Partition coefficient

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  • Analysis Of Prazosin Hydrochloride

    RESULT AND DISCUSSION 7.1. Preformulation studies 7.1.1. Identification of pure drug by FTIR Figure7.1: Identification of Sample through FTIR Figure 7.2: FTIR Spectrum of Standard Prazosin hydrochloride (with references of B.P.- 2009) Table: 7.1 - Characteristics peaks of Prazosin hydrochloride S.No. Reference peaks (cm-1) Theoretical peak of Prazosin hydrochloride Obtained peaks (cm-1) Functional Group Stretching/ Bending 1 1750-1680 1529.92 1529.92 C=O Stretching 2. 1650-1580…

    Words: 1483 - Pages: 6
  • Nt1310 Unit 4 Lab 4

    Molecular Electrostatic Potential, LogP, and LUMO Energy are also being explored during this lab. Molecular Electrostatic Potential allows for scientists and chemists to calculate the atomic charges of large molecules. LogP is also known as the partition coefficient which is the ratio of concentrations of a compound in a mixture during two phases at equilibrium. LogP can be used to find distributions of chemical compounds in drugs, and how well those drugs can reach and affect their intended…

    Words: 367 - Pages: 2
  • Big White Pig Regressions

    Genetic parameters were estimated using B-spline functions in random regression models for weight of Large White pigs measured between the 3rd and 36th week of age. The model accounted for contemporary groups, parity and sex as fixed effects while random effects modelled were; animal genetic effect, permanent environmental effect and maternal genetic effect along with heterogeneous residual variances. Heritability estimates decreased with age from 0.37 at 3 weeks to 0.27 at 36 weeks. Weight…

    Words: 1181 - Pages: 5
  • Advantages And Disadvantages Of Sublingual Mucosa

    many other factors: lipophilicity, solubility in saliva, pH, binding to the oral mucosa, and oil-to-water partition coefficient of drugs. Drugs that have higher lipophilicity and a good solubility in saliva have good absorption in sublingual route. Drugs remain unionized at pH of 6.0 and have poor binding to oral mucosa increase absorption too. Also, drugs with oil-water partition coefficient range…

    Words: 1163 - Pages: 5
  • Tragic Shipwrecks

    On April 15th in 1912, one of the most tragic shipwreck happened. The Titanic ship sunk under the Atlantic Ocean after colliding with an iceberg. A lot of people died during the accident. Small number of available lifeboats was one of the main reasons that led to such a high number of deaths. Such factors as sex, class, age, and others also significantly contributed to the likelihood of survival. Introducing different statistical methods, I will classify what sorts of people had a better chance…

    Words: 1676 - Pages: 7
  • Investigating The Experiment On AISI 316 Austenite Stainless Steel

    T.T.M Kannan et al. [2014] performed the experiment on AISI 316 Austenite stainless steel to investigate the heat partition, tool wear and tool life. In their investigation they found that CBN cutting inserts has been damaged in moderate cutting velocity and produce good machinability and higher cutting temperature decreases the yield strength of produced white layer. [11] R.Suresh et al. [2014] studied the effect of various cutting parameters in hard turning of AISI H13 steel at 55 HRC with…

    Words: 701 - Pages: 3
  • Importance Of Biopharmaceutics

    Biopharmaceutics This is the in-vivo or in-vitro study of various physiochemical factors including developmental and design factors affecting the rate and extent of drug absorption with regards to the pharmacological effect of the drug. Biopharmaceutical studies use this result to improve likely problems that could arise from poor drug absorption and increase the bioavailability of newly formulated drugs. The main purpose of biopharmaceutical studies is to increase, monitor and maintain the rate…

    Words: 1493 - Pages: 6
  • Polymerase Chain Report

    The random amplified polymorphic DNA-polymerase chain reaction (RAPD-PCR) method was used to examine the genetic variability of Aiolopus thalassinus (Fabr.) populations at heavy metal polluted and unpolluted locations of different geographical distances. Four primers yielded a total of 69 scorable bands, which are all polymorphic. Cluster and Principal component analysis separated the inside and outside Cairo populations into two main branches that were further separated into smaller ones,…

    Words: 1664 - Pages: 7
  • Mapreduce Rendezvous Hasing Based Virtual Hierarchies: The Cassandra Nosql Case Study

    MR-RHVH framework apply the distributed structure of nodes using MapReduce, that equally partition data amongst Cassandra nodes using mapper and reducer functions. The MR-RHVH framework consists of three main layers, as shown in figure 2, Cassandra/Hadoop Cluster, MRRHVH, Cassandra/Hadoop Data Center and Hadoop/MapReduce applier. Cassandra clients…

    Words: 2262 - Pages: 10
  • Biopharmaceutical Classification System Case Study

    Determination of permeability Methods range from simple oil/water partition coefficient to absolute bioavailability studies. These include human studies, in vivo intestinal perfusion in a suitable animal model, in vitro permeability methods using excised intestinal tissues and monolayers of suitable epithelial cells. Solubility…

    Words: 992 - Pages: 4
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