Southern Literary Messenger

The “Grandfather of Goth”(Semtner) Edgar Allan Poe was born in Boston on January 19, 1809. He was born into a family of performers, causing a lot of traveling. However, at the age of three both of his parents had died of tuberculosis. A tobacco merchant names John Allan adopted him, now his new family accepted Poe as their own and gave him everything. Soon, his new family moved to London and Poe studied in England. After returning home Poe grew a love for writing, he was inspired by a poet before him named Lord Byron. However, John Allan did not want Poe to follow that dream, because he knew there would be no financial award, he disowned Poe, another reason for the break was that Poe was an alcoholic and had gambling issues. Edgar Allan Poe then followed his dreams and began to write poems and short stories. Throughout the Romantic period of literature, Edgar Allan Poe was a Dark Romantic American writer who had many different thoughts, with the madness in his brain and the influence of others, to show the difference between American Romanticism and Dark Romanticism throughout the 1800s. Edgar Allan Poe was a Dark Romantic American writer who used many themes to differentiate himself from other writers in his time. One of these themes is darkness, this is one of the main themes to be classified as a dark romantic poet. Dark themes could mean many things, and can also symbolize others. Some of these dark themes are death and mourning. These themes are evident in Poes poems…

Raymond Carver is one of the men accredited for reviving the contemporary short story genre. He was an excessive drinker and this shaped his stories along with the qualities of minimalism and dirty realism. Edward Hopper was an American painter that specialized in realism. Hopper’s artwork depicted the accurate, detailed, and embellished nature of contemporary life. Raymond Carver’s short story “Cathedral” and Edward Hopper’s painting Room in New York both exhibit someone examining a…

Symbolism is defined as “the use of symbols to signify ideas and qualities by giving them symbolic meanings that are different from their literal sense” (Symbolism - Examples and Definition of Symbolism). If people pay close attention they can find that a detail that seems insignificant can have a valuable representation. Lois Lowry implements elements of symbolism throughout The Giver series, some elements more obvious than others. The red sled, the color blue and the Forest all consist of a…

In modern molecular biology and genetics, the genome is the genetic material of an organism. It consists of DNA (or RNA in RNA viruses). The genome includes both the genes and the non-coding sequences of the DNA/RNA. Understanding Human Genetic Variation Genetics is the scientific study of inherited variation. Human genetics, then, is the scientific study of inherited human variation. We study genetic material due to following reasons; 1. One reason is simply an interest in better understanding…

Prokaryote DNA replication is a semi conservative, bidirectional, template driven process. The phrase ‘semi-conservative’ refers to the fact that the newly synthesised double stranded DNA is made up of one parental (existing) strand, and one newly synthesised strand. The parental duplex is not ‘conserved’ as an entity. This was proved by the Meselson-Stahl experiment by replicating E.Coli in different mediums of of different Nitrogen isotopes. The results consisted of half of normal weight and…

Each gene has instructions to make or build a protein. In protein coding the sequence is always in groups of three nucleotides. These groups of three are called codons. Every codon has one amino acid in a protein. All proteins need to start with the ATG codon. Most biological activities are carried out by proteins. In order to have the DNA sequence that reads ATG-ACT-CAT-GAG-TGA to be translated into the RNA to build a protein there has to be proteins that are not the same to be able to…

Proposed research: Aims and Objectives: Aim1: To address the roles of the Hira complex in rRNA transcription and embryonic development Aim2: To characterise rDNA chromatin organisation in the oocyte Aim3: To elucidate the transcriptional machinery of RNA Polymerase I in the oocyte Experimental Approach: Aim1: To address the roles of the Hira complex in rRNA transcription and embryonic development The Hira histone chaperone complex is an evolutionarily conserved complex, which is composed of…

Differential alternative splicing human tissue network analysis of GUK1 Result Figure 4.12: Visualisation of alternative splicing gene GUK1 in human tissues. Differential alternative splicing genes between two different tissues comparison were shown on a different visualisation platform and tools in comparison with network analysis. (A) rMATS analysis. Histogram shows inclusion level ψ, per sample for each tissue comparisons. In this case, only exon 3 found as statistically alternative…

Transfer RNA Transfer RNA (tRNA) is a crucial component in Protein Synthesis. It serves as an adaptor molecule between the codon, the three nucleic acids and the amino acid after which a specific protein will be synthesized. It is the intermediate in Protein Synthesis which interprets the genetic code. Without tRNA, translation in prokaryotes or eukaryotes could not take place. Common Features of tRNA Molecule Each amino acid has at least one tRNA molecule. Therefore, these tRNA molecules have…

The Basics of Gene Expression and Control Genetics is a very diverse field of science, because it encompasses so many aspects of not only what happens inside organisms, but also how offspring relate to parents and ancestors and many other processes. Although every bit of genetics is important, many things in an organism would not be possible without the expression of genes. Through expressions of genes, organisms provide for themselves and "fulfill" what is the basis of their genetic…