Gene expression

Introduction Evolution Canyon is a canyon in Israel where the two slopes face very different conditions. The Northern Facing Slope (NFS) is lush, green, and shaded while the Southern Facing Slope (SFS) is dry and has little protection from intense sunlight. Evolution Canyon is a natural laboratory, meaning that nature has provided variations, allowing it to be a great location for experiments. Specifically, it is a great location to study natural selection and evolution. Researches from the…

channel to exist endoplasmic reticulum. Deletion of amino acids including phenylalanine reduces surface expression of KATP channels on the plasma membrane (Ashcroft, 2005). Another mutation that cause abnormal trafficking and is also common in the Ashkenazi population is the deletion codon for F1388. The inactivation of RKR ER retention signal in F1388-SUR1 leads to minimal surface expression (Nestorowicz et al., 1996). This means Kir6.2 is expressed more on the surface and the inhibitory effect…

instructions to proteins. The central dogma explain the flow of genetic material; starting with replication of DNA then transcription of DNA to RNA and finally translation from RNA to protein. DNA replication is needed to conserve the continuous gene expression. In most prokaryotes and eukaryotes DNA is double stranded, and during replication the strands split in half…

DNA with an identical sequence of nucleotide bases. They have this epigenome inside and it is a set of chemical switches looking like a beacon that has the ability to control the gene expression within a cell. It's like a second layer of information that tells genes how to act. By turning some genes on and leaving some genes off, turning some cell into brain cells, bone, or skin and sometimes it may also trigger unexpected differences. That may set identically tends from different parts before…

In the science field, a lot of the time research can be portrayed differently in popular press articles, for example newspaper or magazine articles, compared to the scientific article published from a peer-reviewed journal. Sometimes newspaper or magazine articles can forget or exaggerate certain results. This is why it is always important to read not only the popular press literature but also to read the material from which the popular press got its information. The journal article I chose to…

embryos started off in China, moved to the United Kingdom and is still being observed by the FDA in the United States; this is making progress and is actually happening. Like, anything there are issues that can occur from scientists who altered the genes of embryos, which that’s discussed in the paper, as well as why it feels as if something as genetically altering embryos is something that many felt was a line that should have never crossed.…

eventually concluding in severe visual impairment, may be inherited as X-linked, autosomal dominant and autosomal recessive. Many genes had been involved with this disease. In this research work we focus on autosomal dominant retinitis pigmentosa and the splicing factor PRPF31. Degeneration of photorreceptors appear to be related with mutations in pre-mRNA splicing gene and splicing process. In this research…

Down Syndrome is the most prevalent and recognizable chromosomal abnormality in live born children, with a current prevalence of 2.8 out of 1000 children born with the genetic disorder [1]. In 1866, John Langdon Down termed the condition “mongolism” before it was later termed Down syndrome in honor of his discovery. Nearly a century later, geneticists Jerome Lejeune and Patricia Jacobs reported the chromosomal abnormality for the first time in humans to be secondary to a trisomy of chromosome 21…

As described in Sharon Moalem’s essay on epigenetics, “Changing Our Genes: How Trauma, Bullying and Royal Jelly Alter Our Genetic Destiny," researchers have uncovered the relationship between environmental changes and the impact these changes can have on future generations. Carrying that theory out just a little further, why can’t the role of technology today affect future generations? According to Moalem, individual genes can be turned off and on by our life experiences – called epigenetics.…

autosomal dominant genetic disorder that primarily affects the skin, lungs, and kidneys. Autosomal dominant disorder means an abnormal gene that cause the disease is passed down from one parent, and men and women are likely to be equally affected, which means each offspring has a 50% chance of having the disease. It is caused by mutations in the folliculin (FLCN) gene.…