organs are damaged, a person can live a normal life expectancy. For people who have the disease at the time of diagnosis, life expectancy may be shortened depending on the disease. If a person is diagnosed and treated before serum ferritin is above 1,000ng/mL the risk of liver cancer is less than

Related Documents

  • Improved Essays

    overload? You may be asking yourself, what exactly causes hemochromatosis? The main reason that causes hereditary hemochromatosis is when a person inherits two mutated copies of the HFE gene from each parent. Both genders have the same chance of inheriting the gene Not everyone with the HFE gene develops the disease Summary and Conclusion If your body cannot maintain a healthy and regular amount of iron, you are in risk of Hemochromatosis aka Iron Storage Disease. The condition can be caught…

    • 412 Words
    • 2 Pages
    Improved Essays
  • Improved Essays

    than most people. For many years, hemochromatosis has been a mystery to medicine, and scientists all over the world have investigated the causes and symptoms of this hereditary disorder, and identified its precise location in the chromosomes. Hemochromatosis has been nicknamed “Bronze diabetes”, because it may be accompanied by diabetes mellitus and increased skin pigmentation (darkening…

    • 816 Words
    • 4 Pages
    Improved Essays
  • Decent Essays

    between each "department" of the body. But this does not always occur due to diseases that affect thousands of people day after day. In 2008, my uncle was stricken with a disease called hemochromatosis. It is a disease that can be hereditary or secondary, but is highly related genetic conditions. Hereditary hemochromatosis is a classic example of a genetic disorder that changes the way in which iron absorption is made, resulting in the accumulation of iron in body tissues and toxicity. The most common…

    • 185 Words
    • 1 Pages
    Decent Essays